Secrets of platelet exocytosis - what do we really know about platelet secretion mechanisms?

Dynamin-Related Protein-1 Controls Fusion Pore Dynamics During Platelet Granule Exocytosis

(2013) Secil Koseoglu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

I B kinase phosphorylation of SNAP-23 controls platelet secretion

(2013) Z. A. Karim et al.   BLOOD

Comment on “Platelet-Derived Nucleotides Promote Tumor Cell Transendothelial Migration and Metastasis via P2Y2 Receptor” by Schumacher et al.

(2013) Matthew T. Harper et al.   CANCER CELL

Platelet-Derived Nucleotides Promote Tumor-Cell Transendothelial Migration and Metastasis via P2Y2 Receptor

(2013) Dagmar Schumacher et al.   CANCER CELL

Munc13-4 is critical for thrombosis through regulating release of ADP from platelets

(2013) J. S. Savage et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Phosphorylation of CalDAG-GEFI by protein kinase A prevents Rap1b activation

(2013) H. Subramanian et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

(2013) Brett H. Herzog et al.   NATURE

Absence of Platelet Phenotype in Mice Lacking the Motor Protein Myosin Va

(2013) Matthew T. Harper et al.   PLoS One

Platelets Promote Tumor Growth and Metastasis via Direct Interaction between Aggrus/Podoplanin and CLEC-2

(2013) Satoshi Takagi et al.   PLoS One

Different Munc13 Isoforms Function as Priming Factors in Lytic Granule Release from Murine Cytotoxic T Lymphocytes

(2013) Monika Dudenhöffer-Pfeifer et al.   TRAFFIC

Platelet function and thymosin β4

(2012) Harmanpreet Kaur et al.   BIOLOGICAL CHEMISTRY

Mechanism of platelet dense granule biogenesis: study of cargo transport and function of Rab32 and Rab38 in a model system

(2012) A. L. Ambrosio et al.   BLOOD

Munc18b/STXBP2 is required for platelet secretion

(2012) R. Al Hawas et al.   BLOOD

Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion

(2012) S. Ye et al.   BLOOD

Granule exocytosis is required for platelet spreading: differential sorting of  -granules expressing VAMP-7

(2012) C. G. Peters et al.   BLOOD

Platelet secretion is kinetically heterogeneous in an agonist-responsive manner

(2012) D. Jonnalagadda et al.   BLOOD

Molecular determinants of platelet delta storage pool deficiencies: an update

(2012) Julien Masliah-Planchon et al.   BRITISH JOURNAL OF HAEMATOLOGY

Novel STXBP2 Mutation Causing Familial Hemophagocytic Lymphohistiocytosis

(2012) Rakhi Jain et al.   INDIAN PEDIATRICS

Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion

(2012) Kristin L. Boswell et al.   JOURNAL OF CELL BIOLOGY

All three components of the neuronal SNARE complex contribute to secretory vesicle docking

(2012) Yao Wu et al.   JOURNAL OF CELL BIOLOGY

Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets

(2012) A. HAMPSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Rho GTPases in platelet function

(2012) J. E. ASLAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Distinct Initial SNARE Configurations Underlying the Diversity of Exocytosis

(2012) Haruo Kasai et al.   PHYSIOLOGICAL REVIEWS

SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open

(2012) L. Shi et al.   SCIENCE

Platelet CLEC-2 and podoplanin in cancer metastasis

(2012) Kate L. Lowe et al.   THROMBOSIS RESEARCH

Exorcising the Exocyst Complex

(2012) Margaret R. Heider et al.   TRAFFIC

Rap1-Rac1 Circuits Potentiate Platelet Activation

(2011) Lucia Stefanini et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Quantitative immunofluorescence mapping reveals little functional coclustering of proteins within platelet  -granules

(2011) J. Kamykowski et al.   BLOOD

Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2

(2011) O. Konopatskaya et al.   BLOOD

Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis

(2011) I. Pleines et al.   BLOOD

Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes

(2011) J. W. Rowley et al.   BLOOD

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Distinct Roles for Rap1b Protein in Platelet Secretion and Integrin αIIbβ3Outside-in Signaling

(2011) Guoying Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelet-derived serotonin links vascular disease and tissue fibrosis

(2011) Clara Dees et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Advances in our understanding of the molecular basis of disorders of platelet function

(2011) A. NURDEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Historical perspective and future directions in platelet research

(2011) B. S. COLLER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Novel roles of cAMP/cGMP-dependent signaling in platelets

(2011) A. SMOLENSKI   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2

(2011) A. M. KERRIGAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Role of Rab GTPases in Membrane Traffic and Cell Physiology

(2011) Alex H. Hutagalung et al.   PHYSIOLOGICAL REVIEWS

Deletion of SNAP-23 Results in Pre-Implantation Embryonic Lethality in Mice

(2011) Young Ho Suh et al.   PLoS One

Platelets in atherosclerosis

(2011) Philipp von Hundelshausen et al.   THROMBOSIS AND HAEMOSTASIS

The Platelet Actin Cytoskeleton Associates with SNAREs and Participates in α-Granule Secretion

(2010) Kamil Woronowicz et al.   BIOCHEMISTRY

Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis

(2010) Q. Ren et al.   BLOOD

Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets

(2010) I. Pleines et al.   BLOOD

The platelet interior revisited: electron tomography reveals tubular  -granule subtypes

(2010) H. van Nispen tot Pannerden et al.   BLOOD

Cytoskeletal mechanics of proplatelet maturation and platelet release

(2010) Jonathan N. Thon et al.   JOURNAL OF CELL BIOLOGY

Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL-5) Is Caused by Mutations in Munc18-2 and Impaired Binding to Syntaxin 11

(2009) Udo zur Stadt et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Protein Kinase Cδ Differentially Regulates Platelet Functional Responses

(2009) Ramya Chari et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impaired activation of platelets lacking protein kinase C-  isoform

(2009) B. Nagy et al.   BLOOD

PKC  in platelet activation

(2009) M. T. Harper et al.   BLOOD

Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets

(2009) O. Neumuller et al.   BLOOD

Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo

(2009) G. J. Graham et al.   BLOOD

Platelet α-granules: Basic biology and clinical correlates

(2009) Price Blair et al.   BLOOD REVIEWS

Munc18/Syntaxin Interaction Kinetics Control Secretory Vesicle Dynamics

(2009) Colin Rickman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation

(2009) M. T. HARPER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet functions beyond hemostasis

(2009) S. S. SMYTH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA

(2009) A. A. KONDKAR et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The platelet release reaction: just when you thought platelet secretion was simple

(2008) Qiansheng Ren et al.   CURRENT OPINION IN HEMATOLOGY

Critical roles for the actin cytoskeleton and cdc42 in regulating platelet integrinα2β1

(2008) Giordano Pula et al.   PLATELETS