MCPH1 regulates chromosome condensation and shaping as a composite modulator of condensin II

MCPH1 patient cells exhibit delayed release from DNA damage-induced G2/M checkpoint arrest 

(2011) Ioannis Gavvovidis et al.   CELL CYCLE

The relative ratio of condensin I to II determines chromosome shapes

(2011) K. Shintomi et al.   GENES & DEVELOPMENT

Differential regulation of centrosome integrity by DNA damage response proteins

(2010) Rekha Rai et al.   CELL CYCLE

Establishment of a Mouse Model with Misregulated Chromosome Condensation due to Defective Mcph1 Function

(2010) Marc Trimborn et al.   PLoS One

Releasing cohesin from chromosome arms in early mitosis: opposing actions of Wapl-Pds5 and Sgo1

(2009) K. Shintomi et al.   GENES & DEVELOPMENT

Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1

(2009) Alexandra Tibelius et al.   JOURNAL OF CELL BIOLOGY

Safeguarding Entry into Mitosis: the Antephase Checkpoint

(2009) C. F. Chin et al.   MOLECULAR AND CELLULAR BIOLOGY

The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A

(2009) Ai Takemoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Primary microcephaly: do all roads lead to Rome?

(2009) Gemma K. Thornton et al.   TRENDS IN GENETICS

MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis

(2008) Shan-Zhong Yang et al.   EMBO REPORTS

Microcephalin/MCPH1 Associates with the Condensin II Complex to Function in Homologous Recombination Repair

(2008) Jamie L. Wood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chromosome Alignment and Transvection Are Antagonized by Condensin II

(2008) T. A. Hartl et al.   SCIENCE