Post-Injury Administration of the Mitochondrial Permeability Transition Pore Inhibitor, NIM811, Is Neuroprotective and Improves Cognition after Traumatic Brain Injury in Rats

Membrane potential-related effect of calcium on reactive oxygen species generation in isolated brain mitochondria

(2010) Zsofia Komary et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury

(2010) Ryan D. Readnower et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Diffuse Brain Injury Elevates Tonic Glutamate Levels and Potassium-Evoked Glutamate Release in Discrete Brain Regions at Two Days Post-Injury: An Enzyme-Based Microelectrode Array Study

(2010) Jason M. Hinzman et al.   JOURNAL OF NEUROTRAUMA

Calpain as a therapeutic target in traumatic brain injury

(2010) Kathryn E. Saatman et al.   Neurotherapeutics

Mitochondrial calcium and the permeability transition in cell death

(2009) John J. Lemasters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The role of mitochondrial transition pore, and its modulation, in traumatic brain injury and delayed neurodegeneration after TBI

(2009) Anna Teresa Mazzeo et al.   EXPERIMENTAL NEUROLOGY

Cyclosporine A for neuroprotection: establishing dosing guidelines for safe and effective use

(2009) Aaron M Cook et al.   Expert Opinion On Drug Safety

Biochemical, Structural, and Biomarker Evidence for Calpain-Mediated Cytoskeletal Change After Diffuse Brain Injury Uncomplicated by Contusion

(2009) Melissa J. McGinn et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Early Mitochondrial Dysfunction after Cortical Contusion Injury

(2009) Lesley K. Gilmer et al.   JOURNAL OF NEUROTRAUMA

Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition

(2008) Magnus J. Hansson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuroprotective Effects of Tempol, a Catalytic Scavenger of Peroxynitrite-Derived Free Radicals, in a Mouse Traumatic Brain Injury Model

(2008) Ying Deng-Bryant et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Comparative Neuroprotective Effects of Cyclosporin a and NIM811, a Nonimmunosuppressive Cyclosporin a Analog, following Traumatic Brain Injury

(2008) Lamin Han Mbye et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Fasting is neuroprotective following traumatic brain injury

(2008) Laurie M. Davis et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Dietary Choline Supplementation Improves Behavioral, Histological, and Neurochemical Outcomes in a Rat Model of Traumatic Brain Injury

(2008) Maria V. Guseva et al.   JOURNAL OF NEUROTRAUMA

Attenuation of acute mitochondrial dysfunction after traumatic brain injury in mice by NIM811, a non-immunosuppressive cyclosporin A analog

(2007) L.H. Mbye et al.   EXPERIMENTAL NEUROLOGY