Current issues surrounding the definition of trans-fatty acids: implications for health, industry and food labels

Milk Enriched with Conjugated Linoleic Acid Fails to Alter Blood Lipids or Body Composition in Moderately Overweight, Borderline Hyperlipidemic Individuals

(2013) Sudha Venkatramanan et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

CLA Does Not Impair Endothelial Function and Decreases Body Weight as Compared with Safflower Oil in Overweight and Obese Male Subjects

(2013) Maria Pfeuffer et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Cross-sectional study of conjugated linoleic acid in adipose tissue and risk of diabetes

(2012) Nelsy Castro-Webb et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Intake of ruminant trans fatty acids and changes in body weight and waist circumference

(2012) C P Hansen et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Levels of Plasma trans-Fatty Acids in Non-Hispanic White Adults in the United States in 2000 and 2009

(2012) Hubert W. Vesper   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Change in Conjugated Linoleic Acid Concentration in Blood of Japanese Fed a Conjugated Linoleic Acid Diet

(2012) Kenta SATO et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Effect of supplementation with an 80:20cis9,trans11 conjugated linoleic acid blend on the human platelet proteome

(2012) Eva-Maria Bachmair et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The intestinal bioavailability of vaccenic acid and activation of peroxisome proliferator-activated receptor-α and -γ in a rodent model of dyslipidemia and the metabolic syndrome

(2012) Ye Wang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Human health effects of conjugated linoleic acid from milk and supplements

(2012) Tracy A. McCrorie et al.   NUTRITION RESEARCH REVIEWS

Effects of Ruminant trans Fatty Acids on Cardiovascular Disease and Cancer: A Comprehensive Review of Epidemiological, Clinical, and Mechanistic Studies

(2012) Sarah K. Gebauer et al.   Advances in Nutrition

Randomized controlled study of the effect of a butter naturally enriched in trans fatty acids on blood lipids in healthy women

(2011) Émilie Lacroix et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Prospective Study of Diet and Venous Thromboembolism in US Women and Men

(2011) R. Varraso et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Could dietary trans fatty acids induce movement disorders? Effects of exercise and its influence on Na+K+-ATPase and catalase activity in rat striatum

(2011) A.M. Teixeira et al.   BEHAVIOURAL BRAIN RESEARCH

Deleterious impact of elaidic fatty acid on ABCA1-mediated cholesterol efflux from mouse and human macrophages

(2011) Natalie Fournier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Trans-10, cis-12-conjugated linoleic acid modulates NF-κB activation and TNF-α production in porcine peripheral blood mononuclear cells via a PPARγ-dependent pathway

(2011) Dong-In Kim et al.   BRITISH JOURNAL OF NUTRITION

Conjugated linoleic acid induces hepatic expression of fibroblast growth factor 21 through PPAR-α

(2011) Jie Yu et al.   BRITISH JOURNAL OF NUTRITION

Conjugated linoleic acid-induced apoptosis in mouse mammary tumor cells is mediated by both G protein coupled receptor-dependent activation of the AMP-activated protein kinase pathway and by oxidative stress

(2011) Yung-Chung Hsu et al.   CELLULAR SIGNALLING

Bovine milk fat enriched in conjugated linoleic and vaccenic acids attenuates allergic dermatitis in mice

(2011) X. Sun et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Time-dependent effects of safflower oil to improve glycemia, inflammation and blood lipids in obese, post-menopausal women with type 2 diabetes: A randomized, double-masked, crossover study

(2011) Michelle L. Asp et al.   CLINICAL NUTRITION

Trans-10, cis-12-conjugated linoleic acid attenuates tumor necrosis factor-α production by lipopolysaccharide-stimulated porcine peripheral blood mononuclear cells through induction of interleukin-10

(2011) Keun-Hwa Kim et al.   CYTOKINE

Trans-10, cis-12 conjugated linoleic acid and the PPAR-γ agonist rosiglitazone attenuate lipopolysaccharide-induced TNF-α production by bovine immune cells

(2011) M.C. Perdomo et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Consumption of industrial and ruminant trans fatty acids and risk of coronary heart disease: a systematic review and meta-analysis of cohort studies

(2011) N T Bendsen et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

The efficacy of long-term conjugated linoleic acid (CLA) supplementation on body composition in overweight and obese individuals: a systematic review and meta-analysis of randomized clinical trials

(2011) Igho J. Onakpoya et al.   EUROPEAN JOURNAL OF NUTRITION

Nutrigenomics of hepatic steatosis in a feline model: effect of monosodium glutamate, fructose, and Trans-fat feeding

(2011) Kate S. Collison et al.   Genes and Nutrition

Dietary conjugated linoleic acid and long-chainn-3 fatty acids in mammary and prostate cancer protection: a review

(2011) Verónica M. Heinze et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Conjugated linoleic acid isomers may diminish human macrophages adhesion to endothelial surface

