Bimodal immune activation in psoriasis

T-helper-1-cell cytokines drive cancer into senescence

(2013) Heidi Braumüller et al.   NATURE

Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1

(2012) Olaf Groß et al.   IMMUNITY

Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis

(2012) Kim A. Papp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

(2012) Craig Leonardi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutations in IL36RN/IL1F5 Are Associated with the Severe Episodic Inflammatory Skin Disease Known as Generalized Pustular Psoriasis

(2011) Alexandros Onoufriadis et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

(2011) Kamran Ghoreschi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression

(2011) Wolfram Hoetzenecker et al.   NATURE MEDICINE

Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis

(2011) Slaheddine Marrakchi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autoinflammatory Diseases: Clinical and Genetic Advances

(2010) S. Farasat et al.   ARCHIVES OF DERMATOLOGY

Autoinflammatory Disease Reloaded: A Clinical Perspective

(2010) Daniel L. Kastner et al.   CELL

Interleukin 4 or Cytokine Antagonists? Time to Change the Search for Novel Psoriasis Therapies

(2010) Martin Röcken   DERMATOLOGY

Nailing down the Genetic and Immunological Basis for Psoriatic Disease

(2010) Dennis McGonagle et al.   DERMATOLOGY

Cutting Edge: A Critical Functional Role for IL-23 in Psoriasis

(2010) G. Tonel et al.   JOURNAL OF IMMUNOLOGY

Inflammasomes and autoimmunity

(2010) Patrick J. Shaw et al.   TRENDS IN MOLECULAR MEDICINE

Direct crosstalk between mast cell-TNF and TNFR1-expressing endothelia mediates local tissue inflammation

(2009) M. Kneilling et al.   BLOOD

Autoinflammation: The prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses

(2009) Raphaela Goldbach-Mansky et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Developments in the scientific and clinical understanding of autoinflammatory disorders

(2009) Helen J Lachmann et al.   ARTHRITIS RESEARCH & THERAPY

The spectrum of monogenic autoinflammatory syndromes: Understanding disease mechanisms and use of targeted therapies

(2008) Rachel L. Glaser et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment

(2008) Cristina Albanesi et al.   JOURNAL OF EXPERIMENTAL MEDICINE