Effects of simvastatin/ezetimibe on microparticles, endothelial progenitor cells and platelet aggregation in subjects with coronary heart disease under antiplatelet therapy

Effects of simvastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, after oral and intravenous administration in rats: possible role of P-glycoprotein and CYP3A4 inhibition by simvastatin

(2014) Choi Dong-Hyun et al.   Pharmacological Reports

The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials

(2013)   LANCET

High-dose statin monotherapy versus low-dose statin/ezetimibe combination on fasting and postprandial lipids and endothelial function in obese patients with the metabolic syndrome: The PANACEA study

(2012) Jan Westerink et al.   ATHEROSCLEROSIS

Differences in synthesis and absorption of cholesterol of two effective lipid-lowering therapies

(2012) S.H. Kasmas et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study

(2012) Yongwhi Park et al.   EUROPEAN HEART JOURNAL

Simvastatin interactions with other drugs

(2012) Matilda Florentin et al.   Expert Opinion On Drug Safety

C-reactive protein down-regulates endothelial nitric oxide synthase expression and promotes apoptosis in endothelial progenitor cells through receptor for advanced glycation end-products

(2012) Jianfei Chen et al.   GENE

Pharmacokinetic interactions between clopidogrel and rosuvastatin: Effects on vascular protection in subjects with coronary heart disease

(2012) Luiz F. Pinheiro et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Reduced number and impaired function of circulating endothelial progenitor cells in patients with abdominal aortic aneurysm

(2012) Shih-Hsien Sung et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Impact of a cardiac rehabilitation program and inflammatory state on endothelial progenitor cells in acute coronary syndrome patients

(2012) Francesca Cesari et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Imbalance between endothelial progenitors cells and microparticles in HIV-infected patients naive for antiretroviral therapy

(2011) Erika F.R. da Silva et al.   AIDS

Cytochromes P450 Catalyze Both Steps of the Major Pathway of Clopidogrel Bioactivation, whereas Paraoxonase Catalyzes the Formation of a Minor Thiol Metabolite Isomer

(2011) Patrick M. Dansette et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Endothelial Progenitor Cell Mobilization and Platelet Microparticle Release Are Influenced by Clopidogrel Plasma Levels in Stable Coronary Artery Disease

(2011) Carolina N. França et al.   CIRCULATION JOURNAL

Antiplatelet agents for the treatment and prevention of atherothrombosis

(2011) Carlo Patrono et al.   EUROPEAN HEART JOURNAL

ESC/EAS Guidelines for the management of dyslipidaemias: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)

(2011) et al.   EUROPEAN HEART JOURNAL

Darbepoetin improves endothelial function and increases circulating endothelial progenitor cell number in patients with coronary artery disease

(2011) C. Mueller et al.   HEART

Assessment of flow-mediated dilation in humans: a methodological and physiological guideline

(2010) Dick H. J. Thijssen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Pleiotropic Effects of Statins

(2010) Qian Zhou et al.   CIRCULATION JOURNAL

Increased circulating CD31+/annexin V+ apoptotic microparticles and decreased circulating endothelial progenitor cell levels in hypertensive patients with microalbuminuria

(2010) Po-Hsun Huang et al.   JOURNAL OF HYPERTENSION

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

(2010)   LANCET

Does Simvastatin Cause More Myotoxicity Compared with Other Statins?

(2009) James M Backes et al.   ANNALS OF PHARMACOTHERAPY

Circulating level of microparticles and their correlation with arterial elasticity and endothelium-dependent dilation in patients with type 2 diabetes mellitus

(2009) Bo Feng et al.   ATHEROSCLEROSIS

Statins and Cardiovascular Diseases: From Cholesterol Lowering to Pleiotropy

(2009) Qian Zhou et al.   CURRENT PHARMACEUTICAL DESIGN

Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): Comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes

(2008) Christopher P. Cannon et al.   AMERICAN HEART JOURNAL

Pharmacogenomics and Drug Toxicity

(2008) Yusuke Nakamura   NEW ENGLAND JOURNAL OF MEDICINE