Effects of simvastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, after oral and intravenous administration in rats: possible role of P-glycoprotein and CYP3A4 inhibition by simvastatin

Title
Effects of simvastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, after oral and intravenous administration in rats: possible role of P-glycoprotein and CYP3A4 inhibition by simvastatin
Authors
Keywords
-
Journal
Pharmacological Reports
Volume 63, Issue 6, Pages 1574-1582
Publisher
Elsevier BV
Online
2014-02-20
DOI
10.1016/s1734-1140(11)70724-1

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