Systems biology applied to vaccine and immunotherapy development

A novel parametric approach to mine gene regulatory relationship from microarray datasets

(2011) Wanlin Liu et al.   BMC BIOINFORMATICS

Monocyte-derived DC maturation strategies and related pathways: a transcriptional view

(2011) Luciano Castiello et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Bioinformatics challenges for genome-wide association studies

(2010) J. H. Moore et al.   BIOINFORMATICS

Correlates of Protection Induced by Vaccination

(2010) S. A. Plotkin   Clinical and Vaccine Immunology

Systems Vaccinology

(2010) Bali Pulendran et al.   IMMUNITY

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

Immunogenomics and systems biology of vaccines

(2010) Luigi Buonaguro et al.   IMMUNOLOGICAL REVIEWS

Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

(2010) Adam R. Hersperger et al.   PLoS Pathogens

Perforin and IL-2 Upregulation Define Qualitative Differences among Highly Functional Virus-Specific Human CD8+ T Cells

(2010) George Makedonas et al.   PLoS Pathogens

Harnessing Human Dendritic Cell Subsets to Design Novel Vaccines

(2009) Jacques Banchereau et al.   Annals of the New York Academy of Sciences

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

(2009) H. Harlin et al.   CANCER RESEARCH

Vaccines: the Fourth Century

(2009) S. A. Plotkin   Clinical and Vaccine Immunology

DNA vaccine therapy for chronic hepatitis C virus (HCV) infection: immune control of a moving target

(2009) Matti Sällberg et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Molecular immune signatures of HIV-1 vaccines in human PBMCs

(2009) Alessandro Monaco et al.   FEBS LETTERS

Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes

(2009) Inna G. Ovsyannikova et al.   HUMAN GENETICS

B Cell Receptor and BAFF Receptor Signaling Regulation of B Cell Homeostasis

(2009) W. N. Khan   JOURNAL OF IMMUNOLOGY

Absence of Mature Peripheral B Cell Populations in Mice with Concomitant Defects in B Cell Receptor and BAFF-R Signaling

(2009) K. L. Hoek et al.   JOURNAL OF IMMUNOLOGY

The Yellow Fever Virus Vaccine Induces a Broad and Polyfunctional Human Memory CD8+ T Cell Response

(2009) R. S. Akondy et al.   JOURNAL OF IMMUNOLOGY

Varicella‐Zoster Virus–Specific Immune Responses to Herpes Zoster in Elderly Participants in a Trial of a Clinically Effective Zoster Vaccine

(2009) Adriana Weinberg et al.   JOURNAL OF INFECTIOUS DISEASES

T-Cell Vaccine Strategies for Human Immunodeficiency Virus, the Virus with a Thousand Faces

(2009) B. T. Korber et al.   JOURNAL OF VIROLOGY

Host responses from innate to adaptive immunity after vaccination: Molecular and cellular events

(2009) Sang-Moo Kang et al.   MOLECULES AND CELLS

Viruses as vaccine vectors for infectious diseases and cancer

(2009) Simon J. Draper et al.   NATURE REVIEWS MICROBIOLOGY

Application of pharmacogenomics to vaccines

(2009) Gregory A Poland et al.   PHARMACOGENOMICS

The Heterogeneous Allelic Repertoire of Human Toll-Like Receptor (TLR) Genes

(2009) Philippe Georgel et al.   PLoS One

Does our Current Understanding of Immune Tolerance, Autoimmunity, and Immunosuppressive Mechanisms Facilitate the Design of Efficient Cancer Vaccines?

(2009) M. Sioud   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Enabling a systems biology approach to immunology: focus on innate immunity

(2009) Jennifer L. Gardy et al.   TRENDS IN IMMUNOLOGY

Polymorphisms of cytokine and innate immunity genes and GVHD

(2008) A.M. Dickinson et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Gene expression profile of peripheral blood mononuclear cells in response to HIV-VLPs stimulation

(2008) Luigi Buonaguro et al.   BMC BIOINFORMATICS

The Innate Immune Database (IIDB)

(2008) Martin Korb et al.   BMC IMMUNOLOGY

Innate signaling by the C-type lectin DC-SIGN dictates immune responses

(2008) Jeroen den Dunnen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant

(2008) C. R. Casella et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination

(2008) D M Reif et al.   GENES AND IMMUNITY

Bottom Up: A Modular View of Immunology

(2008) Ena Wang et al.   IMMUNITY

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

Antigen-Presentation Properties of Plasmacytoid Dendritic Cells

(2008) José A. Villadangos et al.   IMMUNITY

Mechanisms and Consequences of Dendritic Cell Migration

(2008) David Alvarez et al.   IMMUNITY

Human Effector and Memory CD8+ T Cell Responses to Smallpox and Yellow Fever Vaccines

(2008) Joseph D. Miller et al.   IMMUNITY

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY

Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures

(2008) Marie-Caroline Dieu-Nosjean et al.   JOURNAL OF CLINICAL ONCOLOGY

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

(2008) Denis Gaucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vitamin D Receptor Gene Haplotypes and Susceptibility to HIV‐1 Infection in Injection Drug Users

(2008) Manuel Sánchez de la Torre et al.   JOURNAL OF INFECTIOUS DISEASES

Th2 Polarization in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus (HIV)-Infected Subjects, as Activated by HIV Virus-Like Particles

(2008) L. Buonaguro et al.   JOURNAL OF VIROLOGY

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Association of Interacting Genes in the Toll-Like Receptor Signaling Pathway and the Antibody Response to Pertussis Vaccination

(2008) Tjeerd G. Kimman et al.   PLoS One

Distinct TLR- and NLR-Mediated Transcriptional Responses to an Intracellular Pathogen

(2008) Jess H. Leber et al.   PLoS Pathogens

The Effect of Trim5 Polymorphisms on the Clinical Course of HIV-1 Infection

(2008) Daniëlle van Manen et al.   PLoS Pathogens

The immunologic constant of rejection

(2008) Ena Wang et al.   TRENDS IN IMMUNOLOGY

New horizons in adjuvants for vaccine development

(2008) Steven G. Reed et al.   TRENDS IN IMMUNOLOGY

Engagement of TLR signaling as adjuvant: Towards smarter vaccine and beyond

(2008) Amit Lahiri et al.   VACCINE

Associations between SNPs in toll-like receptors and related intracellular signaling molecules and immune responses to measles vaccine: Preliminary results

(2008) Neelam Dhiman et al.   VACCINE

Virus-specific intestinal IFN-γ producing T cell responses induced by human rotavirus infection and vaccines are correlated with protection against rotavirus diarrhea in gnotobiotic pigs

(2008) Lijuan Yuan et al.   VACCINE