The antidote effect of quinone oxidoreductase 2 inhibitor against paraquat-induced toxicityin vitroandin vivo

Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease

(2011) Susan Duty et al.   BRITISH JOURNAL OF PHARMACOLOGY

Resveratrol interacts with estrogen receptor-β to inhibit cell replicative growth and enhance stress resistance by upregulating mitochondrial superoxide dismutase

(2011) Ellen L. Robb et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H2O2

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The protective effect of tianeptine on Gp120-induced apoptosis in astroglial cells: role of GS and NOS, and NF-κB suppression

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Inactivation of the Quinone Oxidoreductases NQO1 and NQO2 Strongly Elevates the Incidence and Multiplicity of Chemically Induced Skin Tumors

(2010) J. Shen et al.   CANCER RESEARCH

Melatonin signaling and cell protection function

(2010) Francesca Luchetti et al.   FASEB JOURNAL

Protective effect of quercetin against paraquat-induced lung injury in rats

(2010) Hee K. Park et al.   LIFE SCIENCES

The Role of NADPH Oxidase 1–Derived Reactive Oxygen Species in Paraquat-Mediated Dopaminergic Cell Death

(2009) Ana Clara Cristóvão et al.   ANTIOXIDANTS & REDOX SIGNALING

Functional polymorphisms, altered gene expression and genetic association link NRH:quinone oxidoreductase 2 to breast cancer with wild-type p53

(2009) K.-D. Yu et al.   HUMAN MOLECULAR GENETICS

Paraquat Toxicity Induced by Voltage-dependent Anion Channel 1 Acts as an NADH-dependent Oxidoreductase

(2009) Hiroki Shimada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Postmortem Analyses Unveil the Poor Efficacy of Decontamination, Anti-Inflammatory and Immunosuppressive Therapies in Paraquat Human Intoxications

(2009) Ricardo Jorge Dinis-Oliveira et al.   PLoS One

Differential Contribution of the Mitochondrial Respiratory Chain Complexes to Reactive Oxygen Species Production by Redox Cycling Agents Implicated in Parkinsonism

(2009) Derek A. Drechsel et al.   TOXICOLOGICAL SCIENCES

Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease

(2008) Derek A. Drechsel et al.   FREE RADICAL BIOLOGY AND MEDICINE

Iron-enhanced paraquat-mediated dopaminergic cell death due to increased oxidative stress as a consequence of microglial activation

(2008) Jun Peng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Quinone Reductase 2 Is a Catechol Quinone Reductase

(2008) Yue Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An effective antidote for paraquat poisonings: The treatment with lysine acetylsalicylate

(2008) R.J. Dinis-Oliveira et al.   TOXICOLOGY

Parkinson's disease and pesticides: a toxicological perspective

(2008) J HATCHER et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Paraquat Poisonings: Mechanisms of Lung Toxicity, Clinical Features, and Treatment

(2007) R. J. Dinis-Oliveira et al.   CRITICAL REVIEWS IN TOXICOLOGY