Article
Nutrition & Dietetics
Yumeng Hua, Ziwei Zhang, Aiping Liu
Summary: This study evaluated the long-term diet quality of Chinese adults and explored its role in diabetes prevention. The results showed a significant positive association between diet quality scores and diabetes risks, suggesting the importance of healthy diets in preventing diabetes in Asia.
Review
Nutrition & Dietetics
Paula Brauer, Dawna Royall, Ariellia Rodrigues
Summary: This study systematically reviewed intervention studies using the Healthy Eating Index (HEI) and its adaptations to examine whether diet interventions improve diet quality. Results showed that diet quality improved, especially in studies focusing on multiple food behaviors and comparing intensive, long-term interventions with no-treatment control groups.
ADVANCES IN NUTRITION
(2021)
Article
Virology
Victoria Panagiota, Christiane Dobbelstein, Sonja Werwitzke, Arnold Ganser, Nina Cooper, Ulrich J. Sachs, Andreas Tiede
Summary: VITT is a rare but serious complication of adenovirus-based vaccines. Eculizumab may be considered as a rescue agent. Long-term management with direct oral anticoagulants appears to be safe and effective.
Article
Biochemistry & Molecular Biology
Megumi Ueno, Shuang Liu, Takeshi Kiyoi, Masaki Mogi, Takashi Sugiyama
Summary: This study investigated the long-term effects of maternal balanced low-fat interventions on the offspring's metabolic homeostasis. The results showed that changes in maternal dietary composition improved glucose metabolism and insulin levels in the offspring, and compensated for the detrimental effects of a high-fat diet by changing the gene expression profile.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2022)
Article
Food Science & Technology
Ines Dominguez-Lopez, Maria Marhuenda-Munoz, Anna Tresserra-Rimbau, Alvaro Hernaez, Juan Jose Moreno, Miguel Angel Martinez-Gonzalez, Jordi Salas-Salvado, Dolores Corella, Montserrat Fito, Jose Alfredo Martinez, Angel M. Alonso-Gomez, Julia Warnberg, Jesus Vioque, Dora Romaguera, Jose Lopez-Miranda, M. Rosa Bernal-Lopez, Jose Lapetra, J. Luis Serra-Majem, Aurora Bueno-Cavanillas, Josep A. Tur, Vicente Martin-Sanchez, Xavier Pinto, Miguel Delgado-Rodriguez, Pilar Matia-Martin, Josep Vidal, Clotilde Vazquez, Lidia Daimiel, Merce Serra-Mir, Zenaida Vazquez-Ruiz, Stephanie K. Nishi, Jose Sorli, Olga Castaner, Itziar Abete, Jessica Vaquero Luna, Rosa Carabano-Moral, Alberto Asencio, Lara Prohens, Antonio Garcia-Rios, Rosa Casas, Ana Maria Gomez-Perez, Jose Manuel Santos-Lozano, Cristina Razquin, Maria Angeles Martinez, Carmen Saiz, Vanesa Robledo-Pastor, Maria Angeles Zulet, Itziar Salaverria, Sonia Eguaras, Nancy Babio, Mireia Malcampo, Emilio Ros, Ramon Estruch, M. Carmen Lopez-Sabater, Rosa M. Lamuela-Raventos
Summary: The study aimed to assess the relationship between fruit and vegetable consumption and plasma fatty acids, showing that high fruit and vegetable consumption is associated with lower plasma saturated fatty acids.
MOLECULAR NUTRITION & FOOD RESEARCH
(2021)
Article
Medicine, General & Internal
Javier Delgado-Lista, Juan F. Alcala-Diaz, Jose Torres-Pena, Gracia M. Quintana-Navarro, Francisco Fuentes, Antonio Garcia-Rios, Ana M. Ortiz-Morales, Ana Gonzalez-Requero, Ana Perez-Caballero, Elena M. Yubero-Serrano, Oriol A. Rangel-Zuniga, Antonio Camargo, Fernando Rodriguez-Cantalejo, Fernando Lopez-Segura, Lina Badimon, Jose M. Ordovas, Francisco Perez-Jimenez, Pablo Perez-Martinez, Jose Lopez-Miranda
Summary: The study compared the effects of Mediterranean diet and low-fat diet in the secondary prevention of cardiovascular disease, showing that the Mediterranean diet was superior in preventing major cardiovascular events.
