Oncolytic Herpes Simplex Virus 1 Encoding 15-Prostaglandin Dehydrogenase Mitigates Immune Suppression and Reduces Ectopic Primary and Metastatic Breast Cancer in Mice

Loss of 15-Hydroxyprostaglandin Dehydrogenase Expression Contributes to Bladder Cancer Progression

(2010) Stephanie Tseng-Rogenski et al.   AMERICAN JOURNAL OF PATHOLOGY

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity

(2010) Suzanne Ostrand-Rosenberg   CANCER IMMUNOLOGY IMMUNOTHERAPY

Phase I/II Study of Oncolytic Herpes Simplex Virus NV1020 in Patients with Extensively Pretreated Refractory Colorectal Cancer Metastatic to the Liver

(2010) Sunil K. Geevarghese et al.   HUMAN GENE THERAPY

The Virion Host Shut-Off (vhs) Protein Blocks a TLR-Independent Pathway of Herpes Simplex Virus Type 1 Recognition in Human and Mouse Dendritic Cells

(2010) Christopher R. Cotter et al.   PLoS One

Reduction of 15-hydroxyprostaglandin dehydrogenase expression is an independent predictor of poor survival associated with enhanced cell proliferation in gastric adenocarcinoma

(2009) Hiroshi Tatsuwaki et al.   CANCER SCIENCE

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

The Case of Oncolytic Viruses Versus the Immune System: Waiting on the Judgment of Solomon

(2009) Robin J. Prestwich et al.   HUMAN GENE THERAPY

Altered Expression of 15-Hydroxyprostaglandin Dehydrogenase in Tumor-Infiltrated CD11b Myeloid Cells: A Mechanism for Immune Evasion in Cancer

(2009) E. Eruslanov et al.   JOURNAL OF IMMUNOLOGY

Experimental cancer therapy using restoration of NAD+-linked 15-hydroxyprostaglandin dehydrogenase expression

(2009) L. N. Kaliberova et al.   MOLECULAR CANCER THERAPEUTICS

Suppression of Invasive Properties of Colorectal Carcinoma SW480 Cells by 15-Hydroxyprostaglandin Dehydrogenase Gene

(2008) Meining Li et al.   CANCER INVESTIGATION

Immune surveillance: a balance between protumor and antitumor immunity

(2008) Suzanne Ostrand-Rosenberg   CURRENT OPINION IN GENETICS & DEVELOPMENT

Herpes simplex virus NV1020 as a novel and promising therapy for hepatic malignancy

(2008) Kaitlyn J Kelly et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Herpes Simplex Virus Virion Host Shutoff Attenuates Establishment of the Antiviral State

(2008) T. J. Pasieka et al.   JOURNAL OF VIROLOGY

Herpes simplex virus type-1(HSV-1) oncolytic and highly fusogenic mutants carrying the NV1020 genomic deletion effectively inhibit primary and metastatic tumors in mice

(2008) Anna Israyelyan et al.   Virology Journal