Red blood cells of sickle cell disease patients exhibit abnormally high abundance of N-methyl D-aspartate receptors mediating excessive calcium uptake

Gene Therapy for Hemoglobinopathies

(2014) Shanmuganathan Chandrakasan et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

N-methyl-d-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the intracellular calcium regulation

(2013) Asya Makhro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease

(2013) A. George et al.   BLOOD

Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies

(2013) D. Manwani et al.   BLOOD

Outcome of patients with hemoglobinopathies given either cord blood or bone marrow transplantation from an HLA-identical sibling

(2013) F. Locatelli et al.   BLOOD

Memantine, a promising drug for the prevention of neuropathic pain in rat

(2013) Véronique Morel et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Calcium in Red Blood Cells—A Perilous Balance

(2013) Anna Bogdanova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

Biologic Complexity in Sickle Cell Disease: Implications for Developing Targeted Therapeutics

(2013) Beatrice E. Gee   TheScientificWorldJOURNAL

Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease

(2012) Lucia De Franceschi et al.   FASEB JOURNAL

N-Methyl-d-aspartate Receptor Mechanosensitivity Is Governed by C Terminus of NR2B Subunit

(2011) Pallab Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional NMDA receptors in rat erythrocytes

(2010) Asya Makhro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hypoxia Activates a Ca2+-Permeable Cation Conductance Sensitive to Carbon Monoxide and to GsMTx-4 in Human and Mouse Sickle Erythrocytes

(2010) David H. Vandorpe et al.   PLoS One

Band 3 catalyzes sickle hemoglobin polymerization

(2009) Maria A. Rotter et al.   BIOPHYSICAL CHEMISTRY

Senicapoc (ICA-17043): a potential therapy for the prevention and treatment of hemolysis-associated complications in sickle cell anemia

(2009) Kenneth I Ataga et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS