Article
Fisheries
D. Hermsen, D. B. Van de Waal, S. A. J. Declerck, J. A. J. Verreth, M. C. J. Verdegem
Summary: This study found that shrimp can obtain additional LC-PUFA from the pond's primary production in semi-intensive shrimp ponds, rather than solely relying on feed. Achieving a balance between LC-PUFA contribution through formulated feed and natural production can lead to sustainable shrimp farming.
AQUACULTURE NUTRITION
(2021)
Article
Medicine, General & Internal
Marina Ivanisevic, Marina Horvaticek, Karlo Delmis, Josip Delmis
Summary: This study found that supplementation with DHA and EPA in pregnant women with type 1 diabetes can increase the concentration and proportions of n-3 PUFAs in maternal and fetal blood, while decreasing the proportion of n-6 PUFAs.
ANNALS OF MEDICINE
(2021)
Article
Environmental Sciences
Alexandra Marques, Paula Canada, Catia Costa, Ana Basto, Fatima Piloto, Maria Antonia Salgado, Helena Abreu, Jorge Dias, Luisa M. P. Valente
Summary: To replace traditional fish oil, different combinations of alternative marine lipid sources rich in n-3 LC-PUFA were evaluated in the diets for European sea bass. The study demonstrated that combining expensive sources of n-3 LC-PUFA with low-priced sustainable oils allows fortifying European sea bass flesh with EPA and DHA, without major textural changes.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Agricultural Engineering
Ajeet Singh Chauhan, Anil Kumar Patel, Chiu-Wen Chen, Jo-Shu Chang, Philippe Michaud, Cheng-Di Dong, Reeta Rani Singhania
Summary: Considering the increasing health concerns, urban population tends to adopt a healthy lifestyle and incorporate nutritional food supplements to mitigate common health risks. The consumption of omega-3 and omega-6 PUFAs is on the rise, thus alternative commercial production methods are being developed. Microbial sources are emerging platforms to meet the global demand for omega PUFAs. Marine oleaginous protist Aurantiochytrium sp. has been identified as a potential source for substantial production of DHA and SFA. The objective of this research was to enhance PUFA yield by optimizing glucose concentration and nitrogen ratio. The maximum lipid and DHA yield and content were achieved at 30 g/L glucose, while the relative PUFA content was highest at 10 g/L glucose, with remaining SFA potentially usable for biodiesel.
BIORESOURCE TECHNOLOGY
(2023)
Review
Food Science & Technology
Huali Ye, Yunyi Liu, Zhike Xu, Xin Wei
Summary: Glaucoma, a leading cause of irreversible vision loss worldwide, is influenced by various risk factors such as age, increased intraocular pressure, inflammation, oxidative stress, and ocular blood flow deficits. While lowering intraocular pressure is the current effective method for controlling glaucoma progression, it may not always provide satisfactory results due to inadequate response and ongoing retinal neural degeneration. Fish oil, a dietary supplement rich in omega-3 fatty acids, has been reported to benefit glaucoma patients; however, its efficiency and underlying mechanisms are still unclear. This review summarizes the roles of active ingredients in fish oil, including lowering intraocular pressure, regulating blood supply, alleviating inflammation, and reducing oxidative stress, in delaying the development of glaucoma and promoting clinical management.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Review
Cardiac & Cardiovascular Systems
Michelle D. Kelsey, Neha J. Pagidipati
Summary: There has been much debate surrounding the use of omega-3 fatty acids, EPA and DHA, for cardiovascular risk reduction. Recent trials have offered conflicting evidence, with some showing reduction in CV risk using EPA alone in select populations, while others demonstrate no benefit and potential side effects.
CURRENT CARDIOLOGY REPORTS
(2023)
Article
Cell Biology
Jing Chen, Esther A. Zaal, Celia R. Berkers, Rob Ruijtenbeek, Johan Garssen, Frank A. Redegeld
Summary: The study demonstrates that pretreating MM cells with DHA/EPA before bortezomib significantly enhances chemosensitivity by decreasing GSH levels and altering metabolism, highlighting the role of GSH degradation in overcoming drug resistance. RNA-seq results suggest the NRF2-ATF3/4-CHAC1 signaling pathway as central in GSH degradation and indicate potential connections to various pathways contributing to the tumor suppressive effect. The findings implicate GSH degradation as a promising therapeutic target in MM and provide new insights into combating bortezomib resistance.
