Review
Microbiology
Antonio Desai, Stefano Aliberti, Francesco Amati, Anna Stainer, Antonio Voza
Summary: Community-acquired pneumonia (CAP) is a major cause of high mortality in pediatric and adult populations worldwide, with significant cardiovascular complications. This study provides an updated perspective on the pathophysiology, risk factors, outcomes, and treatments of cardiovascular events in CAP patients, highlighting the importance of stratification and preventive measures for at-risk patients.
Review
Medicine, General & Internal
Edinson Dante Meregildo-Rodriguez, Martha Genara Asmat-Rubio, Mayra Janett Rojas-Benites, Gustavo Adolfo Vasquez-Tirado
Summary: One-third of adult inpatients with community-acquired pneumonia (CAP) develop acute coronary syndrome (ACS), stroke, heart failure (HF), arrhythmias, or die. The evidence linking CAP to cardiovascular disease (CVD) events is contradictory. We aimed to systematically review the role of CAP as a CVD risk factor.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Geriatrics & Gerontology
Yu Kang, Xiang-Yang Fang, Dong Wang, Xiao-Juan Wang
Summary: The incidence of AMI during CAP hospitalization in geriatric patients is notable and has an impact on in-hospital mortality. Respiratory failure, preexisting coronary artery disease, diabetes, and BUN are associated with the occurrence of AMI in older patients after hospitalization with CAP. Special attention should be paid to older patients with risk factors for AMI.
Article
Microbiology
Thomas Chandler, Stephen Furmanek, Ruth Carrico, Dawn Balcom, Forest Arnold, Julio Ramirez
Summary: This study analyzed the effectiveness of the 23-valent pneumococcal polysaccharide vaccine (PPSV23) for preventing hospitalization due to serotype-specific community-acquired pneumonia (CAP). The results showed that PPSV23 did not offer protection against CAP hospitalization caused by the vaccine-contained serotypes. This study highlights the importance of developing more effective vaccines for the prevention of hospitalization due to S. pneumoniae CAP.
Article
Immunology
Joseph A. Lewnard, Noga Givon-Lavi, Ron Dagan
Summary: The study analyzed the effectiveness of PCV in protecting children against pneumonia caused by different vaccine-targeted pneumococcal serotypes in southern Israel. The results showed that PCV could effectively reduce carriage of vaccine-serotype pneumococci and decrease the risk of disease progression.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Immunology
Nobuhiro Narii, Tetsuhisa Kitamura, Sho Komukai, Ling Zha, Masayo Komatsu, Fumiko Murata, Megumi Maeda, Kosuke Kiyohara, Tomotaka Sobue, Haruhisa Fukuda
Summary: The study aimed to investigate the protective effect of the 23-valent pneumococcal polysaccharide vaccine (PPSV23) on cardiovascular events in adults aged >= 65 years. The results showed that individuals who were PPSV23 vaccinated had significantly lower odds of acute myocardial infarction (AMI) or stroke events compared to unvaccinated individuals. More recent PPSV23 vaccination was associated with even lower odds ratios for AMI or stroke.
Article
Cardiac & Cardiovascular Systems
Jennifer Ma, Miguel Mena, Roshni A. Mandania, Arjab Ghosh, Christopher Dodoo, Alok K. Dwivedi, Debabrata Mukherjee
Summary: The study findings indicate that receiving the influenza vaccine, PPV, and the combined vaccination of pneumococcal and influenza vaccines can significantly reduce the risk of mortality. These data confirm the safety of administering these vaccines in hospitals and support the benefits of combined vaccination in reducing cardiovascular events.
Article
Medicine, General & Internal
Hakjun Hyun, A-Yeung Jang, Jin Woong Suh, In-Gyu Bae, Won Suk Choi, Yu Bin Seo, Jacob Lee, Jin Gu Yoon, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim, Min Ja Kim, Joon Young Song
Summary: The serotype distribution of pneumococcus in South Korea is evolving, which hinders vaccine rollout. Despite vaccination efforts, serotypes 3 and 19A remain the most common in pneumococcal pneumonia cases in South Korea.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Immunology
Jung Yeon Heo, Yu Bin Seo, Won Suk Choi, Eun Jin Kim, Hye Won Jeong, Jacob Lee, Jin Gu Yoon, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim, Joon Young Song
Summary: The effectiveness of pneumococcal vaccines against pneumococcal pneumonia is low in the elderly. However, sequential PCV13/PPSV23 vaccination shows the highest effectiveness in the younger subgroup.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Immunology
David Aguilera-Alonso, Silke Kirchschlager Nieto, Maria Fatima Ara Montojo, Francisco Jose Sanz Santaeufemia, Jesus Saavedra-Lozano, Beatriz Soto, Maria Belen Caminoa, Arantxa Berzosa, Luis Prieto Tato, Emilia Cercenado, Alfredo Tagarro, David Molina Arana, Mercedes Alonso Sanz, Maria Pilar Romero Gomez, Fernando Chaves Sanchez, Fernando Baquero-Artigao
Summary: The incidence of Staphylococcus aureus community-acquired pneumonia (CAP) remained stable in hospitalized children with high pneumococcal vaccination coverage, while the prevalence of pneumococcal CAP decreased and Streptococcus pyogenes CAP increased. Patients with S. aureus CAP had a high frequency of severe outcomes but a lower risk of pulmonary complications compared to patients with S. pneumoniae.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2022)
Article
Immunology
Ching-Fen Shen, Ju-Ling Chen, Chien-Chou Su, Wen-Liang Lin, Min-Ling Hsieh, Ching-Chun Liu, Ching-Lan Cheng
Summary: The implementation of PCV13 in Taiwan has significantly reduced hospitalizations for P-CAP, especially in children and adults, and has markedly decreased ICU rates and severe pneumonia cases.
Article
Microbiology
Christian Theilacker, Mark A. Fletcher, Luis Jodar, Bradford D. Gessner
Summary: This article reviews the Community-Acquired Pneumonia immunization Trial in Adults (CAPiTA) and its extended studies, highlighting the efficacy of the 13-valent pneumococcal conjugate vaccine (PCV13) in preventing pneumonia and invasive pneumococcal disease in older adults. It provides valuable insights for the assessment of adult pneumococcal vaccination.
Article
Immunology
Tao Zhang, Jun Zhang, Xuejun Shao, Shuang Feng, Xinxin Xu, Benfeng Zheng, Changpeng Liu, Zirui Dai, Qin Jiang, Bradford D. Gessner, Qinghui Chen, Jun Zhu, Lin Luan, Jianmei Tian, Genming Zhao
Summary: The study showed that PCV13 was effective in protecting against VT-CAP and clinical CAP in children in Suzhou, China, with significant reductions in incidence rates.
Article
Infectious Diseases
Aline Wolfensberger, Lauren Clack, Stefanie von Felten, Mirjam Faes Hesse, Dirk Saleschus, Marie-Theres Meier, Katharina Kusejko, Roger Kouyos, Leonhard Held, Hugo Sax
Summary: This study aimed to test a prevention intervention for non-ventilator-associated hospital-acquired pneumonia and a multifaceted implementation strategy. The results showed that implementing the prevention intervention significantly reduced the incidence rate of nvHAP.
LANCET INFECTIOUS DISEASES
(2023)
Letter
Medicine, General & Internal
Jan O. Friedrich, Elisa Gouvea Bogossian
Summary: In a trial evaluating the efficacy of hydrocortisone in treating community-acquired pneumonia, researchers found a nearly 50% lower 28-day mortality rate in the hydrocortisone group compared to the placebo group. They also observed a higher incidence of septic shock in the placebo group. The trial did not allow the use of open-label glucocorticoids, which may have contributed to the higher mortality rate in the placebo group.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Clinical Neurology
E. Satue, A. Vila-Corcoles, O. Ochoa-Gondar, C. de Diego, M. J. Forcadell, T. Rodriguez-Blanco, L. Barnes, M. Jariod
ACTA NEUROLOGICA SCANDINAVICA
(2016)
Article
Medicine, General & Internal
Angel Vila-Corcoles, Xabier Ansa, Olga Ochoa-Gondar, Eva Satue, Cinta de Diego, Teresa Rodriguez-Blanco
Article
Biotechnology & Applied Microbiology
Angel Vila-Corcoles, Olga Ochoa-Gondar, Imma Hospital, Cinta de Diego, Eva Satue, Jordi Blade, Xabier Ansa, Jorge A. Guzman, Elisabet Salsench, Francisca Ramos
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2016)
Article
Infectious Diseases
Angel Vila-Corcoles, Olga Ochoa-Gondar, Cinta de Diego, Eva Satue, Maria Aragon, Angel Vila-Rovira, Frederic Gomez-Bertomeu, Ramon Magarolas, Enric Figuerola-Massana, Xavier Raga, Mar O. Perez, Frederic Ballester
BMC INFECTIOUS DISEASES
(2018)
Article
Cardiac & Cardiovascular Systems
M. Jose Forcadell, Angel Vila-Corcoles, Cinta de Diego, Olga Ochoa-Gondar, Eva Satue
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2018)
Article
Infectious Diseases
Angel Vila-Corcoles, Olga Ochoa-Gondar, Cinta de Diego, Eva Satue, Angel Vila-Rovira, Maria Aragon
Article
Immunology
Angel Vila-Corcoles, Immaculada Hospital, Olga Ochoa-Gondar, Eva Satue, Cinta de Diego, Angel Vila-Rovira, Frederic Gomez-Bertomeu, Xavier Raga, Maria Aragon
Article
Respiratory System
A. Vila-Corcoles, O. Ochoa-Gondar, A. Vila-Rovira, M. Aragon, L. Esteban-Julvez, N. Chamorro, I Hospital, E. Satue, J. Blade, C. de Diego, F. Gomez-Bertomeu, X. Raga
Article
Peripheral Vascular Disease
Angel Vila-Corcoles, Eva Satue-Gracia, Olga Ochoa-Gondar, Cristina Torrente-Fraga, Frederic Gomez-Bertomeu, Angel Vila-Rovira, Imma Hospital-Guardiola, Cinta de Diego-Cabanes, Ferran Bejarano-Romero, Dolors Rovira-Veciana, Josep Basora-Gallisa
JOURNAL OF CLINICAL HYPERTENSION
(2020)
Article
Medicine, General & Internal
Angel Vila-Corcoles, Olga Ochoa-Gondar, Eva M. Satue-Gracia, Cristina Torrente-Fraga, Frederic Gomez-Bertomeu, Angel Vila-Rovira, Immaculada Hospital-Guardiola, Cinta de Diego-Cabanes, Ferran Bejarano-Romero, Josep Basora-Gallisa
Article
Public, Environmental & Occupational Health
Angel Vila-Corcoles, Eva Satue-Gracia, Angel Vila-Rovira, Cinta de Diego-Cabanes, Maria Jose Forcadell-Peris, Immaculada Hospital-Guardiola, Olga Ochoa-Gondar, Josep Basora-Gallisa
Summary: The study found that COVID19-related deaths accounted for over 20% of all-cause mortality among middle-aged and older adults during the first wave of the pandemic, with about 10% of these deaths attributed to other concomitant causes. Significant predictors for COVID19-related mortality included age, sex, nursing-home residence, and number of pre-existing comorbidities.
Article
Public, Environmental & Occupational Health
O. Ochoa-Gondar, I. Hospital, A. Vila-Corcoles, M. Aragon, M. Jariod, C. de Diego, E. Satue
Article
Primary Health Care
Angel Vila-Corcoles, Olga Ochoa-Gondar
Article
Public, Environmental & Occupational Health
Angel Vila-Corcoles, Olga Ochoa-Gondar, Eva Satue, Marc Vila-Rovira, Manel Jariod
REVISTA ESPANOLA DE SALUD PUBLICA
(2017)