Mitochondria in traumatic brain injury and mitochondrial-targeted multipotential therapeutic strategies

The Fas Death Signaling Pathway Connecting Reactive Oxygen Species Generation and FLICE Inhibitory Protein Down-Regulation

(2014) L. Wang et al.   JOURNAL OF IMMUNOLOGY

Brain energy depletion in a rodent model of diffuse traumatic brain injury is not prevented with administration of sodium lactate

(2011) Ruth Prieto et al.   BRAIN RESEARCH

Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis

(2011) Andrea Rasola et al.   CELL CALCIUM

Broad-spectrum neuroprotection against traumatic brain injury by agonism of peroxisome proliferator-activated receptors

(2011) Bridgette D. Semple et al.   EXPERIMENTAL NEUROLOGY

Post-Injury Administration of the Mitochondrial Permeability Transition Pore Inhibitor, NIM811, Is Neuroprotective and Improves Cognition after Traumatic Brain Injury in Rats

(2011) Ryan D. Readnower et al.   JOURNAL OF NEUROTRAUMA

The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore

(2011) Pinadda Varanyuwatana et al.   MITOCHONDRION

Distinctive characteristics and functions of multiple mitochondrial Ca2+ influx mechanisms

(2011) Shi Pan et al.   Science China-Life Sciences

Therapeutic hypothermia cardioprotection via Akt- and nitric oxide-mediated attenuation of mitochondrial oxidants

(2010) Zuo-Hui Shao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

Bcl-2 proteins and mitochondria—Specificity in membrane targeting for death

(2010) Jennefer Lindsay et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Glutamate-Mediated Injury in Focal Cerebral Ischemia: The Excitotoxin Hypothesis Revised

(2010) Konstantin-Alexander Hossmann   BRAIN PATHOLOGY

Hyperbaric oxygen preconditioning reduces ischemia–reperfusion injury by stimulating autophagy in neurocyte

(2010) Yong-Chun Wang et al.   BRAIN RESEARCH

Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments

(2010) James J Donkin et al.   CURRENT OPINION IN NEUROLOGY

Resistance to Caspase-Independent Cell Death Requires Persistence of Intact Mitochondria

(2010) Stephen W.G. Tait et al.   DEVELOPMENTAL CELL

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Mitochondrial Inner Membrane GTPase, Optic Atrophy 1 (Opa1), Restores Mitochondrial Morphology and Promotes Neuronal Survival following Excitotoxicity

(2010) Arezu Jahani-Asl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Poly(ADP-ribose) Polymerase (PARP)-1-independent Apoptosis-inducing Factor (AIF) Release and Cell Death Are Induced by Eleostearic Acid and Blocked by α-Tocopherol and MEK Inhibition

(2010) Kazunari Kondo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic manipulators: a well founded strategy to combat mitochondrial dysfunction

(2010) Saskia Koene et al.   JOURNAL OF INHERITED METABOLIC DISEASE

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria

(2010) Yehudit Zaltsman et al.   NATURE CELL BIOLOGY

Antioxidant therapies for traumatic brain injury

(2010) Edward D. Hall et al.   Neurotherapeutics

Cell death mechanisms and modulation in traumatic brain injury

(2010) Bogdan A. Stoica et al.   Neurotherapeutics

Apoptotic cell death "Nixed" by an ER-mitochondrial necrotic pathway

(2010) R. N. Kitsis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characteristics and possible functions of mitochondrial Ca2+ transport mechanisms

(2009) Thomas E. Gunter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis

(2009) Zachary T. Schug et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study

(2009) Clare N. Gallagher et al.   BRAIN

Detrimental consequences of brain injury on peripheral cells

(2009) Anna Catania et al.   BRAIN BEHAVIOR AND IMMUNITY

Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death

(2009) Julia Grohm et al.   BRAIN BEHAVIOR AND IMMUNITY

Direct inhibition of the mitochondrial permeability transition pore: A possible mechanism for better neuroprotective effects of allopregnanolone over progesterone

(2009) Iqbal Sayeed et al.   BRAIN RESEARCH

Oxidative Stress-Induced Necrotic Cell Death via Mitochondira-Dependent Burst of Reactive Oxygen Species

(2009) Kyungsun Choi et al.   CURRENT NEUROVASCULAR RESEARCH

The optimal dosage and window of opportunity to maintain mitochondrial homeostasis following traumatic brain injury using the uncoupler FCCP

(2009) Jignesh D. Pandya et al.   EXPERIMENTAL NEUROLOGY

Crosstalk signaling between mitochondrial Ca2+ and ROS

(2009) Robert et al.   Frontiers in Bioscience-Landmark

Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration

(2009) Alejandro F. De Nicola et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Cleavage of Bid by Executioner Caspases Mediates Feed Forward Amplification of Mitochondrial Outer Membrane Permeabilization during Genotoxic Stress-induced Apoptosis in Jurkat Cells

(2009) Shary N. Shelton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substance P is Associated with the Development of Brain Edema and Functional Deficits after Traumatic Brain Injury

(2009) James J Donkin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos)

(2009) Yingfei Wang et al.   JOURNAL OF NEUROCHEMISTRY

Effect of Short Periods of Normobaric Hyperoxia on Local Brain Tissue Oxygenation and Cerebrospinal Fluid Oxidative Stress Markers in Severe Traumatic Brain Injury

