Downregulation of Smurf2, a tumor-suppressive ubiquitin ligase, in triple-negative breast cancers: Involvement of the RB-microRNA axis

Regulation of EGFR Protein Stability by the HECT-type Ubiquitin Ligase SMURF2

(2015) Dipankar Ray et al.   NEOPLASIA

Role of microRNAs in breast cancer

(2013) Ramesh Singh et al.   CANCER BIOLOGY & THERAPY

Molecular mechanisms underlying RB protein function

(2013) Frederick A. Dick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Loss of SNAIL Regulated miR-128-2 on Chromosome 3p22.3 Targets Multiple Stem Cell Factors to Promote Transformation of Mammary Epithelial Cells

(2012) P. Qian et al.   CANCER RESEARCH

Smurf2 Regulates the Senescence Response and Suppresses Tumorigenesis in Mice

(2012) C. Ramkumar et al.   CANCER RESEARCH

MicroRNAs in breast cancer initiation and progression

(2012) Huiping Liu   CELLULAR AND MOLECULAR LIFE SCIENCES

A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20

(2012) Michael Blank et al.   NATURE MEDICINE

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state

(2012) C. Polytarchou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smurf2-mediated ubiquitination and degradation of Id1 regulates p16 expression during senescence

(2011) Yahui Kong et al.   AGING CELL

microRNA-Associated Progression Pathways and Potential Therapeutic Targets Identified by Integrated mRNA and microRNA Expression Profiling in Breast Cancer

(2011) F. M. Buffa et al.   CANCER RESEARCH

MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function

(2011) S Donzelli et al.   CELL DEATH AND DIFFERENTIATION

Reduced miR-128 in Breast Tumor-Initiating Cells Induces Chemotherapeutic Resistance via Bmi-1 and ABCC5

(2011) Y. Zhu et al.   CLINICAL CANCER RESEARCH

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-15 and miR-16 Are Direct Transcriptional Targets of E2F1 that Limit E2F-Induced Proliferation by Targeting Cyclin E

(2011) M. Ofir et al.   MOLECULAR CANCER RESEARCH

Smad Ubiquitylation Regulatory Factor 1/2 (Smurf1/2) Promotes p53 Degradation by Stabilizing the E3 Ligase MDM2

(2010) Jing Nie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcription alterations of members of the ubiquitin–proteasome network in prostate carcinoma

(2010) O J C Hellwinkel et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Most Basal-like Breast Carcinomas Demonstrate the Same Rb−/p16+ Immunophenotype as the HPV-related Poorly Differentiated Squamous Cell Carcinomas Which They Resemble Morphologically

(2009) Andrea Proctor Subhawong et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Smad Ubiquitination Regulatory Factor 2 Promotes Metastasis of Breast Cancer Cells by Enhancing Migration and Invasiveness

(2009) C. Jin et al.   CANCER RESEARCH

miR-15a and miR-16 Are Implicated in Cell Cycle Regulation in a Rb-Dependent Manner and Are Frequently Deleted or Down-regulated in Non–Small Cell Lung Cancer

(2009) Nora Bandi et al.   CANCER RESEARCH

Smurf2 Induces Ubiquitin-dependent Degradation of Smurf1 to Prevent Migration of Breast Cancer Cells

(2008) Erina Fukunaga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpoint

(2008) Evan C. Osmundson et al.   JOURNAL OF CELL BIOLOGY