Granzyme B secretion by human memory CD4 T cells is less strictly regulated compared to memory CD8 T cells

HIV replication in conjunction with granzyme B production by CCR5+ memory CD4 T cells: Implications for bystander cell and tissue pathologies

(2014) Jacob Couturier et al.   VIROLOGY

Dasatinib promotes Th1-type responses in granzyme B expressing T-cells

(2014) Anna Kreutzman et al.   OncoImmunology

IL-21-stimulated human plasmacytoid dendritic cells secrete granzyme B, which impairs their capacity to induce T-cell proliferation

(2013) J. J. Karrich et al.   BLOOD

High Efficiency of Antiviral CD4+ Killer T Cells

(2013) Steven K. Hildemann et al.   PLoS One

Granzyme B- and Fas ligand-mediated cytotoxic function induced by mitogenic CD28 stimulation of human memory CD4+ T cells

(2012) Miguel A. Medina et al.   JOURNAL OF LEUKOCYTE BIOLOGY

poly(I:C) costimulation induces a stronger antiviral chemokine and granzyme B release in human CD4 T cells than CD28 costimulation

(2012) Tim Meyer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Multifunctional CD4 Cells Expressing Gamma Interferon and Perforin Mediate Protection against Lethal Influenza Virus Infection

(2012) D. M. Brown et al.   JOURNAL OF VIROLOGY

Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection

(2012) J Loebbermann et al.   Mucosal Immunology

Perforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection

(2012) M. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ELISPOT Assay for Monitoring Cytotoxic T Lymphocytes (CTL) Activity in Cancer Vaccine Clinical Trials

(2012) Anatoli M. Malyguine et al.   Cells

Cytomegalovirus (CMV)-Specific Perforin and Granzyme B ELISPOT Assays Detect Reactivation of CMV Infection in Inflammatory Bowel Disease

(2012) Tobias M. Nowacki et al.   Cells

Protection from Endogenous Perforin: Glycans and the C Terminus Regulate Exocytic Trafficking in Cytotoxic Lymphocytes

(2011) Amelia J. Brennan et al.   IMMUNITY

Cytolytic CD4 cells: Direct mediators in infectious disease and malignancy

(2010) Deborah M. Brown   CELLULAR IMMUNOLOGY

Tumor-reactive CD4+T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

(2010) Sergio A. Quezada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cytokine Secretion Is Distinct from Secretion of Cytotoxic Granules in NK Cells

(2010) E. Reefman et al.   JOURNAL OF IMMUNOLOGY

Pathways for Cytokine Secretion

(2010) Amanda C. Stanley et al.   PHYSIOLOGY

Functional and Pathogenic Differences of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

(2010) Helena S. Domingues et al.   PLoS One

Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion

(2009) B. Jahrsdorfer et al.   BLOOD

Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway

(2009) Olga V Efimova et al.   BMC IMMUNOLOGY

Differential Expression of Granzyme B and C in Murine Cytotoxic Lymphocytes

(2009) Sheng F. Cai et al.   JOURNAL OF IMMUNOLOGY

Human B Cells Secrete Granzyme B When Recognizing Viral Antigens in the Context of the Acute Phase Cytokine IL-21

(2009) M. Hagn et al.   JOURNAL OF IMMUNOLOGY