Human cellular restriction factors that target HIV-1 replication

Mechanisms employed by retroviruses to exploit host factors for translational control of a complicated proteome

(2012) Cheryl Bolinger et al.   Retrovirology

New Tricks for Animal MicroRNAs: Targeting of Amino Acid Coding Regions at Conserved and Nonconserved Sites

(2009) I. Rigoutsos   CANCER RESEARCH

X-Ray Structures of the Hexameric Building Block of the HIV Capsid

(2009) Owen Pornillos et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists

(2009) Fengwen Zhang et al.   Cell Host & Microbe

HIV-1 Antagonism of CD317 Is Species Specific and Involves Vpu-Mediated Proteasomal Degradation of the Restriction Factor

(2009) Christine Goffinet et al.   Cell Host & Microbe

Requirement for Sun1 in the expression of meiotic reproductive genes and piRNA

(2009) Y.-H. Chi et al.   DEVELOPMENT

Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G

(2009) Ayako Furukawa et al.   EMBO JOURNAL

The NS3 protein of rice hoja blanca virus complements the RNAi suppressor function of HIV-1 Tat

(2009) Esther Schnettler et al.   EMBO REPORTS

A Genome-wide Short Hairpin RNA Screening of Jurkat T-cells for Human Proteins Contributing to Productive HIV-1 Replication

(2009) Man Lung Yeung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential RNA silencing suppression activity of NS1 proteins from different influenza A virus strains

(2009) W. de Vries et al.   JOURNAL OF GENERAL VIROLOGY

An Extended Structure of the APOBEC3G Catalytic Domain Suggests a Unique Holoenzyme Model

(2009) Elena Harjes et al.   JOURNAL OF MOLECULAR BIOLOGY

An Invariant Surface Patch on the TRIM5  PRYSPRY Domain Is Required for Retroviral Restriction but Dispensable for Capsid Binding

(2009) S. Sebastian et al.   JOURNAL OF VIROLOGY

A Patch of Positively Charged Amino Acids Surrounding the Human Immunodeficiency Virus Type 1 Vif SLVx4Yx9Y Motif Influences Its Interaction with APOBEC3G

(2009) G. Chen et al.   JOURNAL OF VIROLOGY

Suppression of Tetherin-Restricting Activity upon Human Immunodeficiency Virus Type 1 Particle Release Correlates with Localization of Vpu in the trans-Golgi Network

(2009) M. Dube et al.   JOURNAL OF VIROLOGY

Truncation of TRIM5 in the Feliformia Explains the Absence of Retroviral Restriction in Cells of the Domestic Cat

(2009) W. A. McEwan et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Type 1 Suppresses RNA-Induced Gene Silencing in Mammalian Cells

(2009) Z. Wu et al.   JOURNAL OF VIROLOGY

Identification of a Novel WxSLVK Motif in the N Terminus of Human Immunodeficiency Virus and Simian Immunodeficiency Virus Vif That Is Critical for APOBEC3G and APOBEC3F Neutralization

(2009) Y. Dang et al.   JOURNAL OF VIROLOGY

The Transmembrane Domain of BST-2 Determines Its Sensitivity to Down-Modulation by Human Immunodeficiency Virus Type 1 Vpu

(2009) L. Rong et al.   JOURNAL OF VIROLOGY

Vpu Directs the Degradation of the Human Immunodeficiency Virus Restriction Factor BST-2/Tetherin via a  TrCP-Dependent Mechanism

(2009) J. L. Douglas et al.   JOURNAL OF VIROLOGY

Cellular MicroRNA and P Bodies Modulate Host-HIV-1 Interactions

(2009) Robin Nathans et al.   MOLECULAR CELL

A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

(2009) Sonia A Melo et al.   NATURE GENETICS

HIV-1 Tat RNA silencing suppressor activity is conserved across kingdoms and counteracts translational repression of HIV-1

(2009) S. Qian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vpu enhances HIV-1 virus release in the absence of Bst-2 cell surface down-modulation and intracellular depletion

(2009) Eri Miyagi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein

(2009) Rachel L. Kaletsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative study on the effect of human BST-2/Tetherin on HIV-1 release in cells of various species

(2009) Kei Sato et al.   Retrovirology

APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA

(2009) Rebecca A Russell et al.   Retrovirology

HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression

(2009) Zachary Klase et al.   Retrovirology

Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA

(2009) Yeshitila N Friew et al.   Retrovirology

Suppression of HIV-1 replication by microRNA effectors

(2009) Christine Chable-Bessia et al.   Retrovirology

An expanded clade of rodent Trim5 genes

(2009) Semih U. Tareen et al.   VIROLOGY

Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent

(2009) Edward P. Browne et al.   VIROLOGY

Reassessing the Role of APOBEC3G in Human Immunodeficiency Virus Type 1 Infection of Quiescent CD4+ T-Cells

(2009) Masakazu Kamata et al.   PLoS Pathogens

Mutation of a Single Residue Renders Human Tetherin Resistant to HIV-1 Vpu-Mediated Depletion

(2009) Ravindra K. Gupta et al.   PLoS Pathogens

Are Viruses Inhibited by APOBEC3 Molecules from Their Host Species?

(2009) Susan R. Ross   PLoS Pathogens

Deaminase-Independent Inhibition of Parvoviruses by the APOBEC3A Cytidine Deaminase

(2009) Iñigo Narvaiza et al.   PLoS Pathogens

HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent Degradation

(2009) Bastien Mangeat et al.   PLoS Pathogens

RNAi Targeting of West Nile Virus in Mosquito Midguts Promotes Virus Diversification

(2009) Doug E. Brackney et al.   PLoS Pathogens

RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1

(2009) Hendrik Huthoff et al.   PLoS Pathogens

Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain Variants

(2009) Matthew W. McNatt et al.   PLoS Pathogens

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

(2009) Richard S. Mitchell et al.   PLoS Pathogens

Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2

(2009) Bin Jia et al.   PLoS Pathogens

The roles of microRNAs in mammalian virus infection

(2008) R GRASSMANN et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Cellular microRNA expression correlates with susceptibility of monocytes/macrophages to HIV-1 infection

(2008) X. Wang et al.   BLOOD

25 years of HIV-1 research – progress and perspectives

(2008) Mark A Wainberg et al.   BMC Medicine

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

(2008) Renate König et al.   CELL

Genome-Scale RNAi Screen for Host Factors Required for HIV Replication

(2008) Honglin Zhou et al.   Cell Host & Microbe

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

Viral and Cellular MicroRNAs as Determinants of Viral Pathogenesis and Immunity

(2008) Eva Gottwein et al.   Cell Host & Microbe

Ubiquitination of E3 ubiquitin ligase TRIM5α and its potential role

(2008) Keiko Yamauchi et al.   FEBS Journal

Increased virus replication in mammalian cells by blocking intracellular innate defense responses

(2008) W de Vries et al.   GENE THERAPY

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

(2008) J. E. Babiarz et al.   GENES & DEVELOPMENT

The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus

(2008) Robert Flisiak et al.   HEPATOLOGY

Insights into cellular microRNAs and human immunodeficiency virus type 1 (HIV-1)

(2008) Ajit Kumar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Characterization of Conserved Motifs in HIV-1 Vif Required for APOBEC3G and APOBEC3F Interaction

(2008) Zhiwen He et al.   JOURNAL OF MOLECULAR BIOLOGY

Differential Sensitivity of "Old" versus "New" APOBEC3G to Human Immunodeficiency Virus Type 1 Vif

(2008) R. Goila-Gaur et al.   JOURNAL OF VIROLOGY

Regulation of APOBEC3 Proteins by a Novel YXXL Motif in Human Immunodeficiency Virus Type 1 Vif and Simian Immunodeficiency Virus SIVagm Vif

(2008) E. Pery et al.   JOURNAL OF VIROLOGY

The TRIM5  B-Box 2 Domain Promotes Cooperative Binding to the Retroviral Capsid by Mediating Higher-Order Self-Association

(2008) X. Li et al.   JOURNAL OF VIROLOGY

Distinct Domains within APOBEC3G and APOBEC3F Interact with Separate Regions of Human Immunodeficiency Virus Type 1 Vif

(2008) R. A. Russell et al.   JOURNAL OF VIROLOGY

Cyclophilin A-Dependent Restriction of Human Immunodeficiency Virus Type 1 Capsid Mutants for Infection of Nondividing Cells

(2008) M. Qi et al.   JOURNAL OF VIROLOGY

Biochemical Characterization of a Recombinant TRIM5  Protein That Restricts Human Immunodeficiency Virus Type 1 Replication

(2008) C. R. Langelier et al.   JOURNAL OF VIROLOGY

Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins

(2008) R. S. LaRue et al.   JOURNAL OF VIROLOGY

The DNA Deaminase Activity of Human APOBEC3G Is Required for Ty1, MusD, and Human Immunodeficiency Virus Type 1 Restriction

(2008) A. J. Schumacher et al.   JOURNAL OF VIROLOGY

Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin

(2008) N. Jouvenet et al.   JOURNAL OF VIROLOGY

Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications

(2008) Lauren G. Holden et al.   NATURE

Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G

(2008) Kuan-Ming Chen et al.   NATURE

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

(2008) Yvonne Tay et al.   NATURE

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

(2008) Toshiaki Watanabe et al.   NATURE

Identification of calcium-modulating cyclophilin ligand as a human host restriction to HIV-1 release overcome by Vpu

(2008) Vasundhara Varthakavi et al.   NATURE MEDICINE

Identification of functional microRNAs released through asymmetrical processing of HIV-1 TAR element

(2008) D. L. Ouellet et al.   NUCLEIC ACIDS RESEARCH

TRIMCyp expression in Old World primates Macaca nemestrina and Macaca fascicularis

(2008) G. Brennan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species

(2008) C. A. Virgen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Independent evolution of an antiviral TRIMCyp in rhesus macaques

(2008) S. J. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ESF-EMBO Symposium: Antiviral Applications of RNA Interference

(2008) Olivier ter Brake et al.   Retrovirology

APOBEC3G encapsidation into HIV-1 virions: which RNA is it?

(2008) Klaus Strebel et al.   Retrovirology

Integrase and integration: biochemical activities of HIV-1 integrase

(2008) Olivier Delelis et al.   Retrovirology

Common principles and intermediates of viral protein-mediated fusion: the HIV-1 paradigm

(2008) Gregory B Melikyan   Retrovirology

HIV-1 Vif, APOBEC, and Intrinsic Immunity

(2008) Ritu Goila-Gaur et al.   Retrovirology

MicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals

(2008) Laurent Houzet et al.   Retrovirology

Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication

(2008) Jasmine K Ahluwalia et al.   Retrovirology

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE

Determinants of cyclophilin A-dependent TRIM5α restriction against HIV-1

(2008) Tsai-Yu Lin et al.   VIROLOGY

HCV core protein interacts with Dicer to antagonize RNA silencing

(2008) Weixian Chen et al.   VIRUS RESEARCH

Evolution of a TRIM5-CypA Splice Isoform in Old World Monkeys

(2008) Ruchi M. Newman et al.   PLoS Pathogens

Function analysis of sequences in human APOBEC3G involved in Vif-mediated degradation

(2007) Li Zhang et al.   VIROLOGY