Inhibitor of PI3Kγ ameliorates TNBS-induced colitis in mice by affecting the functional activity of CD4+CD25+FoxP3+ regulatory T cells

Interleukin-10 production by tumor infiltrating macrophages plays a role in Human Papillomavirus 16 tumor growth

(2012) Aline Bolpetti et al.   BMC IMMUNOLOGY

The absence of functional PI3Kγ prevents leukocyte recruitment and ameliorates DSS-induced colitis in mice

(2010) Willemijn A. van Dop et al.   IMMUNOLOGY LETTERS

PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors: Figure 1.

(2010) Matthias Merkenschlager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells

(2010) Weiming Ouyang et al.   NATURE IMMUNOLOGY

Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis

(2009) Pallavi Garg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-κB

(2009) Lirlândia P. Sousa et al.   BIOCHEMICAL PHARMACOLOGY

Phosphatidylinositol 3-Kinase γ Inhibition Ameliorates Inflammation and Tumor Growth in a Model of Colitis-Associated Cancer

(2009) Ana González–García et al.   GASTROENTEROLOGY

The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment

(2009) Greg M. Delgoffe et al.   IMMUNITY

Inhibition of Phosphoinositide 3-Kinase Ameliorates Dextran Sodium Sulfate-Induced Colitis in Mice

(2009) X.-d. Peng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Minocycline attenuates experimental colitis in mice by blocking expression of inducible nitric oxide synthase and matrix metalloproteinases

(2009) Tien-Yu Huang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The relevance of kinin B1receptor upregulation in a mouse model of colitis

(2008) D B Hara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulatory T cells in inflammatory bowel disease

(2008) Elisa K Boden et al.   CURRENT OPINION IN GASTROENTEROLOGY

Special regulatory T-cell review: regulatory T cells and the intestinal tract – patrolling the frontier

(2008) Ana Izcue et al.   IMMUNOLOGY

What is the optimal therapy for severe ulcerative colitis?

(2008) Richard P. MacDermott et al.   INFLAMMATORY BOWEL DISEASES

The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+cells

(2008) Sokol Haxhinasto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice

(2008) Allisson Freire Bento et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neutralizing Anti-Vascular Endothelial Growth Factor (VEGF) Antibody Reduces Severity of Experimental Ulcerative Colitis in Rats: Direct Evidence for the Pathogenic Role of VEGF

(2008) G. Tolstanova et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR

(2008) S. Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dexamethasone reduces food intake, weight gain and the hypothalamic 5-HT concentration and increases plasma leptin in rats

(2007) Jeong Won Jahng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY