Therapeutic activity of multiple common  -chain cytokine inhibition in acute and chronic GVHD

MiR-146a regulates the TRAF6/TNF-axis in donor T cells during GVHD

(2014) N. Stickel et al.   BLOOD

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

(2014) R. Flynn et al.   BLOOD

I B Kinase   Targets Interferon Regulatory Factor 1 in Activated T Lymphocytes

(2014) M. Sgarbanti et al.   MOLECULAR AND CELLULAR BIOLOGY

Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage

(2014) Lukas Schwab et al.   NATURE MEDICINE

Inflammatory neovascularization during graft-versus-host disease is regulated by  v integrin and miR-100

(2013) F. Leonhardt et al.   BLOOD

The Nlrp3 inflammasome regulates acute graft-versus-host disease

(2013) Dragana Jankovic et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-21 accelerates xenogeneic graft-versus-host disease correlated with increased B-cell proliferation

(2013) Xiaoran Wu et al.   Protein & Cell

The EBMT activity survey: 1990–2010

(2012) J R Passweg et al.   BONE MARROW TRANSPLANTATION

Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus

(2012) Tom M. McCaughtry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spleen tyrosine kinase (Syk) is a potent target for GvHD prevention at different cellular levels

(2012) F Leonhardt et al.   LEUKEMIA

TRIM28 prevents autoinflammatory T cell development in vivo

(2012) Shunsuke Chikuma et al.   NATURE IMMUNOLOGY

Prophylactic Effects of Interleukin-2 Receptor Antagonists against Graft-versus-Host Disease Following Unrelated Donor Peripheral Blood Stem Cell Transplantation

(2011) Jun Fang et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes

(2011) K. L. Hippen et al.   BLOOD

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL

(2011) A. M. Hanash et al.   BLOOD

Risk factors for acute GVHD and survival after hematopoietic cell transplantation

(2011) M. Jagasia et al.   BLOOD

Jak1 Has a Dominant Role over Jak3 in Signal Transduction through γc-Containing Cytokine Receptors

(2011) Claude Haan et al.   CHEMISTRY & BIOLOGY

Plasma levels of IL-7 and IL-15 in the first month after myeloablative BMT are predictive biomarkers of both acute GVHD and relapse

(2010) S Thiant et al.   BONE MARROW TRANSPLANTATION

Plasma levels of IL-7 and IL-15 after reduced intensity conditioned allo-SCT and relationship to acute GVHD

(2010) S Thiant et al.   BONE MARROW TRANSPLANTATION

Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R

(2010) Konrad Wilhelm et al.   NATURE MEDICINE

A Phase III Study of Infliximab and Corticosteroids for the Initial Treatment of Acute Graft-versus-Host Disease

(2009) Daniel R. Couriel et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation

(2009) C. Bucher et al.   BLOOD

Graft-versus-host disease

(2009) James LM Ferrara et al.   LANCET

Association of Serum Interleukin-7 Levels With the Development of Acute Graft-Versus-Host Disease

(2008) Robert M. Dean et al.   JOURNAL OF CLINICAL ONCOLOGY

Importance of Interleukin-7 in the Development of Experimental Graft-Versus-Host Disease

(2007) Brile Chung et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION