Mechanisms, regulation and consequences of protein SUMOylation

Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3

(2010) Mei-Ling Kuo et al.   CELL CYCLE

The SUMO E3 Ligase Activity of Pc2 Is Coordinated through a SUMO Interaction Motif

(2010) S. h. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

A Role for Non-Covalent SUMO Interaction Motifs in Pc2/CBX4 E3 Activity

(2010) Jacqueline C. Merrill et al.   PLoS One

Characterization of SENP7, a SUMO-2/3-specific isopeptidase

(2009) Lin Nan Shen et al.   BIOCHEMICAL JOURNAL

Sumo-2/3-ylation following in vitro modeled ischemia is reduced in delayed ischemic tolerance

(2009) Liam T. Loftus et al.   BRAIN RESEARCH

SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation

(2009) Chao Huang et al.   EMBO JOURNAL

MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission

(2009) Emélie Braschi et al.   EMBO REPORTS

SUMOylation participates in induction of ischemic tolerance

(2009) Yang ja Lee et al.   JOURNAL OF NEUROCHEMISTRY

Differential SUMOylation of LXRα and LXRβ Mediates Transrepression of STAT1 Inflammatory Signaling in IFN-γ-Stimulated Brain Astrocytes

(2009) Jee Hoon Lee et al.   MOLECULAR CELL

Direct Binding of CoREST1 to SUMO-2/3 Contributes to Gene-Specific Repression by the LSD1/CoREST1/HDAC Complex

(2009) Jian Ouyang et al.   MOLECULAR CELL

Protection from Isopeptidase-Mediated Deconjugation Regulates Paralog-Selective Sumoylation of RanGAP1

(2009) Shanshan Zhu et al.   MOLECULAR CELL

Phospho-Regulated SUMO Interaction Modules Connect the SUMO System to CK2 Signaling

(2009) Per Stehmeier et al.   MOLECULAR CELL

An additional role for SUMO in ubiquitin-mediated proteolysis

(2009) Marie-Claude Geoffroy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitin-binding domains — from structures to functions

(2009) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9

(2009) Firaz Mohideen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ebp1 sumoylation, regulated by TLS/FUS E3 ligase, is required for its anti-proliferative activity

(2009) S-M Oh et al.   ONCOGENE

Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity

(2009) S. Subramaniam et al.   SCIENCE

System-Wide Changes to SUMO Modifications in Response to Heat Shock

(2009) F. Golebiowski et al.   Science Signaling

A stress-dependent SUMO4 sumoylation of its substrate proteins

(2008) Wenzhong Wei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SUMO, hypoxia and the regulation of metabolism: Figure 1

(2008) Terence A. Agbor et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

SUMO under stress: Figure 1

(2008) Denis Tempé et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Identification of Phosphorylation Sites of TOPORS and a Role for Serine 98 in the Regulation of Ubiquitin but Not SUMO E3 Ligase Activity†

(2008) Hye-Jin Park et al.   BIOCHEMISTRY

A novel method for high accuracy sumoylation site prediction from protein sequences

(2008) Jialin Xu et al.   BMC BIOINFORMATICS

Extracellular Signal-Regulated Kinase 5 SUMOylation Antagonizes Shear Stress–Induced Antiinflammatory Response and Endothelial Nitric Oxide Synthase Expression in Endothelial Cells

(2008) Chang-Hoon Woo et al.   CIRCULATION RESEARCH

Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML

(2008) Stefan R. Weisshaar et al.   FEBS LETTERS

Small Ubiquitin-related Modifier (SUMO) Binding Determines Substrate Recognition and Paralog-selective SUMO Modification

(2008) Jianmei Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUMOylation and De-SUMOylation: Wrestling with Life's Processes

(2008) Edward T. H. Yeh   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3

(2008) E. Evdokimov et al.   JOURNAL OF CELL SCIENCE

Transient Focal Cerebral Ischemia Induces a Dramatic Activation of Small Ubiquitin-Like Modifier Conjugation

(2008) Wei Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cerebral ischemiastroke and small ubiquitin-like modifier (SUMO) conjugation a new target for therapeutic intervention?

(2008) Wei Yang et al.   JOURNAL OF NEUROCHEMISTRY

Phosphorylation of SUMO-1 Occursin Vivoand Is Conserved through Evolution

(2008) Ivan Matic et al.   JOURNAL OF PROTEOME RESEARCH

Sumo-1 Function Is Dispensable in Normal Mouse Development

(2008) F.-P. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone Deacetylase 7 Promotes PML Sumoylation and Is Essential for PML Nuclear Body Formation

(2008) C. Gao et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanism and Consequences for Paralog-Specific Sumoylation of Ubiquitin-Specific Protease 25

(2008) Erik Meulmeester et al.   MOLECULAR CELL

Ubc9 Sumoylation Regulates SUMO Target Discrimination

(2008) Puck Knipscheer et al.   MOLECULAR CELL

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

Investigating the Mechanisms Underlying Neuronal Death in Ischemia Using In Vitro Oxygen-Glucose Deprivation: Potential Involvement of Protein SUMOylation

(2008) Helena Cimarosti et al.   NEUROSCIENTIST

A SIM-ultaneous role for SUMO and ubiquitin

(2008) J. Jefferson P. Perry et al.   TRENDS IN BIOCHEMICAL SCIENCES

Increased protein SUMOylation following focal cerebral ischemia

(2007) Helena Cimarosti et al.   NEUROPHARMACOLOGY