Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies

C1 domain residues Lys 2092 and Phe 2093 are of major importance for the endocytic uptake of coagulation factor VIII

(2011) Henriët Meems et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Activation of human endothelial cells from specific vascular beds induces the release of a FVIII storage pool

(2010) T. Shahani et al.   BLOOD

Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A

(2010) Q. Shi et al.   BLOOD

Multigranular exocytosis of Weibel-Palade bodies in vascular endothelial cells

(2010) K. M. Valentijn et al.   BLOOD

TMEPAI, a Transmembrane TGF-β-Inducible Protein, Sequesters Smad Proteins from Active Participation in TGF-β Signaling

(2010) Yukihide Watanabe et al.   MOLECULAR CELL

Endothelial Cell Processing and Alternatively Spliced Transcripts of Factor VIII: Potential Implications for Coagulation Cascades and Pulmonary Hypertension

(2010) Claire L. Shovlin et al.   PLoS One

An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF

(2009) W. Pos et al.   BLOOD

Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells

(2009) M. van den Biggelaar et al.   HAEMATOLOGICA

von Willebrand factor assembly and secretion

(2009) J. E. SADLER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Structural organization of Weibel-Palade bodies revealed by cryo-EM of vitrified endothelial cells

(2009) J. A. Berriman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles

(2008) M. van den Biggelaar et al.   BLOOD

Covalent regulation of ULVWF string formation and elongation on endothelial cells under flow conditions

(2008) Y. LI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13

(2008) W. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembly of Weibel Palade body-like tubules from N-terminal domains of von Willebrand factor

(2008) R.-H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new look at Weibel–Palade body structure in endothelial cells using electron tomography

(2007) K.M. Valentijn et al.   JOURNAL OF STRUCTURAL BIOLOGY