Article
Immunology
Mei Zhang, Xiaoxia Zhu, Jing Wu, Zhengjing Huang, Zhenping Zhao, Xiao Zhang, Yu Xue, Weiguo Wan, Chun Li, Wenrong Zhang, Linhong Wang, Maigeng Zhou, Hejian Zou, Limin Wang
Summary: The prevalence of hyperuricemia among Chinese adults in 2018-19 was 14.0%, with significant escalation observed between 2015-16 and 2018-19. Hyperuricemia was more common in men, but the prevalence also increased in women. Risk factors for hyperuricemia included urban culture, geographic region, ethnic descent, education level, alcohol consumption, dietary habits, physical activity, obesity, and certain chronic diseases.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Nutrition & Dietetics
Ruoyu Gou, Jian Qin, Weiyi Pang, Jiansheng Cai, Tingyu Luo, Kailian He, Song Xiao, Xu Tang, Zhiyong Zhang, You Li
Summary: The objective of this study was to investigate the relationship between dietary patterns and cognitive function in older adults. Four major dietary patterns were identified, and the vegetable and mushroom dietary pattern was found to be a protective factor for cognitive function. Therefore, increasing the intake of vegetables and mushrooms is recommended to prevent and mitigate cognitive decline.
FRONTIERS IN NUTRITION
(2023)
Article
Clinical Neurology
Shunli Jiang, Xinyong Zhou, Yaru Xu, Habib Ullah, Xinpeng Niu, Chen Feng, Qin Gao
Summary: Recent studies show inconsistent associations between manganese (Mn) levels and depression prevalence. This study aimed to evaluate the relationship between blood Mn concentrations and the risk of depression in US adults, finding that elevated blood Mn concentrations were associated with decreased depression risk in females and other specific subgroups.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Medicine, General & Internal
Md Belal Hossain, Jahidur Rahman Khan, Rajat Das Gupta
Summary: The study found a significant association between overweight/obesity and diabetes among Bangladeshi adults, with hypertension mediating this relationship. 18.64% of the effect of overweight/obesity on diabetes was mediated through hypertension, with a higher mediation effect observed among adults from non-poor households and both rural and urban areas.
Article
Nutrition & Dietetics
Rebecca Lindberg, Sarah A. McNaughton, Gavin Abbott, Christina M. Pollard, Amy L. Yaroch, Katherine M. Livingstone
Summary: This study investigated whether the diet quality of Australian adults differed based on their household food security status. Adults from food-insecure households had lower diet quality, consuming more carbohydrates and total sugar, and less protein, mono-unsaturated fats, and fiber, compared to food-secure adults.
Article
Clinical Neurology
Long Li, Guangzhao Jin, Yalong Guo, Yiyang Zhang, Rize Jing
Summary: This study examines the associations between various aspects of the digital divide, including Internet access, support, usage divides, and depressive symptoms among older adults in China. The findings suggest that access to Internet devices, support from family, and using the Internet for communication, entertainment, or as instruments are significantly associated with lower levels of depressive symptoms. The study also finds that the associations between the digital divide and depressive symptoms vary based on rural/urban status, with stronger associations observed among rural older adults.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Medicine, General & Internal
Abu Abdullah Mohammad Hanif, Abu Ahmed Shamim, Md Mokbul Hossain, Mehedi Hasan, Md Showkat Ali Khan, Moyazzam Hossaine, Mohammad Aman Ullah, Samir Kanti Sarker, S. M. Mustafizur Rahman, Dipak K. Mitra, Malay Kanti Mridha
Summary: In Bangladesh, half of the elderly population had hypertension, with a higher prevalence in females. In both genders, older age (>=70 years), insufficient physical activity, higher waist circumference, and self-reported diabetes were associated with higher odds of hypertension. Males living in slums had decreased odds of hypertension, while those with education >10 years had increased odds.
Article
Health Care Sciences & Services
Fahad Alamri, Yousef Alsofayan, Yazed AlRuthia, Ahmed Alahmari, Yasir Almuzaini, Fouad Abo Gazalah, Faten Alradini, Tareef Alaama, Anas Khan
Summary: Older COVID-19 patients aged 65 years and above, with multiple comorbidities, diabetes, hypertension, chronic kidney disease, and a history of hospital admission within the preceding year, are at a higher risk of hospitalization. On the other hand, being male and living with healthcare workers may lower the risk of hospitalization.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2021)
Article
Medicine, General & Internal
Israel Terungwa Agaku, Catherine O. Egbe, Olalekan A. Ayo-Yusuf
Summary: A study in South Africa highlighted the importance of investigating the exposure to e-cigarette advertising to inform public health programs and policies. Findings showed that younger individuals had higher exposure to e-cigarette advertisements and tended to believe that advertising could influence adolescent smoking behavior.
Article
Nutrition & Dietetics
Zhuo Wang, Tengfei Lin, Yaping Wei, Yun Song, Lishun Liu, Ziyi Zhou, Xiao Huang, Ping Chen, Chengzhang Liu, Youbao Li, Binyan Wang, Jianping Li, Yan Zhang, Yong Huo, Hao Zhang, Xiping Xu, Xianhui Qin, Huiyuan Guo
Summary: This study investigated the plasma selenium status of middle-aged to elderly adults with hypertension from 14 provinces in China and found relatively low plasma selenium concentrations. The results showed significant associations between plasma selenium status and geographic, demographic, and lifestyle characteristics, as well as blood pressure.
FRONTIERS IN NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Xinyao Liu, Guolin Dai, Qile He, Hao Ma, Hongpu Hu
Summary: This study aimed to investigate the association between the frailty index and cardiovascular disease (CVD) in middle-aged and older Chinese adults. Cross-sectional and cohort analyses were conducted using nationally representative data. The findings showed a significant association between frailty index and CVD, independent of age and other CVD risk factors.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2022)
Article
Nutrition & Dietetics
Varun Vohra, Evelyn M. Leland, Rodney J. Schlosser, Vidyulata Kamath, Nicholas R. Rowan
Summary: The study shows that dietary patterns high in protein/selenium and beta-carotene/vitamin A are associated with lower frailty prevalence in adults with olfactory dysfunction. These findings suggest that dietary patterns are uniquely associated with frailty in older adults with olfactory dysfunction.
Article
Public, Environmental & Occupational Health
Dongfeng Tang, Yiheng Zhou, Chengxu Long, Shangfeng Tang
Summary: This study investigated the association between midday napping and hypertension, and found a positive correlation between the two. BMI was found to have a partial mediation effect in this association.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2022)
Article
Medicine, General & Internal
Supa Pengpid, Karl Peltzer
Summary: Nearly 1 in 10 women and 1 in 20 men aged 18-69 years in Malawi had self-reported ischaemic heart disease and/or stroke. Factors associated with IHD and/or stroke included older age (50-69 years), female sex, speaking Chewa or English, suicidal ideation, plan and/or attempt, sedentary behavior, as well as non-paid or unemployed status, urban residence, overweight, obesity, and hypertension. These findings suggest potential targets for population health interventions.
Article
Environmental Sciences
Tingxin Li, Xiaoyue Tang, Yuping Liu, Yun Li, Baoming He
Summary: This study investigated the prevalence of Metabolic Syndrome (MetS) among Jiarong Tibetans in Aba Plateau, identified three major dietary patterns (traditional Tibetan, urbanized, and healthy), and found a significant association between the healthy dietary pattern and a lower risk of MetS. No significant statistical association was found between the risk of MetS and the traditional Tibetan and urbanized diet patterns.
