Disentangling function from topology to infer the network properties of disease genes

Removing bias against membrane proteins in interaction networks

(2011) Glauber C Brito et al.   BMC Systems Biology

Vavien: An Algorithm for Prioritizing Candidate Disease Genes Based on Topological Similarity of Proteins in Interaction Networks

(2011) Sinan Erten et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

The Impact of Multifunctional Genes on "Guilt by Association" Analysis

(2011) Jesse Gillis et al.   PLoS One

Broker Genes in Human Disease

(2010) James J. Cai et al.   Genome Biology and Evolution

IntOGen: integration and data mining of multidimensional oncogenomic data

(2010) Gunes Gundem et al.   NATURE METHODS

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

HitPredict: a database of quality assessed protein–protein interactions in nine species

(2010) Ashwini Patil et al.   NUCLEIC ACIDS RESEARCH

How and when should interactome-derived clusters be used to predict functional modules and protein function?

(2009) Jimin Song et al.   BIOINFORMATICS

Systems-level cancer gene identification from protein interaction network topology applied to melanogenesis-related functional genomics data

(2009) T. Milenkovic et al.   Journal of the Royal Society Interface

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Protein networks in disease

(2008) T. Ideker et al.   GENOME RESEARCH

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Network properties of genes harboring inherited disease mutations

(2008) I. Feldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An integrated approach to inferring gene-disease associations in humans

(2008) Predrag Radivojac et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Low duplicability and network fragility of cancer genes

(2008) Davide Rambaldi et al.   TRENDS IN GENETICS

Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality

(2008) Elena Zotenko et al.   PLoS Computational Biology