Activating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Activating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma
Authors
Keywords
-
Journal
BRITISH JOURNAL OF CANCER
Volume 108, Issue 1, Pages 72-81
Publisher
Springer Nature
Online
2012-12-21
DOI
10.1038/bjc.2012.559
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Efficacy and Safety of Sorafenib in Advanced Hepatocellular Carcinoma Under Daily Practice Conditions
- (2014) M.W. Welker et al. JOURNAL OF CHEMOTHERAPY
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism
- (2011) Y. Zhao et al. CANCER RESEARCH
- Serial Magnetic Resonance Spectroscopy Reveals a Direct Metabolic Effect of Cediranib in Glioblastoma
- (2011) H. Kim et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Management of hepatocellular carcinoma: An update
- (2011) Jordi Bruix et al. HEPATOLOGY
- Higher discontinuation and lower survival rates are likely in elderly Japanese patients with advanced hepatocellular carcinoma receiving sorafenib
- (2011) Manabu Morimoto et al. HEPATOLOGY RESEARCH
- Treatment Monitoring in Gliomas
- (2011) Jonathan Vöglein et al. INVESTIGATIVE RADIOLOGY
- Prognostic value of 18F-FDG PET for hepatocellular carcinoma patients treated with sorafenib
- (2011) Jae Hoon Lee et al. LIVER INTERNATIONAL
- Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells
- (2011) Ramon C Sun et al. Molecular Cancer
- Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?
- (2011) A Lemarie et al. ONCOGENE
- Exploiting Mitochondrial Dysfunction for Effective Elimination of Imatinib-Resistant Leukemic Cells
- (2011) Jérome Kluza et al. PLoS One
- In vivomagnetic resonance spectroscopy of liver tumors and metastases
- (2011) EGW ter Voert WORLD JOURNAL OF GASTROENTEROLOGY
- Induction of DNA Damage-Inducible Gene GADD45 Contributes to Sorafenib-Induced Apoptosis in Hepatocellular Carcinoma Cells
- (2010) D.-L. Ou et al. CANCER RESEARCH
- Oligomycin-induced Bioenergetic Adaptation in Cancer Cells with Heterogeneous Bioenergetic Organization
- (2010) Wenshan Hao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming
- (2010) F Zhao et al. ONCOGENE
- Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors
- (2010) Luigi Fiume et al. PHARMACOLOGICAL RESEARCH
- Metabolic Modulation of Glioblastoma with Dichloroacetate
- (2010) E. D. Michelakis et al. Science Translational Medicine
- Magnetic resonance spectroscopy to study hepatic metabolism in diffuse liver diseases, diabetes and cancer
- (2010) Pieter C Dagnelie WORLD JOURNAL OF GASTROENTEROLOGY
- GLUT1 Expression Is Increased in Hepatocellular Carcinoma and Promotes Tumorigenesis
- (2009) Thomas Amann et al. AMERICAN JOURNAL OF PATHOLOGY
- Abnormalities in Glucose Uptake and Metabolism in Imatinib-Resistant Human BCR-ABL-Positive Cells
- (2009) D. J. Kominsky et al. CLINICAL CANCER RESEARCH
- Induction of Bim Expression Contributes to the Antitumor Synergy Between Sorafenib and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Inhibitor CI-1040 in Hepatocellular Carcinoma
- (2009) D.-L. Ou et al. CLINICAL CANCER RESEARCH
- GLUT1 as a therapeutic target in hepatocellular carcinoma
- (2009) Thomas Amann et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- 2-[18f]-2-deoxy-d-glucose (fdg) uptake in human tumor cells is related to the expression of glut-1 and hexokinase ii
- (2008) L.-C. Ong et al. ACTA RADIOLOGICA
- Role of dichloroacetate in the treatment of genetic mitochondrial diseases☆
- (2008) Peter W. Stacpoole et al. ADVANCED DRUG DELIVERY REVIEWS
- Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells
- (2008) E. Hulleman et al. BLOOD
- Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
- (2008) E D Michelakis et al. BRITISH JOURNAL OF CANCER
- Tumor Cell Metabolism: Cancer's Achilles' Heel
- (2008) Guido Kroemer et al. CANCER CELL
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
- (2008) Ann-Lii Cheng et al. LANCET ONCOLOGY
- Sorafenib in Advanced Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. NEW ENGLAND JOURNAL OF MEDICINE
- Quantitative evaluation of dichloroacetic acid kinetics in human—a physiologically based pharmacokinetic modeling investigation
- (2007) Ting Li et al. TOXICOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now