A novel CRTH2 antagonist: Single- and multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ACT-453859 in healthy subjects

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(2014) Z. Diamant et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Role of prostaglandin D2and CRTH2 blockade in early- and late-phase nasal responses

(2014) Y. Shiraishi et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Single- and multiple-dose tolerability and pharmacokinetics of the CRTH2 antagonist setipiprant in healthy male subjects

(2014) Patricia N. Sidharta et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Anti-eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis

(2013) A. Straumann et al.   ALLERGY

Setipiprant, a Selective Oral Antagonist of Human CRTH2: Relative Bioavailability of a Capsule and a Tablet Formulation in Healthy Female and Male Subjects

(2013) Daniela Baldoni et al.   CLINICAL THERAPEUTICS

Advances in adult asthma diagnosis and treatment in 2013

(2013) Andrea J. Apter   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inhibition of the asthmatic allergen challenge response by the CRTH2 antagonist OC000459

(2012) D. Singh et al.   EUROPEAN RESPIRATORY JOURNAL

A randomized, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma

(2011) N. Barnes et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Pharmacodynamics, Pharmacokinetics, and Safety of AM211: A Novel and Potent Antagonist of the Prostaglandin D2Receptor Type 2

(2011) G. Bain et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 Revision

(2010) Jan L. Brożek et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis

(2009) George Philip et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Evaluation of Methods for Estimating Time to Steady State with Examples from Phase 1 Studies

(2008) Lata Maganti et al.   AAPS Journal

Prostaglandin D2 Receptors DP and CRTH2 in the Pathogenesis of Asthma

(2008) Masafumi Arima et al.   CURRENT MOLECULAR MEDICINE