IFN-γ synergistically enhances LPS signalling in alveolar macrophages from COPD patients and controls by corticosteroid-resistant STAT1 activation

Resveratrol Impairs the Release of Steroid-resistant Cytokines from Bacterial Endotoxin-Exposed Alveolar Macrophages in Chronic Obstructive Pulmonary Disease

(2011) Jürgen Knobloch et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Discovery of the Macrocycle 11-(2-Pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (SB1518), a Potent Janus Kinase 2/Fms-Like Tyrosine Kinase-3 (JAK2/FLT3) Inhibitor for the Treatment of Myelofibrosis and Lymphoma

(2011) Anthony D. William et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synergistic Effects of p38 Mitogen-Activated Protein Kinase Inhibition with a Corticosteroid in Alveolar Macrophages from Patients with Chronic Obstructive Pulmonary Disease

(2011) J. Armstrong et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A novel technique to explore the functions of bronchial mucosal T cells in chronic obstructive pulmonary disease: application to cytotoxicity and cytokine immunoreactivity

(2010) M. W. Lethbridge et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Budesonide enhances Toll-like receptor 2 expression in activated bronchial epithelial cells

(2010) Ida von Scheele et al.   INHALATION TOXICOLOGY

Human rhinovirus proteinase 2A induces TH1 and TH2 immunity in patients with chronic obstructive pulmonary disease

(2010) Manisha Singh et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TNF  and IFN  Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF- B, and the Transcriptional Coactivator CREB-binding Protein

(2010) D. L. Clarke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhaled Corticosteroids in COPD: A Controversy

(2010) Peter J. Barnes   RESPIRATION

Lymphoid Follicle Cells in Chronic Obstructive Pulmonary Disease Overexpress the Chemokine Receptor CXCR3

(2009) Steven G. Kelsen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: results from a randomised, double-blind, placebo-controlled trial

(2009) J H Coombs et al.   ANNALS OF THE RHEUMATIC DISEASES

Glucocorticoid sensitivity of lipopolysaccharide-stimulated chronic obstructive pulmonary disease alveolar macrophages

(2009) J. Armstrong et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Gene modulation and immunoregulatory roles of Interferonγ

(2009) Banishree Saha et al.   CYTOKINE

Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms

(2009) Xiaoyu Hu et al.   IMMUNOLOGICAL REVIEWS

Smoking-Dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of Chronic Obstructive Pulmonary Disease

(2009) R. Shaykhiev et al.   JOURNAL OF IMMUNOLOGY

IL-8 Dictates Glycosaminoglycan Binding and Stability of IL-18 in Cystic Fibrosis

(2009) E. P. Reeves et al.   JOURNAL OF IMMUNOLOGY

Peripheral T Cell Functions Correlate with the Severity of Chronic Obstructive Pulmonary Disease

(2009) X. Zhu et al.   JOURNAL OF IMMUNOLOGY

Differential gene expression analysis in human monocyte-derived macrophages: Impact of cigarette smoke on host defence

(2009) Ian Doyle et al.   MOLECULAR IMMUNOLOGY

Tc2 Response at the Onset of COPD Exacerbations

(2008) Demosthenes Makris et al.   CHEST

Cigarette smoke extract induced cytokine and chemokine gene expression changes in COPD macrophages

(2008) Lauren Kent et al.   CYTOKINE

IFNγ signaling—Does it mean JAK–STAT?

(2008) Daniel J. Gough et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Infection in the Pathogenesis and Course of Chronic Obstructive Pulmonary Disease

(2008) Sanjay Sethi et al.   NEW ENGLAND JOURNAL OF MEDICINE