Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency

Generating diversity: transcriptional regulation of effector and memory CD8+T-cell differentiation

(2015) Rachel L. Rutishauser et al.   IMMUNOLOGICAL REVIEWS

A human immunodeficiency caused by mutations in the PIK3R1 gene

(2014) Marie-Céline Deau et al.   JOURNAL OF CLINICAL INVESTIGATION

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

(2014) H. S. Kuehn et al.   SCIENCE

A comparative review of aging and B cell function in mice and humans

(2013) Jean L Scholz et al.   CURRENT OPINION IN IMMUNOLOGY

Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia

(2013) A. Rensing-Ehl et al.   HAEMATOLOGICA

Phosphoinositide 3-Kinase   Gene Mutation Predisposes to Respiratory Infection and Airway Damage

(2013) I. Angulo et al.   SCIENCE

Deleterious Mutations in LRBA Are Associated with a Syndrome of Immune Deficiency and Autoimmunity

(2012) Gabriela Lopez-Herrera et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections

(2012) Amandine Crequer et al.   JOURNAL OF CLINICAL INVESTIGATION

Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity

(2012) Guangjin Li et al.   NATURE MEDICINE

Auto-immune lymphoproliferative disorder and other secondary immune thrombocytopenias in childhood

(2012) Victoria Price   PEDIATRIC BLOOD & CANCER

Inherited MST1 Deficiency Underlies Susceptibility to EV-HPV Infections

(2012) Amandine Crequer et al.   PLoS One

Structure and function of tripeptidyl peptidase II, a giant cytosolic protease

(2011) Beate Rockel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice

(2011) Y. Hao et al.   BLOOD

Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity

(2011) A. V. Rubtsov et al.   BLOOD

AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy

(2011) M V Astle et al.   ONCOGENE

Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions

(2011) B. D. Rudd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

(2010) I. Isnardi et al.   BLOOD

MutationTaster evaluates disease-causing potential of sequence alterations

(2010) Jana Marie Schwarz et al.   NATURE METHODS

Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells

(2009) M. Rakhmanov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tripeptidyl peptidase II is dispensable for the generation of both proteasome-dependent and proteasome-independent ligands of HLA-B27 and other class I molecules

(2008) Miguel Marcilla et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

(2008) Susan Moir et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice

(2008) Jisen Huai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA