Expressions of individual PHDs associate with good prognostic factors and increased proliferation in breast cancer patients

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

PHD3 regulates differentiation, tumour growth and angiogenesis in pancreatic cancer

(2010) Y Su et al.   BRITISH JOURNAL OF CANCER

Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth

(2010) Terhi Jokilehto et al.   EXPERIMENTAL CELL RESEARCH

Expression of key hypoxia sensing prolyl-hydroxylases PHD1, -2 and -3 in pancreaticobiliary cancer

(2010) Lucy Gossage et al.   HISTOPATHOLOGY

HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression

(2010) Daniel A. Tennant et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase

(2009) Qing Zhang et al.   CANCER CELL

Prolyl Hydroxylases 2 and 3 Act in Gliomas as Protective Negative Feedback Regulators of Hypoxia-Inducible Factors

(2009) A.-T. Henze et al.   CANCER RESEARCH

HIF Prolyl 4-Hydroxylases and their Potential as Drug Targets

(2009) Johanna Myllyharju   CURRENT PHARMACEUTICAL DESIGN

Prolyl Hydroxylase-3 Is Down-regulated in Colorectal Cancer Cells and Inhibits IKKβ Independent of Hydroxylase Activity

(2009) Jing Xue et al.   GASTROENTEROLOGY

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

(2009) Gregg L. Semenza   PHYSIOLOGY

Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets

(2008) Johanna Myllyharju   ANNALS OF MEDICINE

Hypoxia-Inducible Factor-2  Correlates to Distant Recurrence and Poor Outcome in Invasive Breast Cancer

(2008) K. Helczynska et al.   CANCER RESEARCH

Biology of HIF-1α

(2008) A Weidemann et al.   CELL DEATH AND DIFFERENTIATION

The kinesin KIF1B  acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor

(2008) S. Schlisio et al.   GENES & DEVELOPMENT

Prolyl Hydroxylase PHD3 Activates Oxygen-dependent Protein Aggregation

(2008) Krista Rantanen et al.   MOLECULAR BIOLOGY OF THE CELL

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL