Modeling heterogeneous responsiveness of intrinsic apoptosis pathway

Model composition through model reduction: a combined model of CD95 and NF-κB signaling pathways

(2013) Elena Kutumova et al.   BMC Systems Biology

Analysis of a mathematical model of apoptosis: individual differences and malfunction in programmed cell death

(2013) Elife Zerrin Bagci et al.   JOURNAL OF CLINICAL MONITORING AND COMPUTING

Targeting IAP proteins for therapeutic intervention in cancer

(2012) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Intrinsic Noise Analyzer: A Software Package for the Exploration of Stochastic Biochemical Kinetics Using the System Size Expansion

(2012) Philipp Thomas et al.   PLoS One

Interplay between gene expression noise and regulatory network architecture

(2012) Guilhem Chalancon et al.   TRENDS IN GENETICS

Measuring and Modeling Apoptosis in Single Cells

(2011) Sabrina L. Spencer et al.   CELL

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

Robust Network Topologies for Generating Switch-Like Cellular Responses

(2011) Najaf A. Shah et al.   PLoS Computational Biology

Bcl-2 inhibits apoptosis by increasing the time-to-death and intrinsic cell-to-cell variations in the mitochondrial pathway of cell death

(2010) Joanna Skommer et al.   APOPTOSIS

Mathematical modelling of the mitochondrial apoptosis pathway

(2010) Heinrich J. Huber et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Estimating the Stochastic Bifurcation Structure of Cellular Networks

(2010) Carl Song et al.   PLoS Computational Biology

Computational Analysis of Dynamical Responses to the Intrinsic Pathway of Programmed Cell Death

(2009) Tongli Zhang et al.   BIOPHYSICAL JOURNAL

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

(2009) Sabrina L. Spencer et al.   NATURE

Exploring the roles of noise in the eukaryotic cell cycle

(2009) S. Kar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determining biological noise via single cell analysis

(2008) Edgar A. Arriaga   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Monte Carlo Simulation of Cell Death Signaling Predicts Large Cell-to-Cell Stochastic Fluctuations through the Type 2 Pathway of Apoptosis

(2008) Subhadip Raychaudhuri et al.   BIOPHYSICAL JOURNAL

Strong negative self regulation of Prokaryotic transcription factors increases the intrinsic noise of protein expression

(2008) Dov J Stekel et al.   BMC Systems Biology

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

(2008) John G. Albeck et al.   MOLECULAR CELL