Quantitative clinical pharmacology for size and age scaling in pediatric drug development: A systematic review

Preclinical pharmacokinetics and disposition of a novel selective VEGFR inhibitor Fruquintinib (HMPL-013) and the prediction of its human pharmacokinetics

(2014) Yi Gu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Population Pharmacokinetics of Bevacizumab in Children with Osteosarcoma: Implications for Dosing

(2014) D. C. Turner et al.   CLINICAL CANCER RESEARCH

Warfarin dose prediction in children using pharmacometric bridging—comparison with published pharmacogenetic dosing algorithms

(2013) Anna-Karin Hamberg et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Integration of preclinical and clinical knowledge to predict intravenous PK in human: Bilastine case study

(2013) Valvanera Vozmediano et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Adolescent Dosing and Labeling Since the Food and Drug Administration Amendments Act of 2007

(2013) Jeremiah D. Momper et al.   JAMA Pediatrics

A Guide to Rational Dosing of Monoclonal Antibodies

(2012) Shuang Bai et al.   CLINICAL PHARMACOKINETICS

Development of a Physiologically Based Model for Oseltamivir and Simulation of Pharmacokinetics in Neonates and Infants

(2011) Neil Parrott et al.   CLINICAL PHARMACOKINETICS

Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human

(2011) Dhaval K. Shah et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Innovative clinical trial design for pediatric therapeutics

(2011) Matthew M Laughon et al.   Expert Review of Clinical Pharmacology

Interspecies Scaling for the Prediction of Drug Clearance in Children

(2010) Iftekhar Mahmood   CLINICAL PHARMACOKINETICS

Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review

(2010) P Zhao et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Application of allometry principles for the prediction of human pharmacokinetic parameters for irbesartan, a AT1 receptor antagonist, from animal data

(2010) Venkata V. Pavan Kumar et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice

(2010) Trevor N. Johnson et al.   PEDIATRIC ANESTHESIA

Drug Development for Pediatric Populations: Regulatory Aspects

(2010) Jochen Zisowsky et al.   Pharmaceutics

Development of a PBPK Model for Monoclonal Antibodies and Simulation of Human and Mice PBPK of a Radiolabelled Monoclonal Antibody

(2009) Tomi Heiskanen et al.   CURRENT PHARMACEUTICAL DESIGN

Interspecies scaling of a camptothecin analogue: Human predictions for intravenous topotecan using animal data

(2008) P. Ahlawat et al.   XENOBIOTICA

The problems in scaling adult drug doses to children

(2007) T N Johnson   ARCHIVES OF DISEASE IN CHILDHOOD

A physiologically based pharmacokinetic (PBPK) model to characterize and predict the disposition of monoclonal antibody CC49 and its single chain Fv constructs

(2007) Jasmine P. Davda et al.   INTERNATIONAL IMMUNOPHARMACOLOGY