How accurate is in vitro prediction of carcinogenicity?

Further analysis of Ames-negative rodent carcinogens that are only genotoxic in mammalian cells in vitro at concentrations exceeding 1 mM, including retesting of compounds of concern

(2010) D. Kirkland et al.   MUTAGENESIS

Analysis of published data for top concentration considerations in mammalian cell genotoxicity testing

(2010) James M. Parry et al.   MUTAGENESIS

A pre-validation transferability study of the GreenScreen HC GADD45a-GFP assay with a metabolic activation system (S9)

(2010) Nicholas Billinton et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Epigenetics and chemical safety assessment

(2010) Matthew J. LeBaron et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Integration of Mutation and Chromosomal Damage Endpoints into 28-Day Repeat Dose Toxicology Studies

(2010) Stephen D. Dertinger et al.   TOXICOLOGICAL SCIENCES

Comparison of the Ames II and traditional Ames test responses with respect to mutagenicity, strain specificities, need for metabolism and correlation with rodent carcinogenicity

(2009) M. Kamber et al.   MUTAGENESIS

Analysis of 75 marketed pharmaceuticals using the GADD45a-GFP ‘GreenScreen HC’ genotoxicity assay

(2009) Paul W. Hastwell et al.   MUTAGENESIS

Intralaboratory and interlaboratory evaluation of the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay

(2009) Ting Hu et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Further development of the EpiDerm™ 3D reconstructed human skin micronucleus (RSMN) assay

(2009) Greg C. Mun et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development

(2009) Walter M.A. Westerink et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

GADD45a-GFP GreenScreen HC assay results for the ECVAM recommended lists of genotoxic and non-genotoxic chemicals for assessment of new genotoxicity tests

(2009) Louise Birrell et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

(2009) Lya G. Hernández et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

ECVAM retrospective validation of in vitro micronucleus test (MNT)

(2008) R. Corvi et al.   MUTAGENESIS

The comet assay: topical issues

(2008) A. R. Collins et al.   MUTAGENESIS

Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test

(2008) E. Lorge et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test

(2008) Michael D. Fellows et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: An enabling study for independent validation as an alternative method

(2008) Nicholas Billinton et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: A follow-up to an ECVAM workshop

(2008) David Kirkland et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Update on genotoxicity and carcinogenicity testing of 472 marketed pharmaceuticals

(2008) Giovanni Brambilla et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Understanding Genetic Toxicity Through Data Mining: The Process of Building Knowledge by Integrating Multiple Genetic Toxicity Databases

(2008) C. Yang et al.   TOXICOLOGY MECHANISMS AND METHODS

Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay

(2007) Steven M. Bryce et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS