Small-molecule probes elucidate global enzyme activity in a proteomic context

Selective Detection of Caspase-3 versus Caspase-7 Using Activity-Based Probes with Key Unnatural Amino Acids

(2013) Chris J. Vickers et al.   ACS Chemical Biology

Two-photon probes for biomedical applications

(2013) Chang Su Lim et al.   BMB Reports

Modulation of Fatty Acid Synthase Enzyme Activity and Expression during Hepatitis C Virus Replication

(2013) Neda Nasheri et al.   CHEMISTRY & BIOLOGY

Target identification of biologically active small molecules via in situ methods

(2013) Ying Su et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Target deconvolution techniques in modern phenotypic profiling

(2013) Jiyoun Lee et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chemical reporters for biological discovery

(2013) Markus Grammel et al.   Nature Chemical Biology

Commercial prospects for genomic sequencing technologies

(2013) Sharmarke Mohamed et al.   NATURE REVIEWS DRUG DISCOVERY

Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging

(2013) H.-W. Rhee et al.   SCIENCE

Diverse Functional Roles of Reactive Cysteines

(2012) Nicholas J. Pace et al.   ACS Chemical Biology

Development of a Selective Activity-Based Probe for Adenylating Enzymes: Profiling MbtA Involved in Siderophore Biosynthesis from Mycobacterium tuberculosis

(2012) Benjamin P. Duckworth et al.   ACS Chemical Biology

Identification of a Selective, Activity-Based Probe for Glyceraldehyde 3-Phosphate Dehydrogenases

(2012) Farnusch Kaschani et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of a lead small-molecule inhibitor of anthrax lethal toxin by using fluorescence-based high-throughput screening

(2012) Dong Wei et al.   BMB Reports

Cell-Based Proteome Profiling of Potential Dasatinib Targets by Use of Affinity-Based Probes

(2012) Haibin Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional Imaging of Legumain in Cancer Using a New Quenched Activity-Based Probe

(2012) Laura E. Edgington et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activity-Based Probe for Histidine Kinase Signaling

(2012) Kaelyn E. Wilke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Chemical Proteomics Approach To Identify Post-translational Modification-Mediated Protein–Protein Interactions

(2012) Xiang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identification of Cancer Cell-Line Origins Using Fluorescence Image-Based Phenomic Screening

(2012) Jun-Seok Lee et al.   PLoS One

Quantitative Proteomic Analysis of the Effect of Fluoride on the Acquired Enamel Pellicle

(2012) Walter L. Siqueira et al.   PLoS One

Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling

(2011) Lianne I. Willems et al.   ACCOUNTS OF CHEMICAL RESEARCH

Development of Activity-Based Probes for Cathepsin X

(2011) Margot G. Paulick et al.   ACS Chemical Biology

Functional Characterization of a SUMO Deconjugating Protease of Plasmodium falciparum Using Newly Identified Small Molecule Inhibitors

(2011) Elizabeth L. Ponder et al.   CHEMISTRY & BIOLOGY

Diversity-oriented optical imaging probe development

(2011) Jun-Seok Lee et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Fluorescent labeling of membrane proteins on the surface of living cells by a self-catalytic glutathione S-transferase omega 1 tag

(2011) Jae-Jung Lee et al.   Molecular BioSystems

Site-selective labeling at Cys302 of aldehyde dehydrogenase unveils a selective mitochondrial stain

(2011) Yun Kyung Kim et al.   Molecular BioSystems

Isozyme-Specific Fluorescent Inhibitor of GlutathioneS-Transferase Omega 1

(2010) Junghyun Son et al.   ACS Chemical Biology

Diversity-oriented fluorescence library approaches for probe discovery and development

(2010) Marc Vendrell et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Super-SILAC mix for quantitative proteomics of human tumor tissue

(2010) Tamar Geiger et al.   NATURE METHODS

Decoding signalling networks by mass spectrometry-based proteomics

(2010) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Development of Near-Infrared Fluorophore (NIRF)-Labeled Activity-Based Probes forin VivoImaging of Legumain

(2009) Jiyoun Lee et al.   ACS Chemical Biology

A Suite of Activity-Based Probes for Human Cytochrome P450 Enzymes

(2009) Aaron T. Wright et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diversity-oriented fluorescence library approach for the discovery of sensors and probes

(2009) Jun-Seok Lee et al.   Molecular BioSystems

Large-scale profiling of protein palmitoylation in mammalian cells

(2009) Brent R Martin et al.   NATURE METHODS

Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry

(2008) Benjamin F. Cravatt et al.   Annual Review of Biochemistry

SILAC Mouse for Quantitative Proteomics Uncovers Kindlin-3 as an Essential Factor for Red Blood Cell Function

(2008) Marcus Krüger et al.   CELL

Activity-based probes as a tool for functional proteomic analysis of proteases

(2008) Marko Fonović et al.   Expert Review of Proteomics

Disparate proteome reactivity profiles of carbon electrophiles

(2008) Eranthie Weerapana et al.   Nature Chemical Biology