Activating STAT6 mutations in follicular lymphoma

Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells

(2014) U. Rozovski et al.   BLOOD

Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma

(2014) H. Li et al.   BLOOD

Selective JAK2 Inhibition Specifically Decreases Hodgkin Lymphoma and Mediastinal Large B-cell Lymphoma Growth In Vitro and In Vivo

(2014) Y. Hao et al.   CLINICAL CANCER RESEARCH

Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma

(2014) Jay Gunawardana et al.   NATURE GENETICS

Genetics of Follicular Lymphoma Transformation

(2014) Laura Pasqualucci et al.   Cell Reports

Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma

(2013) A. Bouska et al.   BLOOD

Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma

(2013) M. R. Green et al.   BLOOD

Cross Talk between Follicular Th Cells and Tumor Cells in Human Follicular Lymphoma Promotes Immune Evasion in the Tumor Microenvironment

(2013) S. Rawal et al.   JOURNAL OF IMMUNOLOGY

Follicular lymphoma and the immune system: from pathogenesis to antibody therapy

(2012) F. K. Stevenson et al.   BLOOD

The JAK-STAT Pathway at Twenty

(2012) George R. Stark et al.   IMMUNITY

Current and future management of follicular lymphoma

(2012) Gilles Salles et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Pathogenesis of follicular lymphoma

(2012) Robert Kridel et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathology, pathogenesis and molecular genetics of follicular NHL

(2011) E. Leich et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity

(2011) Huihui Chen et al.   CELL

Phase II Study of Vorinostat for Treatment of Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma and Mantle Cell Lymphoma

(2011) Mark Kirschbaum et al.   JOURNAL OF CLINICAL ONCOLOGY

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

(2011) Laura Pasqualucci et al.   NATURE

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

(2011) Ryan D. Morin et al.   NATURE

Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma

(2010) M. R. Green et al.   BLOOD

Acquired TNFRSF14 Mutations in Follicular Lymphoma Are Associated with Worse Prognosis

(2010) K.-J. J. Cheung et al.   CANCER RESEARCH

Implications of the tumor microenvironment on survival and disease response in follicular lymphoma

(2010) John G Gribben   CURRENT OPINION IN ONCOLOGY

Prognostic Factors in Follicular Lymphoma

(2010) Thomas Relander et al.   JOURNAL OF CLINICAL ONCOLOGY

Live Cell Imaging Reveals Continuous STAT6 Nuclear Trafficking

(2010) H.-C. Chen et al.   JOURNAL OF IMMUNOLOGY

Follicular lymphoma cell niche: identification of a preeminent IL-4-dependent TFH–B cell axis

(2010) C Pangault et al.   LEUKEMIA

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

(2010) Ryan D Morin et al.   NATURE GENETICS

Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma

(2009) O. Ritz et al.   BLOOD

Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities

(2009) A. Mottok et al.   BLOOD

STAT6 and STAT1 are essential antagonistic regulators of cell survival in classical Hodgkin lymphoma cell line

(2009) D Baus et al.   LEUKEMIA

Cytoprotective effects of IAPs revealed by a small molecule antagonist

(2008) Stefanie Galbán et al.   BIOCHEMICAL JOURNAL

Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines

(2008) D. Buglio et al.   BLOOD

IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma

(2008) K. R. Calvo et al.   BLOOD