Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer

NOX2 (gp91phox) is a predominant O2 sensor in a human airway chemoreceptor cell line: biochemical, molecular, and electrophysiological evidence

(2012) Josef Buttigieg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The B-cell receptor signaling pathway as a therapeutic target in CLL

(2012) J. A. Woyach et al.   BLOOD

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

(2012) Martin Peifer et al.   NATURE GENETICS

Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1

(2012) Lauren Averett Byers et al.   Cancer Discovery

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

(2012) Purvesh Khatri et al.   PLoS Computational Biology

Supporting tool suite for production proteomics

(2011) Z.-Q. Ma et al.   BIOINFORMATICS

SYK inhibition and response prediction in diffuse large B-cell lymphoma

(2011) S. Cheng et al.   BLOOD

Strategies for aggregating gene expression data: The collapseRows R function

(2011) Jeremy A Miller et al.   BMC BIOINFORMATICS

Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung

(2011) Kate D. Sutherland et al.   CANCER CELL

Co-expression module analysis reveals biological processes, genomic gain, and regulatory mechanisms associated with breast cancer progression

(2010) Zhiao Shi et al.   BMC Systems Biology

Fyn

(2010) Yoshihito D. Saito et al.   CANCER

Spleen tyrosine kinases: biology, therapeutic targets and drugs

(2010) Mauro Riccaboni et al.   DRUG DISCOVERY TODAY

Comparative Shotgun Proteomics Using Spectral Count Data and Quasi-Likelihood Modeling

(2010) Ming Li et al.   JOURNAL OF PROTEOME RESEARCH

DNA copy number aberrations in small-cell lung cancer reveal activation of the focal adhesion pathway

(2010) S Ocak et al.   ONCOGENE

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

(2009) J. W. Friedberg et al.   BLOOD

Proteomic and Genetic Approaches Identify Syk as an AML Target

(2009) Cynthia K. Hahn et al.   CANCER CELL

Fyn and Src Are Effectors of Oncogenic Epidermal Growth Factor Receptor Signaling in Glioblastoma Patients

(2009) K. V. Lu et al.   CANCER RESEARCH

A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro

(2009) V. C. Daniel et al.   CANCER RESEARCH

Spleen Tyrosine Kinase Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

(2009) Maike Buchner et al.   CANCER RESEARCH

The Lymphoma-associated Fusion Tyrosine Kinase ITK-SYK Requires Pleckstrin Homology Domain-mediated Membrane Localization for Activation and Cellular Transformation

(2009) Sue Rigby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IDPicker 2.0: Improved Protein Assembly with High Discrimination Peptide Identification Filtering

(2009) Ze-Qiang Ma et al.   JOURNAL OF PROTEOME RESEARCH

Equivalence of Protein Inventories Obtained from Formalin-fixed Paraffin-embedded and Frozen Tissue in Multidimensional Liquid Chromatography-Tandem Mass Spectrometry Shotgun Proteomic Analysis

(2009) Robert W. Sprung et al.   MOLECULAR & CELLULAR PROTEOMICS

FYNis overexpressed in human prostate cancer

(2008) Edwin M. Posadas et al.   BJU INTERNATIONAL

BCR-ABL1 mediates up-regulation of Fyn in chronic myelogenous leukemia

(2008) K. Ban et al.   BLOOD

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Genetic changes in small cell lung carcinoma

(2008) Edurne Arriola et al.   Clinical & Translational Oncology

Evaluation of Strong Cation Exchange versus Isoelectric Focusing of Peptides for Multidimensional Liquid Chromatography-Tandem Mass Spectrometry

(2008) Robbert J. C. Slebos et al.   JOURNAL OF PROTEOME RESEARCH

Gene expression profiling for molecular distinction and characterization of laser captured primary lung cancers

(2008) Astrid Rohrbeck et al.   Journal of Translational Medicine

DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers

(2008) W W Lockwood et al.   ONCOGENE