Article
Food Science & Technology
Takuo Nakazeko, Naohisa Shobako, Yukio Hirano, Futoshi Nakamura, Keiko Honda
Summary: This study developed a novel dietary intervention using nutritionally balanced meals and conducted trials in two companies. The results showed that consuming these meals significantly improved the scores of the Work Limitation Questionnaire, as well as body weight, Body Mass Index, waist circumference, visceral fat, and increased the number of defecations.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Hematology
Andrew J. Doyle, Matthew J. Stubbs, Tina Dutt, Will Lester, Will Thomas, Joost van Veen, Joannes Hermans, Tanya Cranfield, Quentin A. Hill, Amanda Clark, Catherine Bagot, Steven Austin, John -Paul Westwood, Mari Thomas, Marie Scully
Summary: Relapse is a risk for patients with immune-mediated thrombotic thrombocytopenic purpura (iTTP) after acute treatment, but the identification of patients at risk and relapse patterns is not well established. This study in the UK followed iTTP patients for over 3 years to identify characteristics for relapse, assess relapse rates and patterns, and evaluate response to anti-CD20 therapy for ADAMTS13 relapses. Results showed a relapse rate of 40% after 5 years, with no difference observed at 10-year follow-up. Black Caribbean ethnicity increased the risk of relapse. Early relapses occurred in 6% of patients, with subsequent relapses within 2 years. ADAMTS13 relapses accounted for nearly 60% of all relapses, and treatment reduced the risk of progression to clinical relapses. Regular monitoring and preemptive rituximab led to lower rates of clinical relapses in later diagnosed iTTP cases. Anti-CD20 therapy was effective for ADAMTS13 relapses and maintained treatment response after subsequent episodes.
Article
Immunology
Albrecht Guenther, Dirk Braemer, Mathias W. Pletz, Thomas Kamradt, Sabine Baumgart, Thomas E. Mayer, Michael Baier, Angelina Autsch, Christian Mawrin, Linda Schoenborn, Andreas Greinacher, Thomas Thiele
Summary: This study reported a VITT patient with an extremely severe condition, showing high titers of PF4-IgG antibodies, and described the treatment process and outcomes. Plasma exchange, immunoadsorption, and/or immunosuppressive treatment may be considered in such cases to reduce the high levels of anti-PF4-IgG.
Article
Nutrition & Dietetics
Hanan Abbas, Simone Perna, Afzal Shah, Clara Gasparri, Mariangela Rondanelli
Summary: This study evaluated the efficacy and safety of a hypocaloric diet under hospitalization in obese patients. The results showed that the diet led to weight reduction and improvements in blood biochemistry parameters, while not affecting muscle mass, liver, and thyroid profiles. Lower insulin levels and higher serum calcium and potassium levels were predictors of weight loss.
Article
Environmental Sciences
Chloe S. Kim, Stephanie T. Grady, Jaime E. Hart, Francine Laden, Trang VoPham, Daniel D. Nguyen, JoAnn E. Manson, Peter James, John P. Forman, Kathryn M. Rexrode, Jonathan Levy, Junenette L. Peters
Summary: This study used high spatial resolution aircraft noise exposure estimates over a 20-year period to examine the association between aircraft noise and incident hypertension in two cohorts of female nurses. The study found limited evidence of a positive association between aircraft noise exposure and hypertension.
ENVIRONMENTAL RESEARCH
(2022)
Review
Physiology
Cintia Romina Gatti, Dalmiro Gomez Ribot, Javier Mariani, Alicia Jawerbaum
Summary: The study suggests that increased dietary intake of MUFAs during the periconception period may have a positive effect on achieving pregnancy, while increased intake of PUFAs does not show significant effects.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Medicine, General & Internal
Sruthi Selvakumar, Angela Liu, Shruti Chaturvedi
Summary: Advances in diagnosis and treatment have significantly improved survival rates of acute immune thrombotic thrombocytopenic purpura (iTTP) and changed it from an acute fatal condition to a chronic relapsing disorder. iTTP survivors are at risk of various adverse outcomes, including higher rates of all-cause mortality, cardiovascular diseases, and comorbidities like obesity and autoimmune disorders. Women with iTTP face risks of recurrence, preeclampsia, and other complications during subsequent pregnancies. ADAMTS13 activity during remission is an important factor for predicting relapse and other outcomes. This review summarizes the epidemiology and mechanisms of adverse long-term sequelae of iTTP, current best practices in survivorship care, and research agenda for improving long-term outcomes.
FRONTIERS IN MEDICINE
(2023)
Article
Nutrition & Dietetics
Alessandro Virtuoso, Pernille Tveden-Nyborg, Anne Marie Voigt Schou-Pedersen, Jens Lykkesfeldt, Heidi Kaastrup Mueller, Betina Elfving, Dorte Bratbo Sorensen
Summary: The effect of high-fat feeding on brain-derived neurotrophic factor (BDNF) is conflicting. This study found that chronic, restricted access to Cafeteria Diets (CAF) increased BDNF levels in the prefrontal cortex (PFC) of rats, suggesting that this may be a suboptimal feeding regime.
Article
Medicine, General & Internal
Stacy A. Clemes, Veronica Varela-Mato, Danielle H. Bodicoat, Cassandra L. Brookes, Yu-Ling Chen, Charlotte L. Edwardson, Laura J. Gray, Amber J. Guest, Vicki Johnson, Fehmidah Munir, Nicola J. Paine, Gerry Richardson, Katharina Ruettger, Mohsen Sayyah, Aron Sherry, Ana Suazo Di Paola, Jacqui Troughton, Thomas Yates, James A. King
Summary: The study evaluated the effectiveness of the 'Structured Health Intervention For Truckers' (SHIFT) program on long-distance heavy goods vehicle drivers. It found that at the 6-month follow-up, drivers who participated in the program experienced significantly higher daily step counts, reduced sitting time, and increased moderate-to-vigorous physical activity. However, these differences were not maintained at the 16-18-month follow-up. The program shows potential in promoting physical activity among this underserved occupational group.
Article
Nutrition & Dietetics
Line E. Landgrebe, Vibeke Andersen, Corinna Bang, Lucas Moitinho-Silva, Herbert Schwarz, Claus B. Juhl, Else-Marie Bladbjerg
Summary: Repeated weight loss cycles may lead to increased cardiovascular morbidity. Meal-induced thrombin formation, observed in individuals with overweight after weight loss, may be one of the mechanisms underlying harm during intentional weight loss. Consumption of high-fat meals during intentional weight loss may trigger a prothrombotic state by increasing postprandial F1 + 2 or decreasing fibrin clot lysis, and this response may be associated with gut bacteria composition.
NUTRITION RESEARCH
(2022)
Article
Pediatrics
Michelle D. Pang, Hulya Yilmaz, Arne Astrup, Ellen E. Blaak, Marleen A. Baak
Summary: This study found a positive association between changes in body mass index of parents and their children during a weight-maintenance family-based dietary intervention. Including parents in family-based dietary approaches for weight management of their children is effective, regardless of the child's weight status.
Article
Respiratory System
Ayse Dudu Altintas Dogan, Ole Hilberg, SOren Hess, Torben Tranborg Jensen, Else-Marie Bladbjerg, Claus Bogh Juhl
Summary: This study investigated the effect of liraglutide on pulmonary function in individuals with obesity and COPD. The results showed that liraglutide use led to weight loss, improved pulmonary function, and reduced clinical impact of COPD.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2022)
Article
Nutrition & Dietetics
Nicole Jacqueline Jensen, Helena Zander Wodschow, Mads Juul Skytte, Amirsalar Samkani, Arne Astrup, Jan Frystyk, Bolette Hartmann, Jens Juul Holst, Thomas Meinert Larsen, Sten Madsbad, Faidon Magkos, Kamilla Woznica Miskowiak, Steen Bendix Haugaard, Thure Krarup, Jorgen Rungby, Mads Norvin Thomsen
Summary: The study evaluated the effects of dietary carbohydrate restriction on health-related quality of life (HRQoL) and cognition in individuals with type 2 diabetes. The results showed that weight loss improved physical health, while the amount of carbohydrates, protein, and fat in the diet may affect mental health and cognition.
CLINICAL NUTRITION
(2022)
Article
Rehabilitation
Anette Due, Anne Marie Beck, Camilla Banke Birk, Lise Justesen, Maj Majgaard, Mette Lei, Sara Koldkaer S. Langsted, Tilde Skjaerlund Jensen
Summary: This study aimed to test the feasibility of different meal service programs for old people living at home. An 8-week trial was conducted, comparing three different programs with standard care. The results showed that the programs were feasible and provided several benefits for completers.
CLINICAL REHABILITATION
(2022)
Letter
Endocrinology & Metabolism
Mads N. Thomsen, Arne Astrup, Jens J. Holst, Sten Madsbad, Faidon Magkos, Steen B. Haugaard, Thure Krarup
Article
Endocrinology & Metabolism
Kim Huynh, Marianne Klose, Kim Krogsgaard, Jorgen Drejer, Sarah Byberg, Sten Madsbad, Faidon Magkos, Abdellatif Aharaz, Berit Edsberg, Jacob Tfelt-Hansen, Arne Vernon Astrup, Ulla Feldt-Rasmussen
Summary: This study investigated the safety and efficacy of Tesomet in adults with hypothalamic obesity. The results showed that Tesomet significantly reduced body weight compared to placebo and was well-tolerated.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2022)
Article
Nutrition & Dietetics
A. Asirup, C. A. Monteiro
Summary: The Nova classification of UPFs is based on poorly defined processes and presence of additives, leading to misclassification. High palatability of UPFs is said to promote overconsumption and obesity, but evidence supporting this beyond nutrient composition is lacking. Observational studies link UPF intake with obesity, but no independent associations have been found after accounting for confounders. A highly cited feeding study showed that reduced energy intake from UPFs can be explained by other dietary factors. Considering existing nutrient profiling systems already capture key determinants of chronic disease risk, the Nova classification adds little value.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Carlos A. Monteiro, Arne Astrup
Summary: The recommendation to choose unprocessed or minimally processed foods and freshly made meals over ultra-processed foods is gaining traction in official dietary guidelines. This recommendation is backed by research showing that a higher intake of ultra-processed foods is linked to poor-quality diets and increased risks of chronic diseases.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Letter
Nutrition & Dietetics
Nicole Jacqueline Jensen, Mads Norvin Thomsen, Mads Juul Skytte, Arne Astrup, Jens Juul Holst, Sten Madsbad, Faidon Magkos, Kamilla Woznica Miskowiak, Steen Bendix Haugaard, Thure Krarup, Jorgen Rungby
CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
David S. Ludwig, Caroline M. Apovian, Louis J. Aronne, Arne Astrup, Lewis C. Cantley, Cara B. Ebbeling, Steven B. Heymsfield, James D. Johnson, Janet C. King, Ronald M. Krauss, Gary Taubes, Jeff S. Volek, Eric C. Westman, Walter C. Willett, William S. Yancy, Mark Friedman
Summary: The obesity pandemic continues to spread despite efforts to decrease energy intake and increase energy expenditure. There are two possible explanations for this failure: the public has not fully embraced the current approach, or the approach itself is based on an erroneous paradigm. The energy balance model attributes obesity to overeating, while the carbohydrate-insulin model suggests that hormonal responses to processed carbohydrates lead to energy deposition in adipose tissue. Resolving the deficiencies in the energy balance model is crucial to inform prevention and treatment strategies, but both models agree on targeting processed carbohydrates as major drivers of obesity.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Nikita Misella Hansen, Peder Berg, Marianne Rix, Manan Pareek, Jens Leipziger, Anne -Lise Kamper, Arne Astrup, Mads Vaarby Sorensen, Louise Salomo
Summary: The objective of this study was to evaluate the effects of the New Nordic Renal Diet (NNRD) on metabolic acidosis and uremic toxins in patients with moderate CKD. The results showed that one week of NNRD effectively improved metabolic acidosis and reduced urinary excretion of uric acid and uremic toxins. These results provide encouragement for further investigations on the long-term renal protection effects of NNRD in patients with CKD.
JOURNAL OF RENAL NUTRITION
(2023)
Article
Medicine, General & Internal
Sebastien Bailly, Odile Fabre, Mallory Cals-Maurette, Laurent Pantagis, Robin Terrail, Remy Legrand, Arne Astrup, Jean-Louis Pepin
Summary: This study assessed the impact of a weight-loss program on OSA risk and daytime sleepiness. The results showed that the program led to significant weight loss and improvement in both OSA and subjective daytime sleepiness.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Endocrinology & Metabolism
Mette Bogehave, Dorte Glintborg, Jorgen Brodersen Gram, Else-Marie Bladbjerg, Marianne Skovsager Andersen, Johannes Jakobsen Sidelmann
Summary: Hypogonadism is common during opioid treatment and is associated with cardiovascular disease. The effects of testosterone replacement therapy (TRT) on the coagulation system in opioid-treated men were investigated. TRT was found to have an anticoagulant effect by suppressing the tissue factor pathway in men with opioid-induced hypogonadism.
ENDOCRINE CONNECTIONS
(2023)
Article
Multidisciplinary Sciences
Cheryl Achterberg, Arne Astrup, Dennis M. Bier, Janet C. King, Ronald M. Krauss, Nina Teicholz, Jeff S. Volek
Summary: This paper discusses the issues with the US Dietary Guidelines for Americans over the past 40 years, including the insufficient assessment of scientific evidence and lack of transparency in the guideline development process. The paper highlights that the current guidelines have not fully adhered to the relevant laws and regulations, resulting in a lack of independence for the expert committee evaluating the science and a continued absence of a fully rigorous scientific process.