Current and emerging concepts on the role of peripheral signals in the control of food intake and development of obesity

Food reward, hyperphagia, and obesity

(2011) Hans-Rudolf Berthoud et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Circulating GLP-1 and CCK-8 reduce food intake by capsaicin-insensitive, nonvagal mechanisms

(2011) Jingchuan Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Effects of carbohydrate sugars and artificial sweeteners on appetite and the secretion of gastrointestinal satiety peptides

(2011) Robert E. Steinert et al.   BRITISH JOURNAL OF NUTRITION

Up-regulation of intestinal type 1 taste receptor 3 and sodium glucose luminal transporter-1 expression and increased sucrose intake in mice lacking gut microbiota

(2011) T. D. Swartz et al.   BRITISH JOURNAL OF NUTRITION

Intracellular Signals Mediating the Food Intake-Suppressive Effects of Hindbrain Glucagon-like Peptide-1 Receptor Activation

(2011) Matthew R. Hayes et al.   Cell Metabolism

Diet and Gastrointestinal Bypass–Induced Weight Loss

(2011) Keval Chandarana et al.   DIABETES

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

(2011) Amandine Everard et al.   DIABETES

Peripheral and Central GLP-1 Receptor Populations Mediate the Anorectic Effects of Peripherally Administered GLP-1 Receptor Agonists, Liraglutide and Exendin-4

(2011) Scott E. Kanoski et al.   ENDOCRINOLOGY

Food reward functions as affected by obesity and bariatric surgery

(2011) A C Shin et al.   INTERNATIONAL JOURNAL OF OBESITY

Youth at Risk for Obesity Show Greater Activation of Striatal and Somatosensory Regions to Food

(2011) E. Stice et al.   JOURNAL OF NEUROSCIENCE

Reward Mechanisms in Obesity: New Insights and Future Directions

(2011) Paul J. Kenny   NEURON

Comparative Effects of the Long-Acting GLP-1 Receptor Ligands, Liraglutide and Exendin-4, on Food Intake and Body Weight Suppression in Rats

(2011) Matthew R. Hayes et al.   Obesity

The short term satiety peptide cholecystokinin reduces meal size and prolongs intermeal interval

(2011) Dalya M. Lateef et al.   PEPTIDES

Obesity surgery and gut–brain communication

(2011) Hans-Rudolf Berthoud et al.   PHYSIOLOGY & BEHAVIOR

Maintenance on a high-fat diet impairs the anorexic response to glucagon-like-peptide-1 receptor activation

(2011) Diana L. Williams et al.   PHYSIOLOGY & BEHAVIOR

Intestinal feedback signaling and satiety

(2011) Timothy H. Moran et al.   PHYSIOLOGY & BEHAVIOR

Oral fatty acid signaling and intestinal lipid processing: Support and supposition

(2011) Richard D. Mattes   PHYSIOLOGY & BEHAVIOR

Decreased expression of CD36 in circumvallate taste buds of high-fat diet induced obese rats

(2010) Xiao-Juan Zhang et al.   ACTA HISTOCHEMICA

Genetic variation in TAS1R2 (Ile191Val) is associated with consumption of sugars in overweight and obese individuals in 2 distinct populations

(2010) Karen M Eny et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation

(2010) Claire Barbier de La Serre et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Deficits in gastrointestinal responses controlling food intake and body weight

(2010) Mihai Covasa   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Oral sensitivity to fatty acids, food consumption and BMI in human subjects

(2010) Jessica E. Stewart et al.   BRITISH JOURNAL OF NUTRITION

T1R3 is expressed in brush cells and ghrelin-producing cells of murine stomach

(2010) Nicole Hass et al.   CELL AND TISSUE RESEARCH

Gut microbiota as a regulator of energy homeostasis and ectopic fat deposition: mechanisms and implications for metabolic disorders

(2010) Giovanni Musso et al.   CURRENT OPINION IN LIPIDOLOGY

PYY3-36 and Oxyntomodulin Can Be Additive in Their Effect on Food Intake in Overweight and Obese Humans

