Molecular targets of aspirin and cancer prevention

Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women

(2013) Christina A. Gamba et al.   CANCER

An Alkyne–Aspirin Chemical Reporter for the Detection of Aspirin-Dependent Protein Modification in Living Cells

(2013) Leslie A. Bateman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Determining target engagement in living systems

(2013) Gabriel M Simon et al.   Nature Chemical Biology

A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles

(2013) Chu Wang et al.   NATURE METHODS

Protein lysine acetylation guards metabolic homeostasis to fight against cancer

(2013) W Xu et al.   ONCOGENE

Functional Lysine Modification by an Intrinsically Reactive Primary Glycolytic Metabolite

(2013) R. E. Moellering et al.   SCIENCE

Aspirin and the prevention of colorectal cancer

(2012) Ángel Ferrández et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Use of Aspirin postdiagnosis improves survival for colon cancer patients

(2012) E Bastiaannet et al.   BRITISH JOURNAL OF CANCER

Use of aspirin, but not other non-steroidal anti-inflammatory drugs is associated with decreased prostate cancer risk at the population level

(2012) Thea Veitonmäki et al.   EUROPEAN JOURNAL OF CANCER

The Mechanisms of RNA SHAPE Chemistry

(2012) Jennifer L. McGinnis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nonsteroidal Anti-inflammatory Drug Use, Chronic Liver Disease, and Hepatocellular Carcinoma

(2012) Vikrant V. Sahasrabuddhe et al.   JNCI-Journal of the National Cancer Institute

Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials

(2012) Peter M Rothwell et al.   LANCET

The role of aspirin in cancer prevention

(2012) Michael J. Thun et al.   Nature Reviews Clinical Oncology

Aspirin Use, TumorPIK3CAMutation, and Colorectal-Cancer Survival

(2012) Xiaoyun Liao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aspirin Inhibits Colon Cancer Cell and Tumor Growth and Downregulates Specificity Protein (Sp) Transcription Factors

(2012) Satya Pathi et al.   PLoS One

Will an Aspirin a Day Keep Cancer Away?

(2012) J. Kaiser   SCIENCE

Aspirin Intake and Survival After Breast Cancer

(2010) Michelle D. Holmes et al.   JOURNAL OF CLINICAL ONCOLOGY

Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials

(2010) Peter M Rothwell et al.   LANCET

Human tissue transglutaminase is inhibited by pharmacologic and chemical acetylation

(2010) Thung S. Lai et al.   PROTEIN SCIENCE

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

(2010) Q. Wang et al.   SCIENCE

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Aspirin Use and Survival After Diagnosis of Colorectal Cancer

(2009) Andrew T. Chan   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Direct Raman Measurement of an Elevated Base pKain the Active Site of a Small Ribozyme in a Precatalytic Conformation

(2009) Man Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

(2009) Bryson D Bennett et al.   Nature Chemical Biology

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity

(2008) Guilherme A. Spitz et al.   BIOCHEMICAL PHARMACOLOGY

Non-steroidal anti-inflammatory drugs suppress the ERK signaling pathway via block of Ras/c-Raf interaction and activation of MAP kinase phosphatases

(2008) Mei-Ren Pan et al.   CELLULAR SIGNALLING