Toward modular biological models: defining analog modules based on referent physiological mechanisms

The development of a fully-integrated immune response model (FIRM) simulator of the immune response through integration of multiple subset models

(2013) Sirus Palsson et al.   BMC Systems Biology

Identifying reaction modules in metabolic pathways: bioinformatic deduction and experimental validation of a new putative route in purine catabolism

(2013) Matthieu Barba et al.   BMC Systems Biology

Agent-based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity

(2013) C. Anthony Hunt et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Enabling Clearance Predictions to Emerge from In Silico Actions of Quasi-Autonomous Hepatocyte Components

(2011) S. Sheikh-Bahaei et al.   DRUG METABOLISM AND DISPOSITION

On the general mechanism of selective induction of cytochrome P450 enzymes by chemicals: some theoretical considerations

(2010) Bao Ting Zhu   Expert Opinion on Drug Metabolism & Toxicology

ProMoT: modular modeling for systems biology

(2009) Sebastian Mirschel et al.   BIOINFORMATICS

Not all quiet on the noise front

(2009) Emma McCullagh et al.   Nature Chemical Biology

At the Biological Modeling and Simulation Frontier

(2009) C. Anthony Hunt et al.   PHARMACEUTICAL RESEARCH

Thinking Again about Biological Mechanisms

(2009) Lindley Darden   PHILOSOPHY OF SCIENCE

Agent-based models in translational systems biology

(2009) Gary An et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Discovering Plausible Mechanistic Details of Hepatic Drug Interactions

(2008) T. N. Lam et al.   DRUG METABOLISM AND DISPOSITION

Complexity and modularity of intracellular networks: a systematic approach for modelling and simulation

(2008) M.L. Blinov et al.   IET Systems Biology

Programming with models: modularity and abstraction provide powerful capabilities for systems biology

(2008) A. Mallavarapu et al.   Journal of the Royal Society Interface