Abnormally differentiated CD4+ or CD8+ T cells with phenotypic and genetic features of double negative T cells in human Fas deficiency

Human TCR  / + CD4-CD8- Double-Negative T Cells in Patients with Autoimmune Lymphoproliferative Syndrome Express Restricted V  TCR Diversity and Are Clonally Related to CD8+ T Cells

(2014) A. Bristeau-Leprince et al.   JOURNAL OF IMMUNOLOGY

Somatic loss of heterozygosity, but not haploinsufficiency alone, leads to full-blown autoimmune lymphoproliferative syndrome in 1 of 12 family members with FAS start codon mutation

(2013) Fabian Hauck et al.   CLINICAL IMMUNOLOGY

Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia

(2013) A. Rensing-Ehl et al.   HAEMATOLOGICA

Increased T-bet is associated with senescence of influenza virus-specific CD8 T cells in aged humans

(2013) Douglas V. Dolfi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Thymic functions and gene expression profile distinct double-negative cells from single positive cells in the autoimmune lymphoproliferative syndrome

(2012) Atar Lev et al.   AUTOIMMUNITY REVIEWS

Characterization of the immunoregulatory function of human TCR-αβ+ CD4−CD8− double-negative T cells

(2011) Simon Voelkl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts

(2011) K. A. Fortner et al.   INTERNATIONAL IMMUNOLOGY

Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop

(2010) J. B. Oliveira et al.   BLOOD

Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation

(2010) Aude Magerus-Chatinet et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Lymphoproliferation Caused by Fas Deficiency Is Dependent on the Transcription Factor Eomesodermin

(2010) I. Kinjyo et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: The Transcription Factor Eomesodermin Enables CD8+ T Cells To Compete for the Memory Cell Niche

(2010) A. Banerjee et al.   JOURNAL OF IMMUNOLOGY

FAS-L, IL-10, and double-negative CD4-CD8- TCR  / + T cells are reliable markers of autoimmune lymphoproliferative syndrome (ALPS) associated with FAS loss of function

(2009) A. Magerus-Chatinet et al.   BLOOD

Comprehensive assessment of T-cell receptor  -chain diversity in    T cells

(2009) H. S. Robins et al.   BLOOD

KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells

(2009) S. M. Henson et al.   BLOOD

Phenotype and function of human T lymphocyte subsets: Consensus and issues

(2008) Victor Appay et al.   CYTOMETRY PART A

Fas-Mediated Apoptosis Regulates the Composition of Peripheral αβ T Cell Repertoire by Constitutively Purging Out Double Negative T Cells

(2008) Abdiaziz S. Mohamood et al.   PLoS One