(2009) Ava M. Puccio et al.   JOURNAL OF NEUROTRAUMA

Combination Therapies for Traumatic Brain Injury: Prospective Considerations

(2009) Susan Margulies et al.   JOURNAL OF NEUROTRAUMA

Early Mitochondrial Dysfunction after Cortical Contusion Injury

(2009) Lesley K. Gilmer et al.   JOURNAL OF NEUROTRAUMA

Metabolic Acetate Therapy for the Treatment of Traumatic Brain Injury

(2009) Peethambaran Arun et al.   JOURNAL OF NEUROTRAUMA

Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: A long-term follow-up

(2009) Yi Zuo et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Mitochondrial gateways to cancer

(2009) Lorenzo Galluzzi et al.   MOLECULAR ASPECTS OF MEDICINE

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

(2009) Angela M Brennan et al.   NATURE NEUROSCIENCE

Upregulation of Phagocyte-Derived Catecholamines Augments the Acute Inflammatory Response

(2009) Michael A. Flierl et al.   PLoS One

MAM: more than just a housekeeper

(2009) Teruo Hayashi et al.   TRENDS IN CELL BIOLOGY

The changing shape of mitochondrial apoptosis

(2009) Michał Wasilewski et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Brain metabolic and hemodynamic effects of cyclosporin A after human severe traumatic brain injury: a microdialysis study

(2008) Anna Teresa Mazzeo et al.   ACTA NEUROCHIRURGICA

The Identity and Regulation of the Mitochondrial Permeability Transition Pore

(2008) Magdalena Juhaszova et al.   Annals of the New York Academy of Sciences

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Inhibition of caspase-3 activity and activation by protein glutathionylation

(2008) Zhishan Huang et al.   BIOCHEMICAL PHARMACOLOGY

Neuroprotective effect of hyperbaric oxygen therapy in brain injury is mediated by preservation of mitochondrial membrane properties

(2008) Eilam Palzur et al.   BRAIN RESEARCH

Necroptosis: A Specialized Pathway of Programmed Necrosis

(2008) Lorenzo Galluzzi et al.   CELL

Contributions to Bax insertion and oligomerization of lipids of the mitochondrial outer membrane

(2008) S Lucken-Ardjomande et al.   CELL DEATH AND DIFFERENTIATION

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism

Antioxidants and Free Radical Scavengers for the Treatment Of Stroke, Traumatic Brain Injury and Aging

(2008) J. Weber et al.   CURRENT MEDICINAL CHEMISTRY

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL

UCP-mediated free fatty acid uncoupling of isolated cortical mitochondria from fasted animals: Correlations to dietary modulations

(2008) Laurie M. Davis et al.   EPILEPSIA

Neuroprotective effect of Ro5-4864 following brain injury

(2008) Jean F. Soustiel et al.   EXPERIMENTAL NEUROLOGY

Mechanism of Mitochondrial Glutathione-Dependent Hepatocellular Susceptibility to TNF Despite NF-κB Activation

(2008) Montserrat Marí et al.   GASTROENTEROLOGY

Mitochondrial dynamics and apoptosis

(2008) D.-F. Suen et al.   GENES & DEVELOPMENT

Shaping mitochondria: The complex posttranslational regulation of the mitochondrial fission protein DRP1

(2008) Ansgar Santel et al.   IUBMB LIFE

The Mitochondrial Phosphate Carrier Interacts with Cyclophilin D and May Play a Key Role in the Permeability Transition

(2008) Anna W. C. Leung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specific Targeting of Pro-Death NMDA Receptor Signals with Differing Reliance on the NR2B PDZ Ligand

(2008) F. X. Soriano et al.   JOURNAL OF NEUROSCIENCE

Fasting is neuroprotective following traumatic brain injury

(2008) Laurie M. Davis et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Classification of Traumatic Brain Injury for Targeted Therapies

(2008) Kathryn E. Saatman et al.   JOURNAL OF NEUROTRAUMA

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(2008) Kathryn Beauchamp et al.   MOLECULAR MEDICINE

Cellular Stress Response: A Novel Target for Chemoprevention and Nutritional Neuroprotection in Aging, Neurodegenerative Disorders and Longevity

(2008) Vittorio Calabrese et al.   NEUROCHEMICAL RESEARCH

Liver Kupffer cells control the magnitude of the inflammatory response in the injured brain and spinal cord

(2008) Sandra J. Campbell et al.   NEUROPHARMACOLOGY

Postsynaptic mechanisms of excitotoxicity: Involvement of postsynaptic density proteins, radicals, and oxidant molecules

(2008) J.P. Forder et al.   NEUROSCIENCE

Necroptosis contributes to the NMDA-induced excitotoxicity in rat’s cultured cortical neurons

(2008) Yanli Li et al.   NEUROSCIENCE LETTERS

Multifunctional drug treatment in neurotrauma

(2008) Bogdan Stoica et al.   Neurotherapeutics

Multifunctional drugs for head injury

(2008) Robert Vink et al.   Neurotherapeutics

Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA

(2008) Philippe A. Parone et al.   PLoS One

Bcl-2 Protein Family Members: Versatile Regulators of Calcium Signaling in Cell Survival and Apoptosis

(2007) Yiping Rong et al.   Annual Review of Physiology

Attenuation of acute mitochondrial dysfunction after traumatic brain injury in mice by NIM811, a non-immunosuppressive cyclosporin A analog

(2007) L.H. Mbye et al.   EXPERIMENTAL NEUROLOGY

The role of Bax in glutamate-induced nerve cell death

(2003) Richard Dargusch et al.   JOURNAL OF NEUROCHEMISTRY