Storage and secretion of naturally occurring von Willebrand factor A domain variants

How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: The early history of ERAD

(2013) Patrick G. Needham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease

(2013) J. Eikenboom et al.   BLOOD

Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease

(2013) J.-W. Wang et al.   BLOOD

Cellular and molecular basis of von Willebrand disease: studies on blood outgrowth endothelial cells

(2013) R. D. Starke et al.   BLOOD

Reduced von Willebrand factor secretion is associated with loss of Weibel-Palade body formation

(2012) G. CASTAMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Establishment of outgrowth endothelial cells from peripheral blood

(2012) Javier Martin-Ramirez et al.   Nature Protocols

Functional architecture of Weibel-Palade bodies

(2011) K. M. Valentijn et al.   BLOOD

Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies

(2011) E. A. M. Bouwens et al.   BLOOD

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models

(2011) C. M. Pruss et al.   BLOOD

Biogenesis of Weibel-Palade bodies in von Willebrand's disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation

(2011) J.-W. Wang et al.   HAEMATOLOGICA

Intracellular Storage and Regulated Secretion of Von Willebrand Factor in Quantitative Von Willebrand Disease

(2011) Jiong-Wei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium modulates force sensing by the von Willebrand factor A2 domain

(2011) Arjen J. Jakobi et al.   Nature Communications

Multigranular exocytosis of Weibel-Palade bodies in vascular endothelial cells

(2010) K. M. Valentijn et al.   BLOOD

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells

(2009) M. van den Biggelaar et al.   HAEMATOLOGICA

Expression of 14 von Willebrand factor mutations identified in patients with type 1 von Willebrand disease from the MCMDM-1VWD study

(2009) J. EIKENBOOM et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Response to desmopressin is influenced by the genotype and phenotype in type 1 von Willebrand disease (VWD): results from the European Study MCMDM-1VWD

(2008) G. Castaman et al.   BLOOD

Detailed von Willebrand factor multimer analysis in patients with von Willebrand disease in the European study, molecular and clinical markers for the diagnosis and management of type 1 von Willebrand disease (MCMDM-1VWD)

(2008) U. BUDDE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Assembly of Weibel Palade body-like tubules from N-terminal domains of von Willebrand factor

(2008) R.-H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new look at Weibel–Palade body structure in endothelial cells using electron tomography

(2007) K.M. Valentijn et al.   JOURNAL OF STRUCTURAL BIOLOGY