(2011) Ewa Stachowska et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Conjugated Linoleic Acid Regulates Phosphorylation of PPARγ by Modulation of ERK 1/2 and p38 Signaling in Human Macrophages/Fatty Acid-Laden Macrophages

(2011) Ewa Stachowska et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A 4-Week Repeated Oral Dose Toxicity Study of Dairy Fat Naturally Enriched in Vaccenic, Rumenic and α-Linolenic Acids in Rats

(2011) Arturo Anadón et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The effect of conjugated linoleic acid, a natural trans fat from milk and meat, on human blood pressure: results from a randomized crossover feeding study

(2011) M F Engberink et al.   JOURNAL OF HUMAN HYPERTENSION

Effect of Functional Buffalo Cheese on Fatty Acid Profile and Oxidative Status of Liver and Intestine of Mice

(2011) Carina P. Van Nieuwenhove et al.   JOURNAL OF MEDICINAL FOOD

Differential Effects of the trans-18:1 Isomer Profile of Partially Hydrogenated Vegetable Oils on Cholesterol and Lipoprotein Metabolism in Male F1B Hamsters

(2011) Jana Kraft et al.   JOURNAL OF NUTRITION

A High Intake of trans Fatty Acids Has Little Effect on Markers of Inflammation and Oxidative Stress in Humans

(2011) Liesbeth A. Smit et al.   JOURNAL OF NUTRITION

Conjugated Linoleic Acid Supplementation for 8 Weeks Does Not Affect Body Composition, Lipid Profile, or Safety Biomarkers in Overweight, Hyperlipidemic Men

(2011) Shama V. Joseph et al.   JOURNAL OF NUTRITION

Intake of trans fatty acids during gestation and lactation leads to hypothalamic inflammation via TLR4/NFκBp65 signaling in adult offspring

(2011) Gustavo D. Pimentel et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Conjugated linoleic acid improves blood pressure by increasing adiponectin and endothelial nitric oxide synthase activity

(2011) Vanessa DeClercq et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Trans-10, cis-12 conjugated linoleic acid decreases de novo lipid synthesis in human adipocytes

(2011) Thomas Obsen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

JNK Inhibition by SP600125 Attenuates trans-10, cis-12 Conjugated Linoleic Acid-Mediated Regulation of Inflammatory and Lipogenic Gene Expression

(2011) Kristina Martinez et al.   LIPIDS

Fatty acid distribution of cord and maternal blood in human pregnancy: special focus on individual trans fatty acids and conjugated linoleic acids

(2011) Uta Enke et al.   Lipids in Health and Disease

Influence of in vitro supplementation with lipids from conventional and Alpine milk on fatty acid distribution and cell growth of HT-29 cells

(2011) Christian Degen et al.   Lipids in Health and Disease

Comparison of the impact of trans fatty acids from ruminant and industrial sources on surrogate markers of cholesterol homeostasis in healthy men

(2011) Marie-Ève Labonté et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Nutrient biomarker patterns, cognitive function, and MRI measures of brain aging

(2011) G. L. Bowman et al.   NEUROLOGY

The intake of high fat diet with different trans fatty acid levels differentially induces oxidative stress and non alcoholic fatty liver disease (NAFLD) in rats

(2011) Madiha Dhibi et al.   Nutrition & Metabolism

Diets high in conjugated linoleic acid from pasture-fed cattle did not alter markers of health in young women

(2011) Andrew W. Brown et al.   NUTRITION RESEARCH

Trans Fatty Acids Induce Vascular Inflammation and Reduce Vascular Nitric Oxide Production in Endothelial Cells

(2011) Naomi G. Iwata et al.   PLoS One

Acylpeptide Hydrolase Inhibition as Targeted Strategy to Induce Proteasomal Down-Regulation

(2011) Gianna Palmieri et al.   PLoS One

A high intake of industrial or ruminant trans fatty acids does not affect the plasma proteome in healthy men

(2011) Baukje de Roos et al.   PROTEOMICS

Inter-organ proteomic analysis reveals insights into the molecular mechanisms underlying the anti-diabetic effects of cis-9, trans-11-conjugated linoleic acid in ob/ob mice

(2011) Vanessa Rungapamestry et al.   PROTEOMICS

Conjugated linoleic acid in adipose tissue and risk of myocardial infarction

(2010) Liesbeth A Smit et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Food sources of individual plasma phospholipid trans fatty acid isomers: the Cardiovascular Health Study

(2010) Renata Micha et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Production of conjugated linoleic acid and conjugated linolenic acid isomers by Bifidobacterium species

(2010) Lara Gorissen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Modulation of lipid droplet size and lipid droplet proteins by trans-10,cis-12 conjugated linoleic acid parallels improvements in hepatic steatosis in obese, insulin-resistant rats

(2010) Danielle M. Stringer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Dietary conjugated linoleic acid and n-3 polyunsaturated fatty acids in inflammatory bowel disease

(2010) Josep Bassaganya-Riera et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Attenuation of 12-O-Tetradecanoylphorbol-13-acetate (TPA)-Induced Gap Junctional Intercellular Communication (GJIC) Inhibition in MCF-10A Cells by c9,t11-Conjugated Linoleic Acid

(2010) Md. Abdur Rakib et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Interaction between dietary conjugated linoleic acid and calcium supplementation affecting bone and fat mass

(2010) Yooheon Park et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Different mechanisms of cis-9,trans-11- and trans-10,cis-12- conjugated linoleic acid affecting lipid metabolism in 3T3-L1 cells

(2010) Jia-jie Zhai et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Activated AMPK and prostaglandins are involved in the response to conjugated linoleic acid and are sufficient to cause lipid reductions in adipocytes

(2010) Shan Jiang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Dietary t10,c12-CLA but not c9,t11 CLA Reduces Adipocyte Size in the Absence of Changes in the Adipose Renin–Angiotensin System in fa/fa Zucker Rats

(2010) Vanessa DeClercq et al.   LIPIDS

Influence of diet enriched with conjugated linoleic acids on their distribution in tissues of rats with DMBA induced tumors

(2010) Agnieszka Białek et al.   Lipids in Health and Disease

Trans-10, cis-12 conjugated linoleic acid inhibits skeletal muscle differentiation and GLUT4 expression independently from NF-κB activation

(2010) Pascal P. H. Hommelberg et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effects of trans -10, cis -12 CLA on liver size and fatty acid oxidation under energy restriction conditions in hamsters

(2010) Arrate Lasa et al.   NUTRITION

Increased hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid in combination with trans-11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR:LA-cp rat

(2010) M Miriam Jacome-Sosa et al.   Nutrition & Metabolism

Effect of a High Intake of Conjugated Linoleic Acid on Lipoprotein Levels in Healthy Human Subjects

(2010) Anne J. Wanders et al.   PLoS One

Effect of Animal and Industrial Trans Fatty Acids on HDL and LDL Cholesterol Levels in Humans – A Quantitative Review

(2010) Ingeborg A. Brouwer et al.   PLoS One

Conjugated linoleic acid and inflammatory cell signalling

(2010) C.M. Reynolds et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Trans-10, cis-12 conjugated linoleic acid directly enhances the chemotactic activity of porcine peripheral blood polymorphonuclear neutrophillic leukocytes by activating F-actin polymerization in vitro

(2010) Jooyae Paek et al.   RESEARCH IN VETERINARY SCIENCE

Dairy and industrial sources of trans fat do not impair peripheral insulin sensitivity in overweight women

(2009) Anne-Laure Tardy et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Dietary supplementation with cis-9,trans-11 conjugated linoleic acid and aortic stiffness in overweight and obese adults

(2009) Ivonne Sluijs et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

A meta-analysis of the effects of conjugated linoleic acid on fat-free mass in humans

(2009) Dale A. Schoeller et al.   Applied Physiology Nutrition and Metabolism

trans-Fatty acid consumption and its association with distal colorectal cancer in the North Carolina Colon Cancer Study II

(2009) Lisa C. Vinikoor et al.   CANCER CAUSES & CONTROL

Activation of the AMP-activated protein kinase–p38 MAP kinase pathway mediates apoptosis induced by conjugated linoleic acid in p53-mutant mouse mammary tumor cells

(2009) Yung-Chung Hsu et al.   CELLULAR SIGNALLING

Bioaccessibility of fatty acids from conjugated linoleic acid-enriched milk and milk emulsions studied in a dynamic in vitro gastrointestinal model

(2009) Rachel Gervais et al.   INTERNATIONAL DAIRY JOURNAL

Trans-11 Vaccenic Acid Reduces Hepatic Lipogenesis and Chylomicron Secretion in JCR:LA-cp Rats

(2009) Ye Wang et al.   JOURNAL OF NUTRITION

Dietary Vaccenic Acid Has Antiatherogenic Effects in LDLr−/− Mice

(2009) Chantal M. C. Bassett et al.   JOURNAL OF NUTRITION

Antiobesity mechanisms of action of conjugated linoleic acid

(2009) Arion Kennedy et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis

(2009) Melissa S. Ashwell et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Fatty acids and breast cancer: Sensitization to treatments and prevention of metastatic re-growth

(2009) Philippe Bougnoux et al.   PROGRESS IN LIPID RESEARCH

A Prospective Study of Trans-Fatty Acid Levels in Blood and Risk of Prostate Cancer

(2008) J. E. Chavarro et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Commentary: Ruminant trans fatty acids and coronary heart disease--cause for concern?

(2008) D. Mozaffarian   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Enzymatic Synthesis of Structured Triacylglycerols Containing CLA Isomers Starting from sn-1,3-Diacylglycerols

(2008) Silvia Maurelli et al.   JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY

Conjugated linoleic acid content of human plasma

(2008) Spiros N Zlatanos et al.   Lipids in Health and Disease