(2010) B. C. T. Field et al.   DIABETES

Meal-Induced Hormone Responses in a Rat Model of Roux-en-Y Gastric Bypass Surgery

(2010) Andrew C. Shin et al.   ENDOCRINOLOGY

Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism

(2010) Sylvie Rabot et al.   FASEB JOURNAL

The Hyperphagic Effect of Ghrelin Is Inhibited in Mice by a Diet High in Fat

(2010) James V. Gardiner et al.   GASTROENTEROLOGY

The G-Protein−Coupled Receptor GPR40 Directly Mediates Long-Chain Fatty Acid−Induced Secretion of Cholecystokinin

(2010) Alice P. Liou et al.   GASTROENTEROLOGY

Subcutaneous oxyntomodulin analogue administration reduces body weight in lean and obese rodents

(2010) Y-L Liu et al.   INTERNATIONAL JOURNAL OF OBESITY

Enhanced Hypothalamic Leptin Signaling in Mice Lacking Dopamine D2Receptors

(2010) Kyu Seok Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Taste Preference for Fatty Acids Is Mediated by GPR40 and GPR120

(2010) C. Cartoni et al.   JOURNAL OF NEUROSCIENCE

Weight Gain Is Associated with Reduced Striatal Response to Palatable Food

(2010) E. Stice et al.   JOURNAL OF NEUROSCIENCE

Reduced Sensitivity to Cholecystokinin in Male Rats Fed a High-Fat Diet Is Reversible

(2010) Timothy D. Swartz et al.   JOURNAL OF NUTRITION

Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARγ-related adipogenesis in the white adipose tissue of high-fat diet-fed mice

(2010) Evelyne M. Dewulf et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Changes in Gastrointestinal Hormones and Leptin after Roux-en-Y Gastric Bypass Procedure: A Review

(2010) Lauren M. Beckman et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

The endocannabinoid system links gut microbiota to adipogenesis

(2010) Giulio G Muccioli et al.   Molecular Systems Biology

Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

(2010) Paul M Johnson et al.   NATURE NEUROSCIENCE

Reward circuitry responsivity to food predicts future increases in body mass: Moderating effects of DRD2 and DRD4

(2010) Eric Stice et al.   NEUROIMAGE

Lack of Association of CD36 SNPs With Early Onset Obesity: A Meta-Analysis in 9,973 European Subjects

(2010) Hélène Choquet et al.   Obesity

Effects of Exendin-4 Alone and With Peptide YY3–36 on Food Intake and Body Weight in Diet-Induced Obese Rats

(2010) Roger D. Reidelberger et al.   Obesity

GLP-1 antagonism with exendin (9–39) fails to increase spontaneous meal size in rats

(2010) Elisabeth B. Rüttimann et al.   PHYSIOLOGY & BEHAVIOR

Multi-hormonal weight loss combinations in diet-induced obese rats: Therapeutic potential of cholecystokinin?

(2010) James L. Trevaskis et al.   PHYSIOLOGY & BEHAVIOR

Exenatide therapy in insulin-treated type 2 diabetes and obesity

(2010) U. A. Nayak et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Glucose and Weight Control in Mice with a Designed Ghrelin O-Acyltransferase Inhibitor

(2010) B. P. Barnett et al.   SCIENCE

Leptin increases striatal dopamine D2 receptor binding in leptin-deficient obese (ob/ob) mice

(2010) Jennifer Pfaffly et al.   SYNAPSE

Taste and weight: is there a link?

(2009) Lucy F Donaldson et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Is There a Fatty Acid Taste?

