A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats

Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model

(2012) Zacharias Kohl et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of α-synucleinopathy

(2012) Kiren Ubhi et al.   EXPERIMENTAL NEUROLOGY

α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion

(2012) Hodaka Yamakado et al.   NEUROSCIENCE RESEARCH

Impaired neurotransmission caused by overexpression of  -synuclein in nigral dopamine neurons

(2012) M. Lundblad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons

(2011) Grit Taschenberger et al.   ACTA NEUROPATHOLOGICA

Three-dimensional motion analysis of postural adjustments during over-ground locomotion in a rat model of Parkinson's disease

(2011) June K. Madete et al.   BEHAVIOURAL BRAIN RESEARCH

Longitudinal evolution of compensatory changes in striatal dopamine processing in Parkinson's disease

(2011) Ramachandiran Nandhagopal et al.   BRAIN

Dynamic regulation of dopamine and serotonin responses to salient stimuli during chronic haloperidol treatment

(2011) Davide Amato et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

 -Syn Suppression Reverses Synaptic and Memory Defects in a Mouse Model of Dementia with Lewy Bodies

(2011) Y. Lim et al.   JOURNAL OF NEUROSCIENCE

Olfactory neuron-specific expression of A30P alpha-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages

(2011) Silke Nuber et al.   NEUROBIOLOGY OF DISEASE

α-synuclein phosphorylation and truncation are normal events in the adult human brain

(2011) G. Muntané et al.   NEUROSCIENCE

Progressive Neurodegeneration or Endogenous Compensation in an Animal Model of Parkinson's Disease Produced by Decreasing Doses of Alpha-Synuclein

(2011) James B. Koprich et al.   PLoS One

Neuropathology in Mice Expressing Mouse Alpha-Synuclein

(2011) Claus Rieker et al.   PLoS One

Improved Immunodetection of Endogenous α-Synuclein

(2011) Byung Rho Lee et al.   PLoS One

In vivo demonstration that  -synuclein oligomers are toxic

(2011) B. Winner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antidepressant-like properties of sarizotan in experimental Parkinsonism

(2011) Xiaoqun Zhang et al.   PSYCHOPHARMACOLOGY

α-Synucleinopathy in the human olfactory system in Parkinson’s disease: involvement of calcium-binding protein- and substance P-positive cells

(2010) Isabel Ubeda-Bañon et al.   ACTA NEUROPATHOLOGICA

Clinical progression in Parkinson disease and the neurobiology of axons

(2010) Hsiao-Chun Cheng et al.   ANNALS OF NEUROLOGY

Imaging dopamine transporters in Parkinson’s disease

(2010) David J Brooks   Biomarkers in Medicine

Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated α-synuclein gene mutations precede central nervous system changes

(2010) Yien-Ming Kuo et al.   HUMAN MOLECULAR GENETICS

Neurodegeneration in a Transgenic Mouse Model of Multiple System Atrophy Is Associated with Altered Expression of Oligodendroglial-Derived Neurotrophic Factors

(2010) K. Ubhi et al.   JOURNAL OF NEUROSCIENCE

Methylation Regulates Alpha-Synuclein Expression and Is Decreased in Parkinson's Disease Patients' Brains

(2010) A. Jowaed et al.   JOURNAL OF NEUROSCIENCE

Clinical course of the first Asian family with Parkinsonism related to SNCA triplication

(2010) Takeshi Sekine et al.   MOVEMENT DISORDERS

Behavioral, Neurochemical, and Electrophysiological Changes in an Early Spontaneous Mouse Model of Nigrostriatal Degeneration

(2010) Paola Sgadò et al.   NEUROTOXICITY RESEARCH

CpG Demethylation Enhances Alpha-Synuclein Expression and Affects the Pathogenesis of Parkinson's Disease

(2010) Lumine Matsumoto et al.   PLoS One

Is adult neurogenesis essential for olfaction?

(2010) Françoise Lazarini et al.   TRENDS IN NEUROSCIENCES

Risk is in the Air

(2009) Rui D. S. Prediger et al.   Annals of the New York Academy of Sciences

Detection of elevated levels of soluble  -synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies

(2009) K. E. Paleologou et al.   BRAIN

Longitudinal progression of sporadic Parkinson's disease: a multi-tracer positron emission tomography study

(2009) R. Nandhagopal et al.   BRAIN

Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein

(2009) Franz Marxreiter et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Forebrain overexpression of α-synuclein leads to early postnatal hippocampal neuron loss and synaptic disruption

(2009) Youngshin Lim et al.   EXPERIMENTAL NEUROLOGY

Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV  -Synucleinopathy

(2009) C. Y. Chung et al.   JOURNAL OF NEUROSCIENCE

A Multitracer Dopaminergic PET Study of Young-Onset Parkinsonian Patients With and Without Parkin Gene Mutations

(2009) M.-J. Ribeiro et al.   JOURNAL OF NUCLEAR MEDICINE

Conditional transgenic mice expressing C-terminally truncated human α-synuclein (αSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons

(2009) João Daher et al.   Molecular Neurodegeneration

Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease

(2009) Cassia R. Overk et al.   NEUROBIOLOGY OF DISEASE

Calcium signaling cascade links dopamine D1–D2 receptor heteromer to striatal BDNF production and neuronal growth

(2009) Ahmed Hasbi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal plasticity: A link between stress and mood disorders

(2009) Francesca Calabrese et al.   PSYCHONEUROENDOCRINOLOGY

Sexually dimorphic enhancement by estradiol of male urinary odor detection thresholds in mice.

(2008) Krystina G. Sorwell et al.   BEHAVIORAL NEUROSCIENCE

Incidence and Extent of Lewy Body-Related α-Synucleinopathy in Aging Human Olfactory Bulb

(2008) Renpei Sengoku et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neurodegeneration and Motor Dysfunction in a Conditional Model of Parkinson's Disease

(2008) S. Nuber et al.   JOURNAL OF NEUROSCIENCE

Dopaminergic mesencephalic systems and behavioral performance in very old rats

(2008) H.L. Sanchez et al.   NEUROSCIENCE

Inhibition of α-Synuclein Fibrillization by Dopamine Is Mediated by Interactions with Five C-Terminal Residues and with E83 in the NAC Region

(2008) Fernando E. Herrera et al.   PLoS One

Role of medial prefrontal, entorhinal, and occipital 5-HT in cocaine-induced place preference and hyperlocomotion: evidence for multiple dissociations

(2008) M. E. Pum et al.   PSYCHOPHARMACOLOGY

Generation of a α-synuclein-based rat model of Parkinson's disease

(2007) Alessandra Recchia et al.   NEUROBIOLOGY OF DISEASE

Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein in mice

(2006) Masaki Wakamatsu et al.   NEUROBIOLOGY OF AGING