Metformin inhibits HMGB1 release in LPS-treated RAW 264.7 cells and increases survival rate of endotoxaemic mice

Ghrelin Protects against Experimental Sepsis by Inhibiting High-Mobility Group Box 1 Release and by Killing Bacteria

(2014) A. Chorny et al.   JOURNAL OF IMMUNOLOGY

Adenosine 5'-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype

(2014) D. Sag et al.   JOURNAL OF IMMUNOLOGY

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

HMGB1 in systemic lupus Erythematosus: Its role in cutaneous lesions development

(2010) D.A. Abdulahad et al.   AUTOIMMUNITY REVIEWS

The role of HMGB1 in the pathogenesis of rheumatic disease

(2010) Ulf Andersson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

HMGB proteins: Interactions with DNA and chromatin

(2010) Michal Štros   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Metformin: A Therapeutic Opportunity in Breast Cancer

(2010) A. M. Gonzalez-Angulo et al.   CLINICAL CANCER RESEARCH

JAK2 inhibition prevents innate immune responses and rescues animals from sepsis

(2010) Geber Peña et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Carbon Monoxide From CORM-2 Reduces HMGB1 Release Through Regulation of IFN-β/JAK2/STAT-1/INOS/NO Signaling But Not COX-2 in TLR-Activated Macrophages

(2010) Konstantin Tsoyi et al.   SHOCK

Metformin decreases angiogenesis via NF-κB and Erk1/2/Erk5 pathways by increasing the antiangiogenic thrombospondin-1

(2009) Bee K. Tan et al.   CARDIOVASCULAR RESEARCH

Co-treatment with deoxycholic acid and azoxymethane accelerates secretion of HMGB1 in IEC6 intestinal epithelial cells

(2009) K. Fujii et al.   CELL PROLIFERATION

Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis

(2009) N. Nath et al.   JOURNAL OF IMMUNOLOGY

Heme-Oxygenase-1 Induction and Carbon Monoxide-Releasing Molecule Inhibit Lipopolysaccharide (LPS)-Induced High-Mobility Group Box 1 Release in Vitro and Improve Survival of Mice in LPS- and Cecal Ligation and Puncture-Induced Sepsis Model in Vivo

(2009) K. Tsoyi et al.   MOLECULAR PHARMACOLOGY

Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury

(2008) Xia Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid, CKD712, in cells activated with lipopolysacchride

(2008) Konstantin Tsoyi et al.   CELLULAR SIGNALLING

HMGB1 as a predictor of organ dysfunction and outcome in patients with severe sepsis

(2008) Sari Karlsson et al.   INTENSIVE CARE MEDICINE