Positive allosteric modulation by ivermectin of human but not murine P2X7 receptors

Functional expression of P2X4 receptor in capillary endothelial cells of the cochlear spiral ligament and its role in regulating the capillary diameter

(2011) T. Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Guide to Receptors and Channels (GRAC), 5th edition

(2011) SPH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions

(2011) Lisa Y. Lenertz et al.   IMMUNOLOGIC RESEARCH

Clemastine Potentiates the Human P2X7 Receptor by Sensitizing It to Lower ATP Concentrations

(2011) Wolfgang Nörenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Determinants of Ivermectin Sensitivity at the Glycine Receptor Chloride Channel

(2011) Timothy Lynagh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium-dependent block of P2X7 receptor channel function is allosteric

(2011) Zonghe Yan et al.   JOURNAL OF GENERAL PHYSIOLOGY

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

Activation and Regulation of Purinergic P2X Receptor Channels

(2011) C. Coddou et al.   PHARMACOLOGICAL REVIEWS

Electrophysiological classification of P2X7 receptors in rat cultured neocortical astroglia

(2010) W Nörenberg et al.   BRITISH JOURNAL OF PHARMACOLOGY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Rodent Cortical Astroglia Express In Situ Functional P2X7 Receptors Sensing Pathologically High ATP Concentrations

(2010) João Filipe Oliveira et al.   CEREBRAL CORTEX

Experimental Characterization and Mathematical Modeling of P2X7 Receptor Channel Gating

(2010) Z. Yan et al.   JOURNAL OF NEUROSCIENCE

Nicotinic Acetylcholine Receptor Transmembrane Mutations Convert Ivermectin from a Positive to a Negative Allosteric Modulator

(2010) T. Collins et al.   MOLECULAR PHARMACOLOGY

Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death

(2010) G Burnstock et al.   Cell Death & Disease

A P2X receptor from the tardigrade species Hypsibius dujardini with fast kinetics and sensitivity to zinc and copper

(2009) Selvan Bavan et al.   BMC EVOLUTIONARY BIOLOGY

Mechanism of action of species-selective P2X7 receptor antagonists

(2009) Anton D Michel et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antagonists of the P2X7Receptor. From Lead Identification to Drug Development

(2009) Simon D. Guile et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

Increase of intracellular Ca2+ by P2X and P2Y receptor-subtypes in cultured cortical astroglia of the rat

(2009) W. Fischer et al.   NEUROSCIENCE

P2X1 and P2X5 Subunits Form the Functional P2X Receptor in Mouse Cortical Astrocytes

(2008) U. Lalo et al.   JOURNAL OF NEUROSCIENCE

ATP-gated P2X cation-channels

(2008) Michael F. Jarvis et al.   NEUROPHARMACOLOGY

Identification of P2X4 receptor transmembrane residues contributing to channel gating and interaction with ivermectin

(2008) Irena Jelínkova et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Modulation of P2X7 receptor functions by polymyxin B: crucial role of the hydrophobic tail of the antibiotic molecule

(2007) D Ferrari et al.   BRITISH JOURNAL OF PHARMACOLOGY