Review
Biotechnology & Applied Microbiology
Samuel Rollin, Adarsha Gupta, Christopher M. M. Franco, Surinder Singh, Munish Puri
Summary: This study examines the techniques and importance of sustainable alternatives for the extraction and processing of nutritional oils. The findings suggest that adopting environmentally friendly alternatives can improve efficiency and reduce toxicity, thereby meeting global needs more effectively.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Nutrition & Dietetics
A. Lehner, K. Staub, L. Aldakak, P. Eppenberger, F. Ruehli, Robert D. Martin, N. Bender
Summary: The study found no significant association between DHA/EPA supplementation and cognitive performance of children born to pregnant and/or breastfeeding women who consumed fish oil supplements.
Article
Food Science & Technology
Alejandra Valencia-Naranjo, Luz M. Manjarres-Correa, Juliana Bermudez-Cardona
Summary: This study aimed to evaluate the changes in the concentrations of EPA and DHA in the erythrocytes and breast milk of lactating women after three months of supplementation. The study found low consumption of omega-3 food sources and low EPA and DHA content initially. After supplementation, there was a significant increase in DHA levels in both erythrocytes and breast milk, while EPA levels did not change significantly.
CURRENT RESEARCH IN FOOD SCIENCE
(2022)
Review
Food Science & Technology
Arti Kumari, Sunil Pabbi, Aruna Tyagi
Summary: Omega-3 fatty acids, particularly EPA and DHA, are essential for human health and must be obtained through diet or supplementation. Traditional sources include vegetable oils and fish, but concerns about sustainability and contamination have led to the exploration of alternative sources, such as microalgae. This review discusses strategies for enhancing EPA and DHA production in microalgae, including strain selection, cultivation optimization, and genetic engineering. These approaches pave the way for large-scale production of EPA and DHA to promote human health.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Medicinal
Adelaide Cupo, Simone Landi, Salvatore Morra, Genoveffa Nuzzo, Carmela Gallo, Emiliano Manzo, Angelo Fontana, Giuliana D'Ippolito
Summary: This study investigates the cultivation of marine diatom Cyclotella cryptica under different growth conditions, finding that heterotrophic growth leads to higher EPA production, productivity, and potential for biotechnological exploitation.
Article
Fisheries
M. B. Betancor, A. MacEwan, M. Sprague, X. Gong, D. Montero, L. Han, J. A. Napier, F. Norambuena, M. Izquierdo, D. R. Tocher
Summary: The study showed that a genetically modified Camelina oil can replace fish oil without detrimental effects on the growth or feed efficiency of European seabass, while also improving the nutritional quality of the fish fillet.
Article
Nutrition & Dietetics
Lidia Ciccone, Susanna Nencetti, Armando Rossello, Lucia Barlettani, Nicolo Tonali, Paola Nieri, Elisabetta Orlandini
Summary: EPA and DHA, two omega-3 polyunsaturated fatty acids, are safe dietary supplements derived from fish oil that contribute to human health. Studies show that these fatty acids have a role in counteracting neurodegenerative processes related to amyloidogenic proteins. The research found that EPA and DHA can directly interact with TTR and contribute to stabilizing the TTR tetramer.
Article
Nutrition & Dietetics
Roberta Dourado Cavalcante da Cunha de Sa, Jussara de Jesus Simao, Viviane Simoes da Silva, Talita Mendes de Farias, Maysa Mariana Cruz, Vitor Jaco Antraco, Lucia Armelin-Correa, Maria Isabel Alonso-Vale
Summary: This study found that different ratios of EPA and DHA have different impacts on adipose tissue metabolism, with fish oil rich in EPA instead of DHA effectively reversing changes induced by obesity.