ENVIRONMENTAL RESEARCH
(2021)
Article
Gastroenterology & Hepatology
Long H. Nguyen, Wenjie Ma, Dong D. Wang, Yin Cao, Himel Mallick, Teklu K. Gerbaba, Jason Lloyd-Price, Galeb Abu-Ali, A. Brantley Hall, Daniel Sikavi, David A. Drew, Raaj S. Mehta, Cesar Arze, Amit D. Joshi, Yan Yan, Tobyn Branck, Casey DuLong, Kerry L. Ivey, Shuji Ogino, Eric B. Rimm, Mingyang Song, Wendy S. Garrett, Jacques Izard, Curtis Huttenhower, Andrew T. Chan
Article
Medicine, General & Internal
Yanping Li, Josje Schoufour, Dong D. Wang, Klodian Dhana, An Pan, Xiaoran Liu, Mingyang Song, Gang Liu, Hyun Joon Shin, Qi Sun, Laila Al-Shaar, Molin Wang, Eric B. Rimm, Ellen Hertzmark, Meir J. Stampfer, Walter C. Willett, Oscar H. Franco, Frank B. Hu
BMJ-BRITISH MEDICAL JOURNAL
(2020)
Article
Food Science & Technology
Pablo Hernandez-Alonso, Nerea Becerra-Tomas, Christopher Papandreou, Monica Bullo, Marta Guasch-Ferre, Estefania Toledo, Miguel Ruiz-Canela, Clary B. Clish, Dolores Corella, Courtney Dennis, Amy Deik, Dong D. Wang, Cristina Razquin, Jean-Philippe Drouin-Chartier, Ramon Estruch, Emilio Ros, Montserrat Fito, Fernando Aros, Miquel Fiol, Lluis Serra-Majem, Liming Liang, Miguel A. Martinez-Gonzalez, Frank B. Hu, Jordi Salas-Salvado
MOLECULAR NUTRITION & FOOD RESEARCH
(2020)
Article
Medicine, General & Internal
Zhilei Shan, Yanping Li, Megu Y. Baden, Shilpa N. Bhupathiraju, Dong D. Wang, Qi Sun, Kathryn M. Rexrode, Eric B. Rimm, Lu Qi, Walter C. Willett, JoAnn E. Manson, Qibin Qi, Frank B. Hu
JAMA INTERNAL MEDICINE
(2020)
Article
Gastroenterology & Hepatology
Ehud Rinott, Ilan Youngster, Anat Yaskolka Meir, Gal Tsaban, Hila Zelicha, Alon Kaplan, Dan Knights, Kieran Tuohy, Francesca Fava, Matthias Uwe Scholz, Oren Ziv, Elad Reuven, Amir Tirosh, Assaf Rudich, Matthias Blueher, Michael Stumvoll, Uta Ceglarek, Karine Clement, Omry Koren, Dong D. Wang, Frank B. Hu, Meir J. Stampfer, Iris Shai
Summary: This study evaluated the efficacy and safety of diet-modulated autologous fecal microbiota transplantation (aFMT) for treatment of weight regain after the weight-loss phase. The results showed that in the green-Mediterranean diet group, aFMT significantly reduced weight regain and waist circumference gain, improved insulin rebound, and induced significant changes in gut microbiome composition. The green-Mediterranean diet also preserved weight-loss-associated specific bacteria and microbial metabolic pathways after the aFMT procedure.
Article
Medicine, General & Internal
Laila Al-Shaar, Ambika Satija, Dong D. Wang, Eric B. Rimm, Stephanie A. Smith-Warner, Meir J. Stampfer, Frank B. Hu, Walter C. Willett
BMJ-BRITISH MEDICAL JOURNAL
(2020)
Article
Cardiac & Cardiovascular Systems
Dong D. Wang, Yanping Li, Shilpa N. Bhupathiraju, Bernard A. Rosner, Qi Sun, Edward L. Giovannucci, Eric B. Rimm, JoAnn E. Manson, Walter C. Willett, Meir J. Stampfer, Frank B. Hu
Summary: The study found that consuming approximately 5 servings of fruits and vegetables per day was associated with lower total mortality and mortality from cancer, cardiovascular disease, and respiratory disease. Higher intake beyond this level did not provide additional risk reduction.
Article
Biochemistry & Molecular Biology
Dong D. Wang, Long H. Nguyen, Yanping Li, Yan Yan, Wenjie Ma, Ehud Rinott, Kerry L. Ivey, Iris Shai, Walter C. Willett, Frank B. Hu, Eric B. Rimm, Meir J. Stampfer, Andrew T. Chan, Curtis Huttenhower
Summary: The study shows that a healthy Mediterranean-style diet is linked to specific functional and taxonomic components of the gut microbiome, and its protective effects on cardiometabolic health depend on microbial composition. In particular, the protective association between adherence to the Mediterranean diet and cardiometabolic disease risk is significantly stronger among participants with decreased abundance of Prevotella copri.
Article
Gastroenterology & Hepatology
Jun Li, Yanping Li, Kerry L. Ivey, Dong D. Wang, Jeremy E. Wilkinson, Adrian Franke, Kyu Ha Lee, Andrew Chan, Curtis Huttenhower, Frank B. Hu, Eric B. Rimm, Qi Sun
Summary: This study found that high intake of red meat and choline was significantly associated with TMAO concentrations, especially among participants identified as microbial TMAO-producers. Alistipes shahii strengthened the positive association between red meat intake and HbA1c levels. The results underscore the interaction between diet and gut microbiome in producing potentially bioactive metabolites that may modulate cardiometabolic health.
Article
Nutrition & Dietetics
Yanping Li, Dong D. Wang, Ambika Satija, Kerry L. Ivey, Jun Li, Jeremy E. Wilkinson, Ruifeng Li, Megu Baden, Andrew T. Chan, Curtis Huttenhower, Eric B. Rimm, Frank B. Hu, Qi Sun
Summary: The study found that older men adhering to a healthy plant-based diet were associated with specific microbial species and metabolic pathways, and their inverse association with human metabolic risk partially depended on microbial compositions.
JOURNAL OF NUTRITION
(2021)
Article
Genetics & Heredity
Wenjie Ma, Long H. Nguyen, Mingyang Song, Dong D. Wang, Eric A. Franzosa, Yin Cao, Amit Joshi, David A. Drew, Raaj Mehta, Kerry L. Ivey, Lisa L. Strate, Edward L. Giovannucci, Jacques Izard, Wendy Garrett, Eric B. Rimm, Curtis Huttenhower, Andrew T. Chan
Summary: A higher intake of dietary fiber is associated with a decreased risk of chronic inflammatory diseases by altering gut microbiome composition and mitigating systemic inflammation. Specific gut microbial configurations correspond with higher levels of C-reactive protein.
Article
Endocrinology & Metabolism
Danielle E. Haslam, Liming Liang, Dong D. Wang, Rachel S. Kelly, Clemens Wittenbecher, Cynthia M. Perez, Marijulie Martinez, Chih-Hao Lee, Clary B. Clish, David T. W. Wong, Laurence D. Parnell, Chao-Qiang Lai, Jose M. Ordovas, JoAnn E. Manson, Frank B. Hu, Meir J. Stampfer, Katherine L. Tucker, Kaumudi J. Joshipura, Shilpa N. Bhupathiraju
Summary: In this study, network analysis was used to identify clusters of coregulated metabolites associated with prevalent type 2 diabetes (T2D) among Puerto Rican adults. The results revealed several known and novel metabolite clusters that were significantly associated with T2D in the study cohorts. Meta-analysis showed consistent associations between specific metabolite clusters and prevalent T2D, highlighting the potential importance of these metabolic pathways in the development of the disease.
BMJ OPEN DIABETES RESEARCH & CARE
(2021)
Article
Endocrinology & Metabolism
Dong D. Wang, Qibin Qi, Zheng Wang, Mykhaylo Usyk, Daniela Sotres-Alvarez, Josiemer Mattei, Martha Tamez, Marc D. Gellman, Martha Daviglus, Frank B. Hu, Meir J. Stampfer, Curtis Huttenhower, Rob Knight, Robert D. Burk, Robert C. Kaplan
Summary: This study reveals that adherence to the Mediterranean diet can affect gut microbiome composition and functions. The association between the Mediterranean diet and diabetes prevalence varies depending on individual gut microbial composition.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Meeting Abstract
Cardiac & Cardiovascular Systems
Dong Wang, Qibin Qi, Zheng Wang, Mykhaylo Usyk, Daniela Sotres-Alvarez, Josiemer Mattei, Martha Tamez, Marc Gellman, Martha L. Daviglus, Frank B. Hu, Rob Knight, Robert Burk, Robert Kaplan
Article
Nutrition & Dietetics
Marta Guasch-Ferre, Jose L. Santos, Miguel A. Martinez-Gonzalez, Clary B. Clish, Cristina Razquin, Dong Wang, Liming Liang, Jun Li, Courtney Dennis, Dolores Corella, Carlos Munoz-Bravo, Dora Romaguera, Ramon Estruch, Jose Manuel Santos-Lozano, Olga Castaner, Angel Alonso-Gomez, Luis Serra-Majem, Emilio Ros, Silvia Canudas, Eva M. Asensio, Montserrat Fito, Kerry Pierce, J. Alfredo Martinez, Jordi Salas-Salvado, Estefania Toledo, Frank B. Hu, Miguel Ruiz-Canela
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2020)