Genetic dissection of blood lipid traits by integrating genome-wide association study and gene expression profiling in a porcine model

Finding genes and variants for lipid levels after genome-wide association analysis

(2012) Cristen J. Willer et al.   CURRENT OPINION IN LIPIDOLOGY

Rapid variance components–based method for whole-genome association analysis

(2012) Gulnara R Svishcheva et al.   NATURE GENETICS

A Genome-Wide Investigation of Expression Characteristics of Natural Antisense Transcripts in Liver and Muscle Samples of Pigs

(2012) Congying Chen et al.   PLoS One

Functional genomics and genetical genomics approaches towards elucidating networks of genes affecting meat performance in pigs

(2011) K. Wimmers et al.   Briefings in Functional Genomics

Heterozygosity for a Loss-of-Function Mutation in GALNT2 Improves Plasma Triglyceride Clearance in Man

(2011) Adriaan G. Holleboom et al.   Cell Metabolism

Regulator of G Protein Signaling (RGS16) Inhibits Hepatic Fatty Acid Oxidation in a Carbohydrate Response Element-binding Protein (ChREBP)-dependent Manner

(2011) Victor Pashkov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrating expression profiling and whole-genome association for dissection of fat traits in a porcine model

(2011) S. Ponsuksili et al.   JOURNAL OF LIPID RESEARCH

SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome

(2011) Matthew D. Hirschey et al.   MOLECULAR CELL

A Deficiency of Ceramide Biosynthesis Causes Cerebellar Purkinje Cell Neurodegeneration and Lipofuscin Accumulation

(2011) Lihong Zhao et al.   PLoS Genetics

Trib1 is a lipid- and myocardial infarction–associated gene that regulates hepatic lipogenesis and VLDL production in mice

(2010) Ralph Burkhardt et al.   JOURNAL OF CLINICAL INVESTIGATION

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

(2009) Philippa J. Talmud et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Nucleotide Sequence and Association Analysis of Pig Apolipoprotein-B and LDL-Receptor Genes

(2009) R. N. Pena et al.   ANIMAL BIOTECHNOLOGY

SOAP2: an improved ultrafast tool for short read alignment

(2009) R. Li et al.   BIOINFORMATICS

Tlr2 is critical for diet-induced metabolic syndrome in a murine model

(2009) Ryan W. Himes et al.   FASEB JOURNAL

Liver-specific Deficiency of Serine Palmitoyltransferase Subunit 2 Decreases Plasma Sphingomyelin and Increases Apolipoprotein E Levels

(2009) Zhiqiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A genome-wide scan for quantitative trait loci affecting serum glucose and lipids in a White Duroc × Erhualian intercross F2 population

(2009) Rongrong Chen et al.   MAMMALIAN GENOME

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis

(2009) Daniel I. Chasman et al.   PLoS Genetics

The Creb1 coactivator Crtc1 is required for energy balance and fertility

(2008) Judith Y Altarejos et al.   NATURE MEDICINE

Mapping of quantitative trait loci for cholesterol, LDL, HDL, and triglyceride serum concentrations in pigs

(2008) David Gallardo et al.   PHYSIOLOGICAL GENOMICS

Mapping the Genetic Architecture of Gene Expression in Human Liver

(2008) Eric E Schadt et al.   PLOS BIOLOGY

What Can Genome-Wide Association Studies Tell Us about the Genetics of Common Disease?

(2008) Mark M Iles   PLoS Genetics