CDK6 as a key regulator of hematopoietic and leukemic stem cell activation

Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer

(2015) Dongping Li et al.   Oncotarget

Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice

(2014) A. Stoddart et al.   BLOOD

Requirement for CDK6 in MLL-rearranged acute myeloid leukemia

(2014) T. Placke et al.   BLOOD

Cdk4 and Cdk6 cooperate in counteracting the INK4 family of inhibitors during murine leukemogenesis

(2014) E. Rodriguez-Diez et al.   BLOOD

MLL fusion-driven activation ofCDK6potentiates proliferation inMLL-rearranged infant ALL

(2014) Marieke Van der Linden et al.   CELL CYCLE

AML1/Runx1 Negatively Regulates Quiescent Hematopoietic Stem Cells in Adult Hematopoiesis

(2014) M. Ichikawa et al.   JOURNAL OF IMMUNOLOGY

Cyclin-Dependent Kinase 6 Is a Chromatin-Bound Cofactor for NF-κB-Dependent Gene Expression

(2014) Katja Handschick et al.   MOLECULAR CELL

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis

(2013) Karoline Kollmann et al.   CANCER CELL

Expression of early growth response-1 in colorectal cancer and its relation to tumor cell proliferation and apoptosis

(2013) DAE-SEONG MYUNG et al.   ONCOLOGY REPORTS

Expression of early growth response-1 in human gastric cancer and its relationship with tumor cell behaviors and prognosis

(2013) Eun Myung et al.   PATHOLOGY RESEARCH AND PRACTICE

Diverging fates of cells of origin in acute and chronic leukaemia

(2012) Boris Kovacic et al.   EMBO Molecular Medicine

Kruppel-like factor 4 is involved in cell scattering induced by hepatocyte growth factor

(2012) J.-K. Lai et al.   JOURNAL OF CELL SCIENCE

CDK6 kinase activity is required for thymocyte development

(2011) M. G. Hu et al.   BLOOD

In Search of CML Stem Cells’ Deadly Weakness

(2011) Francesca Pellicano et al.   Current Hematologic Malignancy Reports

Targeting leukemic stem cells by breaking their dormancy

(2010) Marieke Alida Gertruda Essers et al.   Molecular Oncology

The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells

(2010) Olga Sirin et al.   NATURE CELL BIOLOGY

Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism

(2010) D. N. Boone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caleydo: connecting pathways and gene expression

(2009) Marc Streit et al.   BIOINFORMATICS

Scl regulates the quiescence and the long-term competence of hematopoietic stem cells

(2009) J. Lacombe et al.   BLOOD

Optimising chronic myeloid leukaemia therapy in the face of resistance to tyrosine kinase inhibitors – A synthesis of clinical and laboratory data

(2009) David A. Irvine et al.   BLOOD REVIEWS

A Requirement for Cyclin-Dependent Kinase 6 in Thymocyte Development and Tumorigenesis

(2009) M. G. Hu et al.   CANCER RESEARCH

Balancing dormant and self-renewing hematopoietic stem cells

(2009) Anne Wilson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

(2009) Chen Zhao et al.   NATURE

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

Estimating Dormant and Active Hematopoietic Stem Cell Kinetics through Extensive Modeling of Bromodeoxyuridine Label-Retaining Cell Dynamics

(2009) Richard C. van der Wath et al.   PLoS One

Ontologizer 2.0--a multifunctional tool for GO term enrichment analysis and data exploration

(2008) S. Bauer et al.   BIOINFORMATICS

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

The Transcription Factor EGR1 Controls Both the Proliferation and Localization of Hematopoietic Stem Cells

(2008) Irene M. Min et al.   Cell Stem Cell

Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells

(2008) Ivan Maillard et al.   Cell Stem Cell

GeneMANIA: a real-time multiple association network integration algorithm for predicting gene function

(2008) Sara Mostafavi et al.   GENOME BIOLOGY