Use of magnetic resonance imaging in pharmacogenomics

Decreased hippocampal volume and increased anxiety in a transgenic mouse model expressing the human CYP2C19 gene

(2013) A Persson et al.   MOLECULAR PSYCHIATRY

Interaction of antidepressant and antipsychotic drugs with the human organic cation transporters hOCT1, hOCT2 and hOCT3

(2013) Britta Haenisch et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Mapping the hemodynamic response in human subjects to a dopaminergic challenge with dextroamphetamine using ASL-based pharmacological MRI

(2013) M.L.J. Schouw et al.   NEUROIMAGE

Effects of amisulpride on human resting cerebral perfusion

(2013) Roberto Viviani et al.   PSYCHOPHARMACOLOGY

Effective connectivity of AKT1-mediated dopaminergic working memory networks and pharmacogenetics of anti-dopaminergic treatment

(2012) Hao Yang Tan et al.   BRAIN

Acute effects of single-dose aripiprazole and haloperidol on resting cerebral blood flow (rCBF) in the human brain

(2012) Rowena Handley et al.   HUMAN BRAIN MAPPING

Genetic variability of drug-metabolizing enzymes: the dual impact on psychiatric therapy and regulation of brain function

(2012) J C Stingl et al.   MOLECULAR PSYCHIATRY

Effect of paroxetine and bupropion on human resting brain perfusion: An arterial spin labeling study

(2012) Roberto Viviani et al.   NEUROIMAGE

Pharmacologic magnetic resonance imaging (phMRI): Imaging drug action in the brain

(2012) Bruce G. Jenkins   NEUROIMAGE

Cortical responses to amphetamine exposure studied by pCASL MRI and pharmacokinetic/pharmacodynamic dose modeling

(2012) Love Engström Nordin et al.   NEUROIMAGE

Non-invasive imaging in experimental medicine for drug development

(2011) Paul M Matthews et al.   CURRENT OPINION IN PHARMACOLOGY

Potentials and Challenges for Arterial Spin Labeling in Pharmacological Magnetic Resonance Imaging

(2011) D. J. J. Wang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Epistatic interactions of AKT1 on human medial temporal lobe biology and pharmacogenetic implications

(2011) H Y Tan et al.   MOLECULAR PSYCHIATRY

Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response

(2011) A Bacq et al.   MOLECULAR PSYCHIATRY

Antidepressant medications reduce subcortical–cortical resting-state functional connectivity in healthy volunteers

(2011) Ciara McCabe et al.   NEUROIMAGE

Genetic variation in CYP2D6 impacts neural activation during cognitive tasks in humans

(2011) Julia C. Stingl et al.   NEUROIMAGE

Brain connectivity in psychiatric imaging genetics

(2011) Heike Tost et al.   NEUROIMAGE

Resting State Functional Connectivity in Perfusion Imaging: Correlation Maps with BOLD Connectivity and Resting State Perfusion

(2011) Roberto Viviani et al.   PLoS One

Brain-state-independent neural representation of peripheral stimulation in rat olfactory bulb

(2011) A. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytochrome P450 enzymes in the brain: emerging evidence of biological significance

(2011) Charmaine S. Ferguson et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Research Domain Criteria (RDoC): Toward a New Classification Framework for Research on Mental Disorders

(2010) Thomas Insel et al.   AMERICAN JOURNAL OF PSYCHIATRY

Effects on resting cerebral blood flow and functional connectivity induced by metoclopramide: a perfusion MRI study in healthy volunteers

(2010) María A Fernández-Seara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neurovascular Coupling in the Human Visual Cortex Is Modulated by Cyclooxygenase-1 (COX-1) Gene Variant

(2010) Tim Hahn et al.   CEREBRAL CORTEX

Quantification of Cerebral Blood Flow as Biomarker of Drug Effect: Arterial Spin Labeling phMRI After a Single Dose of Oral Citalopram

(2010) Y Chen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

What is the value of human FMRI in CNS drug development?

(2010) Richard G. Wise et al.   DRUG DISCOVERY TODAY

Prefrontal-Related Functional Connectivities within the Default Network Are Modulated by COMT val158met in Healthy Young Adults

(2010) B. Liu et al.   JOURNAL OF NEUROSCIENCE

Functional connectivity in the rat brain: a complex network approach

(2010) Angelo Bifone et al.   MAGNETIC RESONANCE IMAGING

CYP2D6 in the brain: genotype effects on resting brain perfusion

(2010) J Kirchheiner et al.   MOLECULAR PSYCHIATRY

Nicotine replacement in abstinent smokers improves cognitive withdrawal symptoms with modulation of resting brain network dynamics

(2010) David M. Cole et al.   NEUROIMAGE

Frontocingulate Dysfunction in Depression: Toward Biomarkers of Treatment Response

(2010) Diego A Pizzagalli   NEUROPSYCHOPHARMACOLOGY

Changes in Resting Neural Connectivity during Propofol Sedation

(2010) Emmanuel A. Stamatakis et al.   PLoS One

DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia

(2010) G. Blasi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward discovery science of human brain function

(2010) B. B. Biswal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging genetics: implications for research on variable antidepressant drug response

(2010) Ulrich Rabl et al.   Expert Review of Clinical Pharmacology

Roles of the Akt/GSK-3 and Wnt Signaling Pathways in Schizophrenia and Antipsychotic Drug Action

(2009) Zachary Freyberg et al.   AMERICAN JOURNAL OF PSYCHIATRY

Pharmacogenetics in Psychiatry - A Useful Clinical Tool or Wishful Thinking for the Future?

(2009) J. Kirchheiner et al.   CURRENT PHARMACEUTICAL DESIGN

The effect of daily caffeine use on cerebral blood flow: How much caffeine can we tolerate?

(2009) Merideth A. Addicott et al.   HUMAN BRAIN MAPPING

L-Dopa Modulates Functional Connectivity in Striatal Cognitive and Motor Networks: A Double-Blind Placebo-Controlled Study

(2009) C. Kelly et al.   JOURNAL OF NEUROSCIENCE

Caffeine dose effect on activation-induced BOLD and CBF responses

(2009) Yufen Chen et al.   NEUROIMAGE

Treatment with Olanzapine is Associated with Modulation of the Default Mode Network in Patients with Schizophrenia

(2009) Fabio Sambataro et al.   NEUROPSYCHOPHARMACOLOGY

From the genome to the phenome and back: linking genes with human brain function and structure using genetically informed neuroimaging

(2009) H.R. Siebner et al.   NEUROSCIENCE

Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia

(2008) Alessandro Bertolino et al.   BRAIN

Cannabinoid receptor 1 (CNR1) gene: Impact on antidepressant treatment response and emotion processing in Major Depression

(2008) Katharina Domschke et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Persistent default-mode network connectivity during light sedation

(2008) Michael D. Greicius et al.   HUMAN BRAIN MAPPING

Effect of abstinence challenge on brain function and cognition in smokers differs by COMT genotype

(2008) J Loughead et al.   MOLECULAR PSYCHIATRY

Nicotine abstinence-induced cerebral blood flow changes by genotype

(2008) Ze Wang et al.   NEUROSCIENCE LETTERS