Cardiovascular responses to retigabine in conscious rats - under normotensive and hypertensive conditions

Pharmacological dissection of Kv7.1 channels in systemic and pulmonary arteries

(2012) Preet S Chadha et al.   BRITISH JOURNAL OF PHARMACOLOGY

One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders

(2012) TA Jepps et al.   BRITISH JOURNAL OF PHARMACOLOGY

The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy

(2012) Martin J. Gunthorpe et al.   EPILEPSIA

The urinary safety profile and secondary renal effects of retigabine (ezogabine): A first-in-class antiepileptic drug that targets KCNQ (Kv7) potassium channels

(2012) Neil Brickel et al.   EPILEPSIA

Reduced KCNQ4-Encoded Voltage-Dependent Potassium Channel Activity Underlies Impaired β-Adrenoceptor–Mediated Relaxation of Renal Arteries in Hypertension

(2012) Preet S. Chadha et al.   HYPERTENSION

Role of KCNQ Channels in Skeletal Muscle Arteries and Periadventitial Vascular Dysfunction

(2012) Olga Zavaritskaya et al.   HYPERTENSION

The efficacy and safety of retigabine and other adjunctive treatments for refractory partial epilepsy: A systematic review and indirect comparison

(2012) Marrissa Martyn-St James et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Guide to Receptors and Channels (GRAC), 5th edition

(2011) SPH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Downregulation of Kv7.4 Channel Activity in Primary and Secondary Hypertension

(2011) Thomas A. Jepps et al.   CIRCULATION

Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantitative comparison of cellular and cardiovascular pharmacological responses

(2011) Jillian G. Baker et al.   FASEB JOURNAL

A Novel Degradation Signal Derived from Distal C-terminal Frameshift Mutations of KCNQ2 Protein Which Cause Neonatal Epilepsy

(2011) Jun Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional role of M-type (KCNQ) K+channels in adrenergic control of cardiomyocyte contraction rate by sympathetic neurons

(2011) Oleg Zaika et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ezogabine (retigabine)

(2011) Carl E. Stafstrom et al.   NATURE REVIEWS DRUG DISCOVERY

Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy

(2011) J. A. French et al.   NEUROLOGY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Expression and function of the K+ channel KCNQ genes in human arteries

(2010) Fu Liang Ng et al.   BRITISH JOURNAL OF PHARMACOLOGY

Possible involvement of GLP-1(9-36) in the regional haemodynamic effects of GLP-1(7-36) in conscious rats

(2010) SM Gardiner et al.   BRITISH JOURNAL OF PHARMACOLOGY

Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy

(2010) M. J. Brodie et al.   NEUROLOGY

A Full Pharmacological Analysis of the Three Turkey β-Adrenoceptors and Comparison with the Human β-Adrenoceptors

(2010) Jillian G. Baker   PLoS One

Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats

(2009) W-S Vanessa Ho et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neural KCNQ (Kv7) channels

(2009) David A Brown et al.   BRITISH JOURNAL OF PHARMACOLOGY

Treatment with the Kv7 potassium channel activator flupirtine is beneficial in two independent mouse models of pulmonary hypertension

(2009) I Morecroft et al.   BRITISH JOURNAL OF PHARMACOLOGY

Expression, Localization, and Pharmacological Role of Kv7 Potassium Channels in Skeletal Muscle Proliferation, Differentiation, and Survival after Myotoxic Insults

(2009) F. A. Iannotti et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

KCNQ Modulators Reveal a Key Role for KCNQ Potassium Channels in Regulating the Tone of Rat Pulmonary Artery Smooth Muscle

(2009) S. Joshi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Vascular KCNQ Potassium Channels as Novel Targets for the Control of Mesenteric Artery Constriction by Vasopressin, Based on Studies in Single Cells, Pressurized Arteries, and in Vivo Measurements of Mesenteric Vascular Resistance

(2008) A. R. Mackie et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Molecular pharmacology and therapeutic potential of neuronal Kv7-modulating drugs

(2007) F MICELI et al.   CURRENT OPINION IN PHARMACOLOGY

The KCNQ/M-current modulates arterial baroreceptor function at the sensory terminal in rats

(2007) Cynthia L. Wladyka et al.   JOURNAL OF PHYSIOLOGY-LONDON