(2009) Richard D. Mattes   Annual Review of Nutrition

The Control of Food Intake: Behavioral versus Molecular Perspectives

(2009) Stephen C. Woods   Cell Metabolism

Interplay between obesity and associated metabolic disorders: new insights into the gut microbiota

(2009) Patrice D Cani et al.   CURRENT OPINION IN PHARMACOLOGY

The Role of the Gut Microbiota in Energy Metabolism and Metabolic Disease

(2009) Patrice Cani et al.   CURRENT PHARMACEUTICAL DESIGN

Leptin and the systems neuroscience of meal size control

(2009) Harvey J. Grill   FRONTIERS IN NEUROENDOCRINOLOGY

High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity

(2009) Marie A. Hildebrandt et al.   GASTROENTEROLOGY

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes

(2009) A Rodríguez et al.   INTERNATIONAL JOURNAL OF OBESITY

Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study

(2009) Arne Astrup et al.   LANCET

GOAT links dietary lipids with the endocrine control of energy balance

(2009) Henriette Kirchner et al.   NATURE MEDICINE

Combination of Bypassing Stomach and Vagus Dissection in High-Fat Diet-Induced Obese Rats—A Long-Term Investigation

(2009) Yong Wang et al.   OBESITY SURGERY

Gut hormones: Implications for the treatment of obesity

(2009) Marianne T. Neary et al.   PHARMACOLOGY & THERAPEUTICS

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Dose-dependent effects of cholecystokinin-8 on antropyloroduodenal motility, gastrointestinal hormones, appetite, and energy intake in healthy men

(2008) Ixchel M. Brennan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Possible entrainment of ghrelin to habitual meal patterns in humans

(2008) Julie M. Frecka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Loss of cholecystokinin and glucagon-like peptide-1-induced satiation in mice lacking serotonin 2C receptors

(2008) Lori Asarian   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

(2008) Jing Yang et al.   CELL

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Ghrelin Modulates Brain Activity in Areas that Control Appetitive Behavior

(2008) Saima Malik et al.   Cell Metabolism

Acute Effects of Glucagon-Like Peptide-1 on Hypothalamic Neuropeptide and AMP Activated Kinase Expression in Fasted Rats

(2008) Sanghee SEO et al.   ENDOCRINE JOURNAL

Amylin-Mediated Restoration of Leptin Responsiveness in Diet-Induced Obesity: Magnitude and Mechanisms

(2008) James L. Trevaskis et al.   ENDOCRINOLOGY

Intrameal Hepatic Portal and Intraperitoneal Infusions of Glucagon-Like Peptide-1 Reduce Spontaneous Meal Size in the Rat via Different Mechanisms

(2008) Elisabeth B. Rüttimann et al.   ENDOCRINOLOGY

Evidence that Intestinal Glucagon-Like Peptide-1 Plays a Physiological Role in Satiety

(2008) Diana L. Williams et al.   ENDOCRINOLOGY

Evidence for defective mesolimbic dopamine exocytosis in obesity-prone rats

(2008) Brenda M. Geiger et al.   FASEB JOURNAL

Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes

(2008) R L Young et al.   GUT

Hyperghrelinemia Precedes Obesity in Prader-Willi Syndrome

(2008) Eva Feigerlová et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic β cells

(2008) Toshiki Tanaka et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Cholecystokinin-58 is more potent in inhibiting food intake than cholecystokinin-8 in rats

(2008) Joerg Glatzle et al.   NUTRITIONAL NEUROSCIENCE

Developmental Changes of Gut Microflora and Enzyme Activity in Rat Pups Exposed to Fat-rich Diet

(2008) Štefan Mozeš et al.   Obesity

Central and Peripheral Regulation of Food Intake and Physical Activity: Pathways and Genes

(2008) Natalie R. Lenard et al.   Obesity

Differential leptin access into the brain — A hierarchical organization of hypothalamic leptin target sites?

(2008) Heike Münzberg   PHYSIOLOGY & BEHAVIOR

Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies

(2008) J. D. Roth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relation Between Obesity and Blunted Striatal Response to Food Is Moderated by TaqIA A1 Allele

(2008) E. Stice et al.   SCIENCE

Introducing GOAT: a target for obesity and anti-diabetic drugs?

(2008) Oreste Gualillo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES