Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans

Microcephaly genes and the evolution of sexual dimorphism in primate brain size

(2013) S. H. Montgomery et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Human brain evolution: transcripts, metabolites and their regulators

(2013) Mehmet Somel et al.   NATURE REVIEWS NEUROSCIENCE

p63/p73 in the control of cell cycle and cell death

(2012) N. Allocati et al.   EXPERIMENTAL CELL RESEARCH

MCPH1/BRIT1 represses transcription of the human telomerase reverse transcriptase gene

(2012) Lei Shi et al.   GENE

Identification and functional characterization of a primate-specific E2F1 binding motif regulating MCPH1 expression

(2011) Lei Shi et al.   FEBS Journal

MCPH1 regulates chromosome condensation and shaping as a composite modulator of condensin II

(2011) Daisuke Yamashita et al.   JOURNAL OF CELL BIOLOGY

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1–Cdc25 pathway

(2011) Ralph Gruber et al.   NATURE CELL BIOLOGY

Mutations in Centrosomal Protein CEP152 in Primary Microcephaly Families Linked to MCPH4

(2010) Duane L. Guernsey et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Reconstructing the ups and downs of primate brain evolution: implications for adaptive hypotheses and Homo floresiensis

(2010) Stephen H Montgomery et al.   BMC BIOLOGY

Adaptive Evolution of Four Microcephaly Genes and the Evolution of Brain Size in Anthropoid Primates

(2010) S. H. Montgomery et al.   MOLECULAR BIOLOGY AND EVOLUTION

Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations

(2010) Kaya Bilgüvar et al.   NATURE

Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture

(2010) Timothy W Yu et al.   NATURE GENETICS

WDR62 is associated with the spindle pole and is mutated in human microcephaly

(2010) Adeline K Nicholas et al.   NATURE GENETICS

E2F-1 Directly Regulates Thrombospondin 1 Expression

(2010) Wei Ji et al.   PLoS One

Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline

(2010) J. N. Pulvers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BRIT1/MCPH1 Is Essential for Mitotic and Meiotic Recombination DNA Repair and Maintaining Genomic Stability in Mice

(2010) Yulong Liang et al.   PLoS Genetics

Mutations in STIL, Encoding a Pericentriolar and Centrosomal Protein, Cause Primary Microcephaly

(2009) Arun Kumar et al.   AMERICAN JOURNAL OF HUMAN GENETICS

BRIT1/MCPH1 links chromatin remodelling to DNA damage response

(2009) Guang Peng et al.   NATURE CELL BIOLOGY

Sex-dependent association of common variants of microcephaly genes with brain structure

(2009) L. M. Rimol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Forced G1-phase reduction alters mode of division, neuron number, and laminar phenotype in the cerebral cortex

(2009) L.-J. Pilaz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Origins and Evolution of the p53 Family of Genes

(2009) V. A. Belyi et al.   Cold Spring Harbor Perspectives in Biology

MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis

(2008) Shan-Zhong Yang et al.   EMBO REPORTS

A common SNP of MCPH1 is associated with cranial volume variation in Chinese population

(2008) Jin-kai Wang et al.   HUMAN MOLECULAR GENETICS

Microcephalin/MCPH1 Associates with the Condensin II Complex to Function in Homologous Recombination Repair

(2008) Jamie L. Wood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Positive Selection in ASPM Is Correlated with Cerebral Cortex Evolution across Primates but Not with Whole-Brain Size

(2008) Farhan Ali et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genetic basis of human brain evolution

(2008) Eric J. Vallender et al.   TRENDS IN NEUROSCIENCES