A randomized, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma

CRTH2 Plays an Essential Role in the Pathophysiology of Cry j 1-Induced Pollinosis in Mice

(2014) R. Nomiya et al.   JOURNAL OF IMMUNOLOGY

Interaction between prostaglandin D2and chemoattractant receptor-homologous molecule expressed on Th2 cells mediates cytokine production by Th2 lymphocytes in response to activated mast cells

(2009) L. Xue et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation

(2008) Nicholas W. Lukacs et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

CRTH2-dependent, STAT6-independent induction of cedar pollen dermatitis

(2008) M. Oiwa et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms

(2008) S. A. Boehme et al.   INTERNATIONAL IMMUNOLOGY

A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation

(2008) S. A. Boehme et al.   INTERNATIONAL IMMUNOLOGY