Time dependent analysis of assay comparability: a novel approach to understand intra- and inter-site variability over time

How Experimental Errors Influence Drug Metabolism and Pharmacokinetic QSAR/QSPR Models

(2014) Mark C. Wenlock et al.   Journal of Chemical Information and Modeling

QSAR with experimental and predictive distributions: an information theoretic approach for assessing model quality

(2013) David J. Wood et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

The right compound in the right assay at the right time: an integrated discovery DMPK strategy

(2012) Peter Ballard et al.   DRUG METABOLISM REVIEWS

Strategies for the generation, validation and application ofin silicoADMET models in lead generation and optimization

(2012) Matthew Paul Gleeson et al.   Expert Opinion on Drug Metabolism & Toxicology

Practical use of the regression offset approach for the prediction ofin vivointrinsic clearance from hepatocytes

(2012) Anna-Karin Sohlenius-Sternbeck et al.   XENOBIOTICA

Hypothesis driven drug design: improving quality and effectiveness of the design-make-test-analyse cycle

(2011) Alleyn T. Plowright et al.   DRUG DISCOVERY TODAY

High-throughput metabolic stability studies in drug discovery by orthogonal acceleration time-of-flight (OATOF) with analogue-to-digital signal capture (ADC)

(2010) David G. Temesi et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

The analysis of very small samples of repeated measurements I: An adjusted sandwich estimator

(2010) Simon S. Skene et al.   STATISTICS IN MEDICINE

Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds

(2010) A.-K. Sohlenius-Sternbeck et al.   XENOBIOTICA

High Throughput Screening of Physicochemical Properties and In Vitro ADME Profiling in Drug Discovery

(2009) Hong Wan et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Statistical Models for Assessing Agreement in Method Comparison Studies with Replicate Measurements

(2008) Bendix Carstensen et al.  

Design and Analysis of Analytical Method Transfer Studies

(2008) James R. Schwenke et al.   Journal of Biopharmaceutical Statistics

Validation of a Rapid Equilibrium Dialysis Approach for the Measurement of Plasma Protein Binding

(2008) Nigel J. Waters et al.   JOURNAL OF PHARMACEUTICAL